Entry
Name
streptogrisin A;
Streptomyces griseus protease A;
protease A;
proteinase A;
Streptomyces griseus proteinase A;
Streptomyces griseus serine proteinase 3;
Streptomyces griseus serine proteinase A
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins with specificity similar to chymotrypsin
Comment
From Streptomyces griseus. A component of Pronase, in family S1 (trypsin family). Not inhibited by Tos-Phe-CH2Cl or ovomucoid
History
EC 3.4.21.80 created 1993
Orthology
Genes
SANL : KZO11_34610 KZO11_35135
SCYE : R2B67_01050 R2B67_03525
SLIA : HA039_00285 HA039_06560
» show all
Taxonomy
Reference
Authors
Johnson P, Smillie LB.
Title
The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus.
Journal
Reference
Authors
Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN.
Title
Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution.
Journal
Sequence
Reference
Authors
James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA.
Title
Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis.
Journal
Reference
Authors
Delbaere LT, Brayer GD.
Title
The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates.
Journal
Reference
Authors
Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT
Title
Characterization and structure of genes for proteases A and B from Streptomyces griseus.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 3.4.21.80