ruberlysin;
Crotalus ruber metalloendopeptidase II;
hemorrhagic toxin II
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of His10!Leu, Ala14!Leu, Tyr16!Leu and Gly23!Phe bonds in the B chain of insulin; His!Pro, Pro!Phe, and Trp!Ser of angiotensin I; and Gly!Phe of Met enkephalin
Comment
A 25 kDa hemorrhagic endopeptidase from the venom of the red rattlesnake (Crotalus ruber ruber) that cleaves fibrinogen. In peptidase family M12 (astacin family)