KEGG ENZYME: 3.5.1.105

ENZYME: 3.5.1.105

Entry

EC 3.5.1.105                Enzyme

Name

chitin disaccharide deacetylase;
chitobiose amidohydolase;
COD;
chitin oligosaccharide deacetylase;
chitin oligosaccharide amidohydolase;
2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase

Class

Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides

Sysname

N,N'-diacetylchitobiose acetylhydrolase

Reaction(IUBMB)

N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate [RN:R11889]

Reaction(KEGG)

R11889

Substrate

N,N'-diacetylchitobiose [CPD:C01674];
H2O [CPD:C00001]

Product

N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine [CPD:C21747];
acetate [CPD:C00033]

Comment

Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains. Besides being a nutrient, the heterodisaccharide product 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus [2]. In contrast to EC 3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide [1,3]. It also deacetylates the chitin trisaccharide with lower efficiency [3]. No activity with higher polymers of GlcNAc [1,3].

History

EC 3.5.1.105 created 2010

Orthology

K03478

chitin disaccharide deacetylase

K18454

chitin disaccharide deacetylase

Genes

ECO:	b1733(chbG)

ECJ:	JW1722(chbG)

ECD:	ECDH10B_1871(chbG)

EBW:	BWG_1546(chbG)

ECOK:

ECMDS42_1408(chbG)

ECOC:

C3026_09905

ECE:	Z2763(ydjC)

ECS:	ECs_2439(chbG)

ECF:	ECH74115_2451

ETW:	ECSP_2301(chbG)

ELX:	CDCO157_2273

EOI:	ECO111_2244(chbG)

EOJ:	ECO26_2508(chbG)

EOH:	ECO103_1926(chbG)

ECOO:

ECRM13514_2230(ydjC)

ECOH:

ECRM13516_2135(ydjC)

ESL:

O3K_11300

ESO:

O3O_14320

ESM:

O3M_11280

ECK:	EC55989_1901(chbG)

ECG:	E2348C_1861(chbG)

EOK:	G2583_2179(chbG)

ELR:	ECO55CA74_10460

ELH:

ETEC_1765

ECW:	EcE24377A_1954

EUN:	UMNK88_2197

ECP:

ECP_1679

ENA:	ECNA114_1778(ydjC)

ECOS:

EC958_1954(ydjC)

ECV:	APECO1_802(ydjC)

ECOA:

APECO78_12495

ECX:	EcHS_A1815

ECM:	EcSMS35_1458

ECY:

ECSE_1903

ECR:	ECIAI1_1793(chbG)

ECQ:	ECED1_1935(chbG)

EUM:	ECUMN_2022(chbG)

ECT:	ECIAI39_1321(chbG)

EBR:	ECB_01702(ydjC)

ECOB:

C3029_13055

EBL:	ECD_01702(chbG)

EBE:	B21_01690(chbG)

EBD:

ECBD_1912

ECI:	UTI89_C1926(ydjC)

EIH:	ECOK1_1853

ECZ:	ECS88_1785(chbG)

ECC:	c2132(ydjC)

ELO:	EC042_1898(chbG)

ELN:	NRG857_08680

ESE:

ECSF_1594

ECL:	EcolC_1899

EKO:	EKO11_2042

EKF:	KO11_14070

EAB:	ECABU_c19890(ydjC)

EDH:	EcDH1_1909

EDJ:	ECDH1ME8569_1677(chbG)

ELU:	UM146_08485

ELW:	ECW_m1902(chbG)

ELL:

WFL_09325

ELC:	i14_1952(ydjC)

ELD:	i02_1952(ydjC)

ELP:	P12B_c1350

ELF:	LF82_0294(chbG)

ECOL:

LY180_09020

ECOI:

ECOPMV1_01831

ECOJ:

P423_09225

EFE:	EFER_1334(chbG)

EAL:	EAKF1_ch0715c EAKF1_ch4318

EMA:	C1192_03630

ESZ:	FEM44_18280(chbG) FEM44_23595(chbG)

ERUY:

OSH18_03390(chbG)

STY:

STY1796

STT:

t1196

SEX:	STBHUCCB_12850

SENT:

TY21A_06080

STM:	STM1317(celG)

SEO:	STM14_1599(celG)

SEV:	STMMW_13241

SEY:	SL1344_1252(celG)

SEM:	STMDT12_C13340

SEJ:	STMUK_1284(celG)

SEB:	STM474_1322(chbg)

SEF:	UMN798_1374

SETU:

STU288_02910

SETC:

CFSAN001921_10570

SENR:

STMDT2_12501

SEND:

DT104_12931

SENI:

CY43_06705

SEEN:

SE451236_12450

SPT:	SPA1527(celG)

SEK:

SSPA1418

SPQ:	SPAB_02023

SEI:	SPC_2413(celG)

SEC:	SCH_1338(celG)

SEH:	SeHA_C1446

SHB:

SU5_01936

SENH:

CFSAN002069_02420

SEEH:

SEEH1578_15815

SEE:	SNSL254_A1431

SENN:

SN31241_23920

SEW:	SeSA_A1414

SEA:	SeAg_B1854

SENS:

Q786_08670

SED:

SeD_A2027

SEG:

SG1799

SEL:

SPUL_1134

SEGA:

SPUCDC_1134

SET:

SEN1726

SENA:

AU38_08935

SENO:

AU37_08940

SENV:

AU39_08945

SENQ:

AU40_09985

SENL:

IY59_09140

SENJ:

CFSAN001992_05010

SEEC:

CFSAN002050_12985

SEEB:

SEEB0189_012945

SEEP:

I137_05210

SENB:

BN855_13540

SENE:

IA1_06500

SENC:

SEET0819_13235

SES:	SARI_01661 SARI_02170

SBG:

SBG_1171

SBZ:

A464_1272

SBV:	N643_05585

SALZ:

EOS98_12880

SFL:	SF1495(ydjC)

SFX:	S1612(ydjC)

SFV:	SFV_1487(ydjC)

SFN:

SFy_2144

SFS:

SFyv_2196

SFT:	NCTC1_01612

SSN:	SSON_1425(ydjC)

SHQ:	A0259_12720

ENC:

ECL_02434

ENL:	A3UG_09090

ECLG:

EC036_17530

ECLE:

ECNIH2_09700

ECLN:

ECNIH4_13570

ECLI:

ECNIH5_08770

ECLX:

LI66_09075

ECLY:

LI62_09850

ECLZ:

LI64_09140

ECLO:

ENC_14330

EHM:	AB284_15950

EXF:	BFV63_09110

ECLA:

ECNIH3_08780

ECLC:

ECR091_08755

EAU:	DI57_09815

EKB:	BFV64_09180

ENO:	ECENHK_09085

EEC:	EcWSU1_01795(ydjC)

ELG:	BH714_05315

ECAN:

CWI88_13340

ERN:	BFV67_08630

ECLS:

LI67_010135

ECHG:

FY206_10485(chbG)

ESH:	C1N69_09230

EPT:	HWQ17_03670(chbG)

ENT:	Ent638_1711

EAS:	Entas_1729

ENR:	H650_10060

ENX:	NI40_009205

ENF:	AKI40_1012

LNI:	CWR52_03100

EBG:	FAI37_20255(chbG)

END:	A4308_13775

ENZ:	G0034_08900(chbG)

ENS:	HWQ15_17225(chbG)

ENK:	LOC22_19485(chbG)

EHU:	D5067_0013645(chbG)

EMOR:

L6Y89_08770(chbG)

ENB:	ELK40_09440

EQU:	OM418_08770(chbG)

EPU:	QVH39_09250(chbG)

KPN:	KPN_01235(ydjC)

KPU:

KP1_2268

KPM:	KPHS_21350

KPP:

A79E_2951

KPH:	KPNIH24_17955

KPZ:	KPNIH27_10380

KPV:	KPNIH29_10895

KPW:	KPNIH30_11140

KPY:	KPNIH31_10520

KPG:	KPNIH32_10980

KPC:	KPNIH10_10575

KPQ:	KPR0928_10745

KPT:	VK055_1222

KPO:	KPN2242_09295

KPR:

KPR_2284

KPJ:

N559_3045

KPI:	D364_06400

KPA:	KPNJ1_03273

KPS:	KPNJ2_03264

KPX:	PMK1_03614

KPB:	FH42_02040

KPNE:

KU54_015520

KPNU:

LI86_15830

KPNK:

BN49_2371

KVA:

Kvar_3079

KPE:

KPK_3206

KPK:	A593_20905

KVD:	KR75_18750

KVQ:	SP68_25195

KOX:

KOX_18220

KOE:

A225_2500

KOY:	J415_19405

KOM:	HR38_16510

KMI:	VW41_07750

KOK:	KONIH1_12015

KOC:	AB185_23980

KQU:	AVR78_15570

EAE:

EAE_21530

EAR:

CCG29631

KQV:	B8P98_16165

KLL:	BJF97_12565

KLW:	DA718_16410(chbG)

KAR:	LGL98_14815(chbG)

KGR:	JJJ10_16305(chbG)

KPAS:

LUW96_18590(chbG)

KLC:	K7H21_16305(chbG)

KLM:	BWI76_11750

REE:	electrica_02996

ROR:	RORB6_08490

RON:	TE10_12300

RPLN:

B1209_15835

RAO:	DSD31_15070

RTG:	NCTC13098_04195

CRO:	ROD_07511(chbG) ROD_13231(chbG)

CKO:

CKO_01758

CFD:	CFNIH1_16555

CBRA:

A6J81_02750

CWE:	CO701_11690 CO701_15020

CYO:	CD187_13550

CPOT:

FOB25_01330(chbG)

CFQ:	C2U38_13540

CSED:

JY391_12240(chbG)

CAMA:

F384_05985

CAF:	AL524_16330

CIF:	AL515_10795

CFAR:

CI104_11860

CIR:	C2U53_21060

CIE:	AN232_19310

CPAR:

CUC49_06390

CTEL:

GBC03_18725(chbG)

CITZ:

E4Z61_03760(chbG)

CARS:

E1B03_11845(chbG)

CIX:	M4I31_13290(chbG)

CIB:	HF677_013255(chbG)

CENS:

P2W74_13240(chbG)

CNT:	JT31_04660

CEM:	LH23_13345

CEN:	LH86_12650

CLAP:

NCTC11466_02886

PGE:	LG71_18365

ESC:	Entcl_2543

KLE:	AO703_09535

KSA:	C813_20515

KOR:	AWR26_05150(chbG)

KRD:	A3780_18860

KPSE:

IP581_18370(chbG)

KOB:	HF650_19160(chbG)

KOO:	O9K67_05000(chbG)

KIE:	NCTC12125_01650(chbF_1)

KAS:	KATP_25780(chbG)

KLU:	K7B04_15630(chbG)

KCY:	RIN60_13095(chbG)

LAX:	APT61_13105

LEI:	C2U54_14635

LEH:	C3F35_02135

LEE:	DVA44_14170

LER:	GNG29_09480(chbG)

LEA:	GNG26_09140(chbG)

LPNU:

KQ929_11715(chbG)

LEY:	DVA43_08290

LAZ:	A8A57_08965

LEF:	LJPFL01_1740

LEW:	DAI21_17680

BUF:	D8682_07125

BAGE:

BADSM9389_26530

BFT:	MNO13_16050(chbG)

YRE:	HEC60_04235(chbG)

SGOE:

A8O29_013555(chbG)

KIN:	AB182_10180

PDZ:	HHA33_12790(chbG)

METY:

MRY16398_22490(chbG)

PSGC:

G163CM_15070(chbG)

SUPE:

P0H77_09970(chbG)

EBF:

D782_2540

EBC:	C2U52_20755

EBU:	CUC76_04520

YPE:

YPO2682

YPK:

y1255

YPH:

YPC_3176

YPA:

YPA_2411

YPN:

YPN_1168

YPM:

YP_2484

YPP:	YPDSF_1592

YPG:	YpAngola_A3572(chbG)

YPZ:

YPZ3_2366

YPT:	A1122_12665

YPD:

YPD4_2346

YPX:

YPD8_2345

YPW:

CH59_3562

YPJ:

CH55_1489

YPV:

BZ15_851

YPL:

CH46_2427

YPS:

YPTB2927

YPO:

BZ17_3701

YPI:	YpsIP31758_1095(chbG)

YPY:

YPK_1148

YPB:

YPTS_3043

YPQ:

DJ40_3562

YPU:

BZ21_2232

YPR:

BZ20_3245

YPC:

BZ23_2512

YPF:

BZ19_2298

YEN:

YE0972

YEP:	YE105_C3110

YEY:

Y11_42061

YEW:

CH47_375

YET:

CH48_630

YEF:	FORC2_0973

YSI:	BF17_01060

YAL:

AT01_3453

YFR:

AW19_126

YIN:

CH53_711

YKR:

CH54_1537

YRO:

CH64_1564

YRU:

BD65_607

YRB:	UGYR_03260

YMA:	DA391_05275

YHI:	D5F51_16715

YCA:	F0T03_05380(chbG)

YMO:	HRD69_20405(chbG)

YAS:	N0H69_08440(chbG)

YKI:	HRD70_09585(chbG)

YEG:	PL78_18060

SMAR:

SM39_0157(chbG)

SMAC:

SMDB11_0155(chbG)

SMW:	SMWW4_v1c08220(chbG)

SPE:

Spro_0838

SRR:	SerAS9_0762

SRL:	SOD_c07050(chbG)

SRY:	M621_03815

SPLY:

Q5A_003675(chbG)

SRS:	SerAS12_0762

SRA:	SerAS13_0762

SLQ:	M495_03530

SERF:

L085_00150

SERS:

SERRSCBI_03820

SQU:	E4343_12365(chbG)

SFJ:	SAMEA4384070_0872

SSUR:

ATE40_000755

SURI:

J0X03_19905(chbG)

SENP:

KHA73_03750(chbG)

SNEM:

NLX84_03850(chbG)

SNEV:

OI978_02545(chbG)

RAH:	Rahaq_4648

RACE:

JHW33_23515(chbG)

RAQ:	Rahaq2_4644

RAA:

Q7S_23761

RVC:	J9880_22855(chbG)

RBON:

QNM34_09535(chbG)

RIU:	I2123_23140(chbG)

EAME:

GXP68_18095(chbG)

PMR:	PMI2951(chbG)

PMIB:

BB2000_2961

PVL:	AOB99_15990

PVG:	CRN77_04870

PHAU:

PH4a_06305

PROT:

BTA34_16100

PCOL:

F1325_18325(chbG)

PCIB:

F9282_18900(chbG)

PPEE:

I6G31_10405(chbG)

PSI:

S70_15160

PSX:

DR96_265

PSTA:

BGK56_17950

PTHA:

OI982_07630(chbG)

PRG:	RB151_035220

PHEI:

NCTC12003_03031

PRQ:	CYG50_20885(chbG)

PVC:	G3341_15470(chbG)

PMAG:

JI723_15620(chbG)

PHAG:

PZ638_15795(chbG)

HAV:	AT03_21380

OPO:	DSM2777_04035

VCH:

VC_1280

VCF:	IR04_11700

VCS:

MS6_1061

VCE:	Vch1786_I0784

VCQ:	EN18_09690

VCJ:	VCD_003070

VCI:

O3Y_05955

VCO:	VC0395_A0899

VCR:	VC395_1399

VCM:	VCM66_1235

VCL:	VCLMA_A1124

VCX:	VAA049_1513

VCZ:	VAB027_1956

VVU:

VV1_1481

VVY:

VV2902

VVM:	VVMO6_00409

VVL:	VV93_v1c26080

VPA:

VP2638

VPB:

VPBB_2458

VPK:	M636_08635

VPF:	M634_15705

VPH:	VPUCM_2722

VHA:	VIBHAR_03626

VCA:	M892_13060

VAG:

N646_1731

VEX:	VEA_002434

VDB:	AL552_21990

VOW:	A9237_10560

VMI:	AL543_15755

VNL:	D3H41_14360

VPL:	SA104470976_01025

VTI:	CEQ48_12325

VMT:	QYQ96_07490(cod)

PPR:	PBPRA0494(VC1280)

PSHH:

HU773_012320(chbG)

SBL:

Sbal_1411

SBM:	Shew185_1402

SBN:	Sbal195_1438

SBP:	Sbal223_2943

SBT:	Sbal678_1473

SBS:	Sbal117_1519

SBB:	Sbal175_2925

SWD:

Swoo_0564

SHEW:

CKQ84_00710

SOG:	RA178_15350

AVR:

B565_2907

AEM:	CK911_11300

ARV:	C7N77_07040

AALL:

I6G90_00465(chbG)

ARIV:

KYK33_06250(chbG)

PGIN:

FRZ67_03560

HWS:	RNZ46_14260

» show all

Reference

1 [PMID:17334758]

Authors

Kadokura K, Rokutani A, Yamamoto M, Ikegami T, Sugita H, Itoi S, Hakamata W, Oku T, Nishio T

Title

Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin.

Journal

Appl Microbiol Biotechnol 75:357-65 (2007)
DOI:10.1007/s00253-006-0831-6

Reference

2 [PMID:19553519]

Authors

Hirano T, Kadokura K, Ikegami T, Shigeta Y, Kumaki Y, Hakamata W, Oku T, Nishio T

Title

Heterodisaccharide 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes.

Journal

Glycobiology 19:1046-53 (2009)
DOI:10.1093/glycob/cwp088

Sequence

[vha:VIBHAR_03626]

Reference

Authors

Ohishi, K., Yamagishi, M., Ohta, T., Motosugi, M., Izumida, H., Sano, H., Adachi, K., Miwa, T.

Title

Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8.

Journal

Biosci Biotechnol Biochem 61:1113-1117 (1997)

Reference