| Entry |
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| Name |
saccharolysin;
proteinase yscD (gene name) (gene name);
yeast cysteine proteinase D (Misleading);
Saccharomyces cerevisiae proteinase yscD (gene name)
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
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| Reaction(IUBMB) |
Cleavage of Pro!Phe and Ala!Ala bonds
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| Comment |
An 83 kDa cytoplasmic thiol-dependent metalloendopeptidase from Saccharomyces cerevisiae. In peptidase family M3 (thimet oligopeptidase family).
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| History |
EC 3.4.24.37 created 1989 as EC 3.4.22.22, transferred 1992 to EC 3.4.24.37
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| Orthology |
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| Genes |
| NCS: | NCAS_0B09070(NCAS0B09070) |
| NDI: | NDAI_0A00180(NDAI0A00180) |
| TPF: | TPHA_0E03970(TPHA0E03970) |
| TBL: | TBLA_0A07560(TBLA0A07560) |
| KAF: | KAFR_0D00180(KAFR0D00180) |
| KNG: | KNAG_0C00260(KNAG0C00260) |
| PIC: | PICST_28404(PRD1.2) PICST_51091(PRD1.1) |
| CAL: | CAALFM_C105300CA(PRD1) |
| YLI: | YALI0F07667g YALI0F20988g |
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| Reference |
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| Authors |
Achstetter T, Ehmann C, Wolf DH. |
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| Title |
Proteinase yscD. Purification and characterization of a new yeast peptidase. |
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| Journal |
J Biol Chem 260:4585-90 (1985) |
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| Reference |
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| Authors |
Garcia-Alvarez N, Teichert U, Wolf DH. |
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| Title |
Proteinase yscD mutants of yeast. Isolation and characterization. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.24.37 |
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