KEGG   ENZYME: 3.1.3.44
Entry
EC 3.1.3.44                 Enzyme                                 
Name
[acetyl-CoA carboxylase]-phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
[acetyl-CoA:carbon-dioxide ligase (ADP-forming)]-phosphate phosphohydrolase
Reaction(IUBMB)
[acetyl-CoA carboxylase] phosphate + H2O = [acetyl-CoA carboxylase] + phosphate [RN:R03273]
Reaction(KEGG)
R03273
Substrate
[acetyl-CoA carboxylase] phosphate [CPD:C01247];
H2O [CPD:C00001]
Product
[acetyl-CoA carboxylase] [CPD:C01139];
phosphate [CPD:C00009]
Comment
Simultaneously dephosphorylates and activates EC 6.4.1.2 acetyl-CoA carboxylase. Acts similarly on EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase), EC 2.4.1.1 (phosphorylase), EC 2.4.1.11 [glycogen(starch) synthase], and dephosphorylates phosphoprotamine and 4-nitrophenyl phosphate. Not identical to EC 3.1.3.17 ([phosphorylase] phosphatase ) or EC 3.1.3.43 {[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase}.
History
EC 3.1.3.44 created 1983
Reference
1  [PMID:6257718]
  Authors
Krakower GR, Kim KH.
  Title
Purification and properties of acetyl-CoA carboxylase phosphatase.
  Journal
J Biol Chem 256:2408-13 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.44
IUBMB Enzyme Nomenclature: 3.1.3.44
ExPASy - ENZYME nomenclature database: 3.1.3.44
BRENDA, the Enzyme Database: 3.1.3.44
CAS: 77000-10-3

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