KEGG   ENZYME: 3.4.24.43
Entry
EC 3.4.24.43                Enzyme                                 
Name
atroxase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of His5!Leu, Ser9!His, His10!Leu, Ala14!Leu and Tyr16!Leu of insulin B chain
Comment
A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that cleaves fibrinogen. In peptidase family M12 (astacin family)
History
EC 3.4.24.43 created 1992
Orthology
K20747  atroxase
Reference
1  [PMID:3167016]
  Authors
Willis TW, Tu AT
  Title
Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom.
  Journal
Biochemistry 27:4769-77 (1988)
DOI:10.1021/bi00413a028
  Sequence
[ag:AAB33788]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.43
IUBMB Enzyme Nomenclature: 3.4.24.43
ExPASy - ENZYME nomenclature database: 3.4.24.43
BRENDA, the Enzyme Database: 3.4.24.43
CAS: 181186-94-7

  All links  
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   InterPro (3)   
All databases (7)   

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