KEGG ENZYME: 3.4.24.55

ENZYME: 3.4.24.55

Entry

EC 3.4.24.55                Enzyme

Name

pitrilysin;
Escherichia coli protease III;
protease Pi;
proteinase Pi;
PTR;
Escherichia coli metalloproteinase Pi

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases

Reaction(IUBMB)

Preferential cleavage of -Tyr16! Leu- and -Phe25! Tyr-bonds of oxidized insulin B chain. Also acts on other substrates of less than 7 kDa such as insulin and glucagon

Comment

From the periplasmic space of Escherichia coli. Inhibited by EDTA and 1,10-phenanthroline; not thiol-dependent. Type example of peptidase family M16

History

EC 3.4.24.55 created 1992 as EC 3.4.99.44, transferred 1993 to EC 3.4.24.55 (EC 3.4.99.45 created 1992, incorporated 1993)

Orthology

K01407

protease III

Genes

ECO:	b2821(ptrA)

ECJ:	JW2789(ptr)

ECD:	ECDH10B_2991(ptrA)

EBW:	BWG_2556(ptrA)

ECOK:

ECMDS42_2327(ptr)

ECOC:

C3026_15490

ECE:	Z4138(ptr)

ECS:	ECs_3678(ptrA)

ECF:	ECH74115_4086(ptrA)

ETW:	ECSP_3773(ptr)

ELX:	CDCO157_3433

EOI:	ECO111_3549(ptr)

EOJ:	ECO26_3893(ptr)

EOH:	ECO103_3380(ptr)

ECOO:

ECRM13514_3684(ptr)

ECOH:

ECRM13516_3548(ptr)

ESL:

O3K_05405

ESO:

O3O_20245

ESM:

O3M_05450

ECK:	EC55989_3097(ptr)

ECG:	E2348C_3090(ptr)

EOK:	G2583_3475(ptrA)

ELR:	ECO55CA74_16555

ELH:

ETEC_3008

ECW:	EcE24377A_3141(ptrA)

EUN:	UMNK88_3505

ECP:

ECP_2833

ENA:	ECNA114_2879(ptr)

ECOS:

EC958_5045(ptrA)

ECV:	APECO1_3684(ptrA)

ECOA:

APECO78_17710

ECX:	EcHS_A2967(ptrA)

ECM:	EcSMS35_2968(ptrA)

ECY:

ECSE_3078

ECR:	ECIAI1_2929(ptr)

ECQ:	ECED1_3277(ptr)

EUM:	ECUMN_3148(ptr)

ECT:	ECIAI39_3240(ptr)

EOC:	CE10_3248(ptrA)

EBR:	ECB_02669(ptr)

ECOB:

C3029_18075

EBL:	ECD_02669(ptrA)

EBE:	B21_02630(ptrA)

EBD:

ECBD_0904

ECI:	UTI89_C3222(ptrA)

EIH:	ECOK1_3225(ptrA)

ECZ:	ECS88_3116(ptr)

ECC:	c3415(ptr)

ELO:	EC042_3017(ptrA)

ELN:	NRG857_13935

ESE:

ECSF_2636

ECL:	EcolC_0894

EKO:	EKO11_0920

EKF:	KO11_08700(ptrA)

EAB:	ECABU_c31170(ptr)

EDH:	EcDH1_0870

EDJ:	ECDH1ME8569_2728(ptrA)

ELU:	UM146_02320

ELW:	ECW_m3063(ptrA)

ELL:	WFL_14960(ptrA)

ELC:	i14_3137(ptr)

ELD:	i02_3137(ptr)

ELP:	P12B_c2915(ptrA)

ELF:	LF82_1765(ptrA)

ECOL:

LY180_14485

ECOI:

ECOPMV1_03108(ptrA)

ECOJ:

P423_15605

EFE:	EFER_2754(ptr)

EAL:	EAKF1_ch3195(ptrA)

EMA:	C1192_21470

ESZ:	FEM44_04025

ERUY:

OSH18_17645(ptrA)

STY:	STY3133(ptr)

STT:	t2903(ptr)

SEX:	STBHUCCB_30600

SENT:

TY21A_14675

STM:	STM2995(ptr)

SEO:	STM14_3610(ptr)

SEV:	STMMW_29561

SEY:	SL1344_2973(ptr)

SEM:	STMDT12_C30450

SEJ:	STMUK_2983(ptr)

SEB:	STM474_3141(ptr)

SEF:	UMN798_3254(ptr)

SETU:

STU288_15140

SETC:

CFSAN001921_02095

SENR:

STMDT2_28941(ptr)

SEND:

DT104_29911(ptr)

SENI:

CY43_15620

SEEN:

SE451236_21070

SPT:	SPA2860(ptr)

SEK:

SSPA2663

SPQ:	SPAB_03726

SEI:	SPC_3052(ptr)

SEC:	SCH_2933(ptr)

SEH:	SeHA_C3207

SHB:

SU5_03483

SENH:

CFSAN002069_17245

SEEH:

SEEH1578_01025

SEE:	SNSL254_A3221

SENN:

SN31241_41050

SEW:	SeSA_A3158

SEA:	SeAg_B3141

SENS:

Q786_14480

SED:

SeD_A3321

SEG:	SG2903(ptr)

SEL:	SPUL_3003(ptr)

SEGA:

SPUCDC_2989(ptr)

SET:	SEN2837(ptr)

SENA:

AU38_14415

SENO:

AU37_14425

SENV:

AU39_14420

SENQ:

AU40_16230

SENL:

IY59_15020

SENJ:

CFSAN001992_18600

SEEC:

CFSAN002050_21330

SEEB:

SEEB0189_005150

SENB:

BN855_30550

SENE:

IA1_14415

SENC:

SEET0819_21840

SES:	SARI_04665

SBG:	SBG_2601(ptr)

SBZ:

A464_3011

SBV:	N643_12735

SALZ:

EOS98_04455

SFL:	SF2832(ptr)

SFX:	S3029(ptr)

SFV:	SFV_2899(ptr)

SFE:	SFxv_3105(ptrA)

SFN:

SFy_4036

SFS:

SFyv_4114

SFT:	NCTC1_03117(ptrA)

SSN:	SSON_2978(ptr)

SBO:	SBO_2711(ptr)

SBC:	SbBS512_E3041(ptrA)

SDY:	SDY_3038(ptr)

SDZ:	Asd1617_04070

SHQ:	A0259_17710

ENC:

ECL_04144

ENL:	A3UG_18250

ECLG:

EC036_35650

ECLE:

ECNIH2_18425

ECLN:

ECNIH4_04710

ECLI:

ECNIH5_17205

ECLX:

LI66_18110

ECLY:

LI62_19570

ECLZ:

LI64_17015

ECLO:

ENC_30570

EHM:	AB284_07680

EXF:	BFV63_17740

ECLA:

ECNIH3_17290

ECLC:

ECR091_17225

EAU:	DI57_01230

EKB:	BFV64_18750

ENO:	ECENHK_17955

EEC:	EcWSU1_03620(ptrA)

ELG:	BH714_21665

ECAN:

CWI88_04405

ERN:	BFV67_17750

ECLS:

LI67_019275

ECHG:

FY206_19785

ESH:	C1N69_18480

EPT:	HWQ17_17975(ptrA)

ENT:	Ent638_3264

EAS:	Entas_3510

ENR:	H650_10315

ENX:	NI40_017875

ENF:	AKI40_0943

LNI:	CWR52_16985

EBG:	FAI37_11110

END:	A4308_02700

ENZ:	G0034_18420(ptrA)

ENS:	HWQ15_03480(ptrA)

ENK:	LOC22_06255(ptrA)

EHU:	D5067_0004615

EMOR:

L6Y89_17435(ptrA)

ENB:	ELK40_18540

EQU:	OM418_17735(ptrA)

EPU:	QVH39_18770(ptrA)

ESA:

ESA_00488

CSK:	ES15_0754(ptr)

CSZ:	CSSP291_02520

CSJ:	CSK29544_01745

CCON:

AFK62_15900

CDM:	AFK67_16660

CSI:	P262_01119

CMJ:	AFK66_003610

CUI:	AFK65_15670

CMW:	AFK63_02590

CTU:	CTU_33700(ptrA)

KPN:	KPN_03230(ptr)

KPU:	KP1_4499(ptr)

KPM:	KPHS_42930

KPP:

A79E_0880

KPH:	KPNIH24_07325

KPZ:	KPNIH27_20805

KPV:	KPNIH29_21575

KPW:	KPNIH30_21595

KPY:	KPNIH31_20860

KPG:	KPNIH32_22455

KPC:	KPNIH10_21390

KPQ:	KPR0928_20880

KPT:	VK055_4295

KPO:	KPN2242_19100

KPR:	KPR_1803(ptrA)

KPJ:

N559_1008

KPI:	D364_16395

KPA:	KPNJ1_01014

KPS:	KPNJ2_01045

KPX:	PMK1_00711(ptrA_1)

KPB:	FH42_12110

KPNE:

KU54_004975

KPNU:

LI86_04985

KPNK:

BN49_0878(ptrA)

KVA:

Kvar_0840

KPE:	KPK_0885(ptrA)

KVD:	KR75_03730

KVQ:	SP68_10275

KOX:

KOX_01575

KOE:

A225_4780

KOY:	J415_08120

KOM:	HR38_00030

KMI:	VW41_19315

KOK:	KONIH1_24015

KOC:	AB185_12375

KQU:	AVR78_25900

EAE:

EAE_02105

EAR:

CCG33570

KQV:	B8P98_04900

KLL:	BJF97_23845

KLW:	DA718_05340

KAR:	LGL98_04480(ptrA)

KGR:	JJJ10_05365(ptrA)

KPAS:

LUW96_01675(ptrA)

KLC:	K7H21_05020(ptrA)

KLM:	BWI76_23235

REE:	electrica_00886(ptrA)

ROR:	RORB6_23415

RON:	TE10_22845

RPLN:

B1209_04765

RAO:	DSD31_04885

RTG:	NCTC13098_01296(ptrA)

CRO:	ROD_28631(ptrA)

CKO:

CKO_04186

CFD:	CFNIH1_01065

CBRA:

A6J81_21945

CWE:	CO701_03230

CYO:	CD187_04750

CPOT:

FOB25_16080

CFQ:	C2U38_20335

CSED:

JY391_04385(ptrA)

CAMA:

F384_15290

CAF:	AL524_07680

CIF:	AL515_18710

CFAR:

CI104_20320

CIR:	C2U53_14660

CIE:	AN232_09295

CPAR:

CUC49_14555

CTEL:

GBC03_09500

CITZ:

E4Z61_21365

CARS:

E1B03_21425

CIX:	M4I31_04570(ptrA)

CIB:	HF677_004475(ptrA)

CENS:

P2W74_04420(ptrA)

EBT:	EBL_c08090(ptr)

CNT:	JT31_16390

CEM:	LH23_01320

CEN:	LH86_01305

CLAP:

NCTC11466_00689(ptrA)

PGE:	LG71_09205

ESC:	Entcl_0909

KLE:	AO703_17045

KSA:	C813_20035

KOR:	AWR26_04650(ptrA)

KRD:	A3780_19405

KCO:	BWI95_05640

KOT:	EH164_04065

KPSE:

IP581_18580(ptrA)

KOB:	HF650_19450(ptrA)

KOO:	O9K67_04655(ptrA)

KIE:	NCTC12125_04851(ptrA_1)

KAS:	KATP_08740

KLU:	K7B04_09690(ptrA)

KCY:	RIN60_04450(ptrA)

LAX:	APT61_04460

LEI:	C2U54_23630

LEH:	C3F35_16250

LEE:	DVA44_04575

LER:	GNG29_18495

LEA:	GNG26_17900

LPNU:

KQ929_03780(ptrA)

LEY:	DVA43_23040

LAZ:	A8A57_16935

LEF:	LJPFL01_3327

LEW:	DAI21_09210

BAGE:

BADSM9389_08680

BFT:	MNO13_04350(ptrA)

SYM:	K6K13_19295(ptrA)

AHN:	NCTC12129_04010(ptrA)

ASUB:

NLZ15_04065(ptrA)

YRE:	HEC60_13695(ptrA)

SGOE:

A8O29_004825(ptrA)

KIN:	AB182_04345

PDZ:	HHA33_07210(ptrA)

METY:

MRY16398_09980(ptrA)

IZH:	FEM41_00445

PTF:	PROFFT_A_02210(ptrA)

PLAR:

GII40_00217(ptrA)

PSHI:

SAMEA2665130_2427(ptrA_2)

PSGC:

G163CM_45260(ptrA)

SCOL:

KFZ77_15770(ptrA)

PVJ:	LMA04_16305(ptrA)

SUPE:

P0H77_17395(ptrA)

TOE:	QMG90_05300(ptrA)

EBF:

D782_0900

EBC:	C2U52_14150

EBU:	CUC76_20160

EBB:

F652_2504

PSTS:

E05_46520

YPE:	YPO1019(ptr)

YPK:	y3165(ptr)

YPH:	YPC_1050(ptr)

YPA:

YPA_0491

YPN:

YPN_2982

YPM:	YP_2882(ptrA)

YPP:	YPDSF_1696

YPG:	YpAngola_A3232(ptrA)

YPZ:	YPZ3_0927(ptrA)

YPT:	A1122_20925

YPD:	YPD4_0884(ptrA)

YPX:	YPD8_1187(ptrA)

YPJ:

CH55_3766

YPV:

BZ15_2553

YPL:

CH46_4127

YPS:	YPTB3026(ptrA)

YPO:

BZ17_3591

YPI:	YpsIP31758_0990(ptrA)

YPY:

YPK_1042

YPB:

YPTS_3148

YPQ:

DJ40_3451

YPU:

BZ21_2344

YPR:

BZ20_3135

YPC:

BZ23_2623

YPF:

BZ19_2407

YEN:	YE3311(ptrA)

YEP:	YE105_C0946

YEY:

Y11_40751

YEL:	LC20_01108

YEW:

CH47_231

YET:

CH48_765

YEF:	FORC2_0841

YEE:	YE5303_05851(ptrA)

YSI:	BF17_01630

YAL:

AT01_1628

YFR:	AW19_2293(ptrA)

YIN:

CH53_2693

YKR:

CH54_3493

YRO:

CH64_1700

YRU:

BD65_1221

YRB:	UGYR_06840

YAK:	ACZ76_04790

YMA:	DA391_04700

YHI:	D5F51_17345

YCA:	F0T03_17180

YMO:	HRD69_00545(ptrA)

YAS:	N0H69_07715(ptrA)

YKI:	HRD70_00140(ptrA)

YEG:	PL78_08790

SMAR:

SM39_3418(ptrA)

SMAC:

SMDB11_3208(ptrA)

SMW:	SMWW4_v1c39360(ptrA)

SPE:

Spro_3815

SRR:	SerAS9_4004

SRL:	SOD_c37810(ptrA)

SRY:	M621_20315

SPLY:

Q5A_020140(ptrA_2)

SRS:	SerAS12_4005

SRA:	SerAS13_4005

SMAF:

D781_3558

SLQ:	M495_19915

SERF:

L085_09010

SERS:

SERRSCBI_19060

SFW:	WN53_01910

SFG:	AV650_24680

SRZ:	AXX16_1520

SERM:

CLM71_18670

SQU:	E4343_21340

SFJ:	SAMEA4384070_3936(ptrA_2)

SOF:	NCTC11214_02814(ptrA_1)

SSUR:

ATE40_016385

SURI:

J0X03_04300(ptrA)

SRHZ:

FO014_15545

SENP:

KHA73_19165(ptrA)

SNEM:

NLX84_19830(ptrA)

SNEV:

OI978_12300(ptrA)

SFO:	Z042_06145

RAH:	Rahaq_0840

RACE:

JHW33_20865(ptrA)

RAQ:	Rahaq2_0897

RAA:

Q7S_03950

ROX:	BV494_21135

RVC:	J9880_11815(ptrA)

RBON:

QNM34_04280(ptrA)

RIU:	I2123_06165(ptrA)

GQU:	AWC35_16625

EAME:

GXP68_03440(ptrA)

RBAD:

H2866_04040(ptrA)

CARU:

P0E69_04135(ptrA)

NIG:	C1N62_03180

PROD:

PCO85_05865(ptrA)

SERA:

Ser39006_019630

SERQ:

CWC46_19630

ECA:	ECA0994(ptrA)

PATR:

EV46_05075

PATO:

GZ59_10290

PCT:

PC1_0913

PCC:	PCC21_009370

PCV:	BCS7_04825

PWA:	Pecwa_3390

PPAR:

A8F97_01700

PEC:

W5S_3392

PWS:	A7983_13720

PPOA:

BJK05_21605

PBRA:

B5S52_16970

PPUJ:

E2566_05230

PARI:

I2D83_17405(ptrA)

PAQU:

DMB82_0015880(ptrA)

PVZ:	OA04_10460(ptrA)

PPAV:

LOZ86_17070(ptrA)

PQU:	IG609_015530(ptrA)

PPOO:

LW347_05190(ptrA)

PCAC:

OI450_03980(ptrA)

PACB:

M9782_07135(ptrA)

DDD:	Dda3937_00856(ptr)

DZE:	Dd1591_3190

DDC:	Dd586_0905

DZC:	W909_04775

DSO:	A4U42_13835

CED:	LH89_07420

DFN:	CVE23_05240

DDQ:

DDI_0751

DAQ:	DAQ1742_03353(ptr)

DIC:	Dpoa569_002823

DLC:	O1Q98_16630(ptrA)

DDA:	Dd703_3008

BGJ:	AWC36_13585

BRB:	EH207_03605

BNG:	EH206_17695

BIZ:	HC231_18050(ptrA)

SGL:

SG1974

SOD:	Sant_0861(ptrA)

PES:	SOPEG_3434(ptrA)

SLIG:

GTU79_04955(ptrA)

EAM:	EAMY_0710(ptrA)

EAY:	EAM_2730(ptrA)

ETA:	ETA_27470(ptrA)

EPY:	EpC_28660(ptrA)

EPR:	EPYR_03101(ptrA)

EBI:	EbC_35780(ptrA)

ERJ:	EJP617_18700(ptrA)

EPE:	CI789_00410

ERWI:

GN242_04060

ETP:	LU633_18560(ptrA)

ERP:	LJN55_18365(ptrA)

ETO:	RIN69_18025(ptrA)

EGE:	EM595_2851(ptr)

PAM:	PANA_3108(ptrA)

PLF:	PANA5342_0924(ptrA)

PAJ:	PAJ_2383(ptrA)

PAQ:	PAGR_g0927

PVA:	Pvag_2494(ptr)

PAGG:

AL522_19630

PAO:	Pat9b_3125

KLN:	LH22_06760

PANT:

PSNIH1_02235

PANP:

PSNIH2_02185

PAGC:

BEE12_03030

PSTW:

DSJ_04965

PALH:

B1H58_11340

PANS:

FCN45_15165

PEY:	EE896_04045

PDIS:

D8B20_13795

PER:	LAC65_12780(ptrA)

PJI:	KTJ90_03935(ptrA)

PANO:

OJ965_06390(ptrA)

KPIE:

N5580_14375(ptrA)

PALF:

K6R05_03980(ptrA)

PGZ:	C2E15_17000

PCD:	C2E16_16885

MINT:

C7M51_02576(ptrA_1)

MTHI:

C7M52_00280(ptrA_1)

MHAN:

K6958_16545(ptrA)

PLU:	plu0631(ptrA)

PLUM:

A4R40_03115

PAY:	PAU_00590(ptrA)

PTT:	VY86_04745

PAKH:

B0X70_03655

PLUI:

CE143_03590

PMR:	PMI2310(ptrA)

PMIB:

BB2000_2451(ptrA)

PVL:	AOB99_13510

PVG:	CRN77_07435

PHAU:

PH4a_03815

PROT:

BTA34_13410

PCOL:

F1325_15010

PCIB:

F9282_15455

PPEE:

I6G31_12780(ptrA)

XBO:	XBJ1_3698(ptrA)

XBV:	XBW1_4208(ptrA)

XNE:	XNC1_4037(ptrA)

XNM:	XNC2_3891(ptrA)

XDO:	XDD1_3362(ptrA)

XPO:	XPG1_0267(ptrA)

XHO:	A9255_18080

XBU:	HGO23_16875(ptrA)

XGR:	QL128_18025(ptrA)

PSI:

S70_14890

PSX:

DR96_320

PSTA:

BGK56_17330

PTHA:

OI982_08700(ptrA)

PRG:	RB151_035780(ptrA_2)

PALA:

CO695_08220

PHEI:

NCTC12003_03087(ptrA)

PRQ:	CYG50_20615

PRJ:	NCTC6933_03187(ptrA)

PVC:	G3341_15740(ptrA)

PMAG:

JI723_15905(ptrA)

PHAG:

PZ638_16065(ptrA)

MMK:

MU9_909

ANS:	ArsFIN_05880(ptrA)

AET:	LDL57_03800(ptrA)

AAPC:

QG404_03630(ptrA)

MWI:	MNY66_02600(ptrA)

EIC:	NT01EI_0807

ETR:	ETAE_0709(ptrA)

ETD:

ETAF_0651

ETE:

ETEE_2474

ETC:	ETAC_03425

EDW:	QY76_16770

EDL:	AAZ33_03355(ptrA)

EHO:	A9798_12995

HAV:	AT03_17605

HPAR:

AL518_08810

OPO:	DSM2777_07640

LPV:	HYN51_13420

PRAG:

EKN56_03870

PFQ:	QQ39_14225

LRI:	NCTC12151_00676(ptrA)

HDU:	HD_0187(ptrA)

HPAA:

E5Q53_06580

HAP:	HAPS_1009(ptrA)

HPAS:

JL26_01885

HPAK:

JT17_10770

GLE:	CJD39_08390

PSKY:

A6B44_01260

PATL:

KGI96_06800(ptrA)

MHT:

D648_3150

MHQ:	D650_24990

MHAT:

B824_23560

MHX:	MHH_c08610(ptrA)

MHAE:

F382_09450

MHAM:

J450_08380

MHAO:

J451_09670

MHAL:

N220_01540

MHAQ:

WC39_12310

MHAY:

VK67_12315

MVR:	X781_21600

MVI:

X808_2070

MVG:

X874_2160

MVE:	X875_18760

MGRA:

A4G16_08715

MBOS:

ICJ55_03225(ptrA)

MPEG:

HV560_01330(ptrA)

MANN:

GM695_01255

APL:	APL_1883(ptrA)

APJ:	APJL_1926(ptrA)

APA:	APP7_1970(ptrA)

ASI:	ASU2_08060

ASS:	ASU1_08130

AEU:	ACEE_08530

APOR:

DDU33_04125

AIO:	EXH44_05995

ALIG:

NCTC10568_02299(ptrA_1)

AGP:	NYR63_10535(ptrA)

AGK:	NYR60_06170(ptrA)

BTO:

WQG_2310

BTRE:

F542_19650

BTRH:

F543_21550

BTRA:

F544_1880

OOI:	A6A10_00845

FCL:	A4G17_03345

SKH:	STH12_00051(ptrA_1)

ILO:	IL2336(ptr)

ILI:	K734_11760

IPI:	CEW91_01410

IDI:	CWC33_07040

IDT:	C5610_12155

IAB:	K5X84_11095

LSD:	EMK97_11080

THAT:

H3N35_08820

TACT:

SG35_009095

TVD:	SG34_020105

PHA:

PSHAb0349

PTN:	PTRA_b0517

PSM:

PSM_B0418

PSEO:

OM33_19265

PIA:	PI2015_3437

PPHE:

PP2015_3366 PP2015_686

PBW:	D172_018975

PRR:	AT705_21575

PLZ:	S4054249_21880

PALN:

B0W48_00380

PPIS:

B1L02_18380 B1L02_19840

PEA:	PESP_b0612

PSPO:

PSPO_b0674

PART:

PARC_b0522

PTU:	PTUN_b0584

PNG:	PNIG_b0480

PTD:	PTET_b0525

PSEN:

PNC201_17685(ptrA3) PNC201_18680(ptrA4)

PDJ:	D0907_17970

PAGA:

PAGA_b0682

PCAR:

PC2016_3404

PXI:	J5O05_19890

PVB:	J5X90_20415

PSAZ:

PA25_33950(ptr)

PDV:	FFU37_19700

PFLI:

CTT31_20175

PMAZ:

R5H13_20350

GPS:

C427_4126

LAL:	AT746_17040

PIN:

Ping_3480

PSY:	PCNPT3_01280

CJA:	CJA_3166 CJA_3602

CEB:	B0D95_11725

CELL:

CBR65_15660

CEK:	D0B88_06720

CEG:	D0C16_13205

GIL:	NHM04_03585 NHM04_11200

PAQM:

E0F26_05520

RHH:	E0Z06_13075

PLEI:

Q9312_10095

KSD:	KS2013_715

GAP:	GAPWK_0917

GAQ:	RAM11_08990(ptrA)

FPP:	FPB0191_01768

ORB:	IPMB12_03140(ptrA)

NBL:	GJV52_09940

NWX:	CGZ65_04280

DBA:

Dbac_3079

DOA:	AXF15_03410

DESU:

NLA06_15355(ptrA)

» show all

Reference

1 [PMID:3534791]

Authors

Finch PW, Wilson RE, Brown K, Hickson ID, Emmerson PT

Title

Complete nucleotide sequence of the Escherichia coli ptr gene encoding protease III.

Journal

Nucleic Acids Res 14:7695-703 (1986)
DOI:10.1093/nar/14.19.7695

Sequence

[eco:b2821]

Reference

2 [PMID:3059494]

Authors

Affholter JA, Fried VA, Roth RA.

Title

Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III.

Journal

Science 242:1415-8 (1988)
DOI:10.1126/science.3059494

Reference

3 [PMID:1570301]

Authors

Becker AB, Roth RA.

Title

An unusual active site identified in a family of zinc metalloendopeptidases.

Journal

Proc Natl Acad Sci U S A 89:3835-9 (1992)
DOI:10.1073/pnas.89.9.3835

Reference

4 [PMID:1733942]

Authors

Ding L, Becker AB, Suzuki A, Roth RA.

Title

Comparison of the enzymatic and biochemical properties of human insulin-degrading enzyme and Escherichia coli protease III.

Journal

J Biol Chem 267:2414-20 (1992)

Reference

5 [PMID:7680857]

Authors

Anastasi A, Knight CG, Barrett AJ.

Title

Characterization of the bacterial metalloendopeptidase pitrilysin by use of a continuous fluorescence assay.

Journal

Biochem J 290 ( Pt 2):601-7 (1993)
DOI:10.1042/bj2900601

Other DBs

ExplorEnz - The Enzyme Database:

3.4.24.55

IUBMB Enzyme Nomenclature:

3.4.24.55

ExPASy - ENZYME nomenclature database:

3.4.24.55

BRENDA, the Enzyme Database:

3.4.24.55

CAS:	81611-78-1

DBGET integrated database retrieval system