KEGG   ENZYME: 3.4.24.54
Entry
EC 3.4.24.54                Enzyme                                 
Name
mucrolysin;
Trimeresurus metalloendopeptidase A;
mucrotoxin A
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of Ser9!His, His10!Leu, Ala14!Leu, Leu15!Tyr and Tyr16!Leu bonds in insulin B chain
Comment
A 94 kDa hemorrhagic and fibrinogenolytic endopeptidase from the Chinese habu snake (Trimeresurus mucrosquamatus) venom. In peptidase family M12 (astacin family)
History
EC 3.4.24.54 created 1992
Reference
1  [PMID:6857709]
  Authors
Sugihara H, Moriura M, Nikai T.
  Title
Purification and properties of a lethal, hemorrhagic protein, "Mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus).
  Journal
Toxicon 21:247-55 (1983)
DOI:10.1016/0041-0101(83)90009-0
Reference
2  [PMID:3904081]
  Authors
Kishida M, Nikai T, Mori N, Kohmura S, Sugihara H
  Title
Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake).
  Journal
Toxicon 23:637-45 (1985)
DOI:10.1016/0041-0101(85)90368-x
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.54
IUBMB Enzyme Nomenclature: 3.4.24.54
ExPASy - ENZYME nomenclature database: 3.4.24.54
BRENDA, the Enzyme Database: 3.4.24.54
CAS: 85898-38-0

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