KEGG   ENZYME: 3.4.21.55
Entry
EC 3.4.21.55                Enzyme                                 
Name
venombin AB;
gabonase;
okinaxobin II;
Bitis gabonica venom serine proteinase;
afaacytin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
Reaction(IUBMB)
Selective cleavage at Arg! bonds in fibrinogen to form fibrin and release fibrinopeptides A and B
Comment
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin
History
EC 3.4.21.55 created 1989
Reference
1  [PMID:3522580]
  Authors
Pirkle H, Theodor I, Miyada D, Simmons G.
  Title
Thrombin-like enzyme from the venom of Bitis gabonica. Purification, properties, and coagulant actions.
  Journal
J Biol Chem 261:8830-5 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.55
IUBMB Enzyme Nomenclature: 3.4.21.55
ExPASy - ENZYME nomenclature database: 3.4.21.55
BRENDA, the Enzyme Database: 3.4.21.55
CAS: 104003-74-9

  All links  
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
All databases (2)   

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