Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of insulin B chain with specificity similar to that of thermolysin, preferring hydrophobic P1' residue. Activates the glutamyl endopeptidase (EC 3.4.21.19) of Staphylococcus aureus
Comment
A metalloenzyme from S. aureus earlier confused with staphylokinase (a non-enzymic activator of plasminogen).
History
EC 3.4.24.29 created 1972 as EC 3.4.24.4, part transferred 1992 to EC 3.4.24.29