Entry |
|
Name |
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
|
Reaction(IUBMB) |
Specific cleavage of Arg!Ile bond in Factor X to form Factor Xa
|
Comment |
Apparently produced only by malignant and fetal cells
|
History |
EC 3.4.22.26 created 1992
|
Reference |
|
Authors |
Falanga A, Gordon SG. |
Title |
Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue. |
Journal |
|
Reference |
|
Authors |
Falanga A, Shaw E, Donati MB, Consonni R, Barbui T, Gordon S. |
Title |
Inhibition of cancer procoagulant by peptidyl diazomethyl ketones and peptidyl sulfonium salts. |
Journal |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 3.4.22.26 |
|