KEGG   ENZYME: 3.4.22.6
Entry
EC 3.4.22.6                 Enzyme                                 
Name
chymopapain;
chymopapain A;
chymopapain B;
chymopapain S
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
Reaction(IUBMB)
Similar to that of papain
Comment
The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family).
History
EC 3.4.22.6 created 1961 as EC 3.4.4.11, transferred 1972 to EC 3.4.22.6
Orthology
K20738  chymopapain
Genes
CPAP110826048
Reference
1
  Authors
Brocklehurst, K., Willenbrock, F. and Salih, E.
  Title
Cysteine proteinases.
  Journal
In: Neuberger, A. and Brocklehurst, K. (Eds.), New Comprehensive Biochemistry: Hydrolytic Enzymes, Elsevier, Amsterdam, 1987, p. 39-158.
Reference
2  [PMID:2500950]
  Authors
Jacquet A, Kleinschmidt T, Schnek AG, Looze Y, Braunitzer G
  Title
The thiol proteinases from the latex of Carica papaya L. III. The primary structure of chymopapain.
  Journal
Biol Chem Hoppe Seyler 370:425-34 (1989)
DOI:10.1515/bchm3.1989.370.1.425
  Sequence
Reference
3  [PMID:2085414]
  Authors
Buttle DJ, Dando PM, Coe PF, Sharp SL, Shepherd ST, Barrett AJ.
  Title
The preparation of fully active chymopapain free of contaminating proteinases.
  Journal
Biol Chem Hoppe Seyler 371:1083-8 (1990)
DOI:10.1515/bchm3.1990.371.2.1083
Other DBs
ExplorEnz - The Enzyme Database: 3.4.22.6
IUBMB Enzyme Nomenclature: 3.4.22.6
ExPASy - ENZYME nomenclature database: 3.4.22.6
BRENDA, the Enzyme Database: 3.4.22.6
CAS: 9001-09-6

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