Entry
Name
membrane Pro-Xaa carboxypeptidase;
carboxypeptidase P;
microsomal carboxypeptidase;
membrane Pro-X carboxypeptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metallocarboxypeptidases
BRITE hierarchy
Reaction(IUBMB)
Release of a C-terminal residue other than proline, by preferential cleavage of a prolyl bond
Comment
One of the renal brush border exopeptidases
History
EC 3.4.17.16 created 1992
Reference
Authors
Dehm P, Nordwig A.
Title
The cleavage of prolyl peptides by kidney peptidases. Isolation of a microsomal carboxypeptidase from swine kidney.
Journal
Reference
Authors
Booth AG, Hubbard LM, Kenny AJ.
Title
Proteins of the kidney microvillar membrane. Immunoelectrophoretic analysis of the membrane hydrolases: identification and resolution of the detergent- and proteinase-solubilized forms.
Journal
Reference
Authors
Hedeager-Sorensen S, Kenny AJ.
Title
Proteins of the kidney microvillar membrane. Purification and properties of carboxypeptidase P from pig kidneys.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 3.4.17.16