KEGG   ENZYME: 3.4.24.76
Entry
EC 3.4.24.76                Enzyme                                 
Name
flavastacin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Hydrolyses polypeptides on the amino-side of Asp in -Xaa!Asp-. Acts very slowly on -Xaa!Glu
Comment
A zinc metalloendopeptidase in peptidase family M12 (astacin family), secreted by the bacterium Flavobacterium meningosepticum . The specificity is similar to that of EC 3.4.24.33, peptidyl-Asp metalloendopeptidase from Pseudomonas fragi but the two are reported to be structurally dissimilar
History
EC 3.4.24.76 created 2000
Orthology
K20138  flavastacin
Genes
PROE: H9L23_01390
EAO: BD94_1887
EMN: M876_06475
EEN: BBD30_17465
ELB: VO54_00855
EGO: BBD34_17625
EGM: AYC65_08910
ELZ: FCS00_01660
ELIZ: JCR23_17475
CARH: EGY05_19190
CCAU: EG346_09185
CGLE: NCTC11432_02804
CHRJ: CHRYMOREF3P_2382
 » show all
Reference
1  [PMID:7771796]
  Authors
Tarentino AL, Quinones G, Grimwood BG, Hauer CR, Plummer TH Jr
  Title
Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase.
  Journal
Arch Biochem Biophys 319:281-5 (1995)
DOI:10.1006/abbi.1995.1293
  Sequence
[ag:AAC41455]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.76
IUBMB Enzyme Nomenclature: 3.4.24.76
ExPASy - ENZYME nomenclature database: 3.4.24.76
BRENDA, the Enzyme Database: 3.4.24.76
CAS: 167973-66-2

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Gene (15)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (14)   
Protein sequence (55)   
   UniProt (54)   
   SWISS-PROT (1)   
DNA sequence (84)   
   GenBank (42)   
   EMBL (42)   
Protein domain (6)   
   InterPro (6)   
All databases (160)   

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