KEGG ENZYME: 3.4.24.51

ENZYME: 3.4.24.51

Entry

EC 3.4.24.51                Enzyme

Name

ophiolysin;
Ophiophagus metalloendopeptidase

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases

Reaction(IUBMB)

Cleavage of Asn3!Gln, Gln4!His, His10!Leu, Ala14!Leu, and Tyr16!Leu in insulin B chain

Comment

A 70 kDa endopeptidase from the venom of the king cobra (Ophiophagus hannah)

History

EC 3.4.24.51 created 1992

Reference

1 [PMID:3070833]

Authors

Yamakawa Y, Omori-Satoh T.

Title

A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain.

Journal

Toxicon 26:1145-55 (1988)
DOI:10.1016/0041-0101(88)90299-1

Other DBs

ExplorEnz - The Enzyme Database:

IUBMB Enzyme Nomenclature:

ExPASy - ENZYME nomenclature database:

BRENDA, the Enzyme Database:

All links

No link information was found.

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