KEGG   ENZYME: 3.1.3.55
Entry
EC 3.1.3.55                 Enzyme                                 
Name
caldesmon-phosphatase;
SMP-I;
smooth muscle caldesmon phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
caldesmon-phosphate phosphohydrolase
Reaction(IUBMB)
caldesmon phosphate + H2O = caldesmon + phosphate [RN:R02885]
Reaction(KEGG)
R02885
Substrate
caldesmon phosphate [CPD:C01022];
H2O [CPD:C00001]
Product
caldesmon [CPD:C00759];
phosphate [CPD:C00009]
Comment
Dephosphorylation activates the calmodulin- and actin-binding ability of the protein caldesmon.
History
EC 3.1.3.55 created 1989
Reference
1  [PMID:6150036]
  Authors
Ngai PK, Walsh MP.
  Title
Inhibition of smooth muscle actin-activated myosin Mg2+-ATPase activity by caldesmon.
  Journal
J Biol Chem 259:13656-9 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.55
IUBMB Enzyme Nomenclature: 3.1.3.55
ExPASy - ENZYME nomenclature database: 3.1.3.55
BRENDA, the Enzyme Database: 3.1.3.55
CAS: 93229-71-1

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