KEGG ENZYME: 3.1.7.11

ENZYME: 3.1.7.11

Entry

EC 3.1.7.11                 Enzyme

Name

geranyl diphosphate diphosphatase;
geraniol synthase;
geranyl pyrophosphate pyrophosphatase;
GES;
CtGES

Class

Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases

Sysname

geranyl-diphosphate diphosphohydrolase

Reaction(IUBMB)

geranyl diphosphate + H2O = geraniol + diphosphate [RN:R08396]

Reaction(KEGG)

R08396

Substrate

geranyl diphosphate [CPD:C00341];
H2O [CPD:C00001]

Product

geraniol [CPD:C01500];
diphosphate [CPD:C00013]

Comment

Isolated from Ocimum basilicum (basil) and Cinnamomum tenuipile (camphor tree). Requires Mg2+ or Mn2+. Geraniol is labelled when formed in the presence of [18O]H2O. Thus mechanism involves a geranyl cation [1]. Neryl diphosphate is hydrolysed more slowly. May be the same as EC 3.1.7.3 monoterpenyl-diphosphatase.

History

EC 3.1.7.11 created 2012

Pathway

ec00902

Monoterpenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K20979

geranyl diphosphate diphosphatase