KEGG ENZYME: 3.5.1.125

ENZYME: 3.5.1.125

Entry

EC 3.5.1.125                Enzyme

Name

N2-acetyl-L-2,4-diaminobutanoate deacetylase;
doeB (gene name)

Class

Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides

Sysname

(2S)-2-acetamido-4-aminobutanoate amidohydrolase

Reaction(IUBMB)

(2S)-2-acetamido-4-aminobutanoate + H2O = L-2,4-diaminobutanoate + acetate [RN:R09801]

Reaction(KEGG)

R09801

Substrate

(2S)-2-acetamido-4-aminobutanoate [CPD:C19929];
H2O [CPD:C00001]

Product

L-2,4-diaminobutanoate [CPD:C03283];
acetate [CPD:C00033]

Comment

The enzyme, found in bacteria, has no activity with (2S)-4-acetamido-2-aminobutanoate (cf. EC 3.5.4.44, ectoine hydrolase).

History

EC 3.5.1.125 created 2017

Pathway

ec00260

Glycine, serine and threonine metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K15784

N2-acetyl-L-2,4-diaminobutanoate deacetylase

Genes

CAMA:

F384_12940

IZH:	FEM41_17290(doeB)

SMAF:

D781_2282

SRZ:	AXX16_2865

SERM:

CLM71_11805(doeB)

SRHZ:

FO014_21985(doeB)

VAG:

N646_3800

VEX:	VEA_000633

VDB:	AL552_04810(doeB)

VNA:	PN96_17660

VEJ:	VEJY3_17221

VNL:	D3H41_20750(doeB)

VKA:	BTD91_20445(doeB)

GHO:	AL542_02295(doeB)

GKD:	K6Q96_19905(doeB)

SALY:

E8E00_14715(doeB)

SKS:	FCN78_14015(doeB)

SCOT:

HBA18_14655(doeB)

SPRO:

N7E60_16585(doeB)

PAP:	PSPA7_4379(eutE)

PMK:

MDS_0057

PFUW:

KF707C_22190

PCQ:	PcP3B5_00240

PMUI:

G4G71_02700(doeB)

PNT:	G5B91_00110(doeB)

PPAA:

B7D75_20035(doeB)

PPU:

PP_4423

PPT:

PPS_0720

PPI:

YSA_00597

PPUH:

B479_04045

PPUD:

DW66_0727 DW66_1176

PFV:	Psefu_0030

PMON:

X969_02020

PMOT:

X970_02010

PPJ:	RK21_04288

PIX:	RIN61_15560(doeB)

PFE:	PSF113_4815

PMAN:

OU5_4502(eutE)

PCG:	AXG94_20240

PMUD:

NCTC8068_04704

PBA:	PSEBR_a4652

PBC:	CD58_05100

PDR:	H681_00260

PALL:

UYA_00165

PUM:	HGP31_27395(doeB)

PLAL:

FXN65_00115(doeB)

PSEJ:

HNQ25_01230(doeB)

PKH:	JLK41_00145(doeB)

PTY:	JWV26_10525(doeB)

PMAO:

PMYSY11_0799(doeB)

PANH:

HU763_003785(doeB)

PALV:

KSS97_05935(doeB)

PZA:	HU749_024490(doeB)

PTAE:

NCTC10697_00681

PCAS:

LOY40_04875(doeB)

PASI:

LG197_08820(doeB)

PCHE:

QYM18_07830(doeB)

PRHZ:

CRX69_08890(doeB)

PSTT:

CH92_00110

PDEN:

F1C79_24710(doeB)

APRS:

BI364_02915

AAEO:

BJI67_03370

AFY:	BW247_06495

GAI:	IMCC3135_09910(doeB_2) IMCC3135_32270(doeB_4)

CSA:

Csal_2731

CCAG:

SR908_04580(doeB)

HEL:	HELO_3664(doeB)

HCS:	FF32_01825

HAK:	KO116_01204

HAM:

HALO1224

HHU:	AR456_15080

HCO:	LOKO_00472

HSI:	BOX17_04120

HALO:

BWR19_14480

HHH:	CLM76_01775(doeB)

HBE:	BEI_2958(doeB)

HAG:	BB497_00060

HAF:	C8233_14550(doeB)

HMD:	CTT34_14380(doeB)

HAXI:

HAALTHF_21770n

HSV:	HNO53_16350(doeB)

HPRO:

LMS44_16950(doeB)

HQD:	K1Y77_13165(doeB)

HBH:	E4T21_15335(doeB)

HBP:	HPTD01_1999

HALF:

QEN58_14755(doeB)

HHAO:

QWG60_03445(doeB)

HASO:

B2G49_12680

HALW:

B6N23_13820(doeB)

HASH:

HXW73_13875(doeB)

HPIS:

P1P91_12265(doeB)

HALK:

CUU95_10310(doeB)

HVN:	EI420_15840(doeB)

HOL:	HORIV_52440

HSR:	HSBAA_50400

HPIZ:

GYM47_13610(doeB)

HNP:	SR894_15335(doeB)

HTT:	HZS52_10960(doeB)

HCAM:

I4484_15855(doeB)

HSX:	HNO51_15780(doeB)

HTX:	EKK97_17865(doeB)

HAA:	A5892_06420

CAMH:

LCW13_14025(doeB)

COBE:

CLAM6_28550

COBB:

H2O77_14430(doeB)

KUS:	B9G99_10905

KMA:	B9H00_03895

KUY:	FY550_04110(doeB)

PAUR:

FGL86_17270(doeB)

SAJS:

QO259_02885(doeB)

ABO:

ABO_0179

ALN:	AS19_01850

ALCA:

ASALC70_02204(doeB_2)

ADI:

B5T_00168

AXE:

P40_00825

OCE:

GU3_08060

ZDF:	AN401_02315

TSN:	W908_05910

THIN:

CRN91_04520(doeB)

BVI:	Bcep1808_5461

BCM:	Bcenmc03_6647

BCH:	Bcen2424_6166

BCJ:

BCAS0028

BCEN:

DM39_6670(eutE)

BCEW:

DM40_5478(eutE)

BCEO:

I35_7027

BAM:

Bamb_6021

BAC:	BamMC406_5777

BMJ:	BMULJ_05388

BMU:

Bmul_6142

BMK:	DM80_6598(eutE)

BMUL:

NP80_5359(eutE)

BCED:

DM42_6399(eutE)

BDL:	AK34_5361(eutE)

BDF:	WI26_29880

BLAT:

WK25_18055

BTEI:

WS51_29685

BPSL:

WS57_18490

BAEN:

L3V59_38205

BUG:	BC1001_4310

BGF:	BC1003_5086

BYI:	BYI23_B003720(eute)

BUE:	BRPE67_BCDS06290(eute)

BUQ:	AC233_27925

BGP:	BGL_1c21000

BPLA:

bpln_1g19430

BXE:

Bxe_C0058

BXB:	DR64_8367(eutE)

BPH:

Bphy_3861

BGE:	BC1002_4847

BPX:	BUPH_00895

BFN:	OI25_3931(eutE)

BCAI:

K788_0000261

PSPW:

BJG93_22455(doeB)

PARA:

BTO02_27260

PTER:

C2L65_27870(doeB)

PGP:	CUJ91_28290(doeB)

PTS:	CUJ90_21840(doeB)

PEW:	KZJ38_29860(doeB)

PSAA:

QEN71_14695(doeB) QEN71_40240 QEN71_40290

PPAI:

E1956_34440(doeB)

PPK:	U875_08125

PPNO:

DA70_00835

PPNM:

LV28_05480

PRB:	X636_01500

PSPU:

NA29_09675

PVE:	UC34_18660

PCOM:

NTU39_19965(doeB)

CABA:

SBC2_38080(doeB)

BUO:	BRPE64_BCDS09540

CABK:

NK8_38200(doeB)

TCAR:

U0034_21960(doeB)

BTRM:

SAMEA390648703342

BGV:	CAL12_10295

ADY:	HLG70_08560

APES:

FOC84_08925

AAEG:

RA224_28930

PARK:

LSG25_19950

VEI:

Veis_2148

MFLA:

GO485_28205

APET:

ToN1_21110(doeB)

ACOM:

CEW83_01830(doeB)

MLO:	mlr6093 mlr7142

MLN:	A9174_29920 A9174_31390 A9174_31775

MCI:	Mesci_2508 Mesci_5716

MCIC:

A4R28_21450 A4R28_29725

MOP:	Mesop_5920 Mesop_6295

MAM:	Mesau_05392 Mesau_05768

MAMO:

A6B35_24250

MESW:

A9K65_013115 A9K65_030885 A9K65_031155

MESM:

EJ066_28920(doeB)

MESP:

C1M53_04390(doeB)

MHUA:

MCHK_0653(doeB)

MJR:	EB229_30505(doeB) EB229_32015(doeB) EB229_32460

MERD:

EB233_26605(doeB)

MESR:

FGU64_08285(doeB)

MOH:	IHQ72_14430(doeB)

MMEI:

LRP31_10325 LRP31_14700(doeB)

HOE:	IMCC20628_03271

ANJ:	AMD1_3058 AMD1_PA0056

PHYL:

HB779_21165(doeB)

RPOD:

E0E05_14120(doeB) E0E05_16220

ORM:	HTY61_13215(doeB)

KMN:	HW532_08410 HW532_10925(doeB)

SME:	SM_b20435(eutE)

SMK:	Sinme_3745

SMQ:	SinmeB_4241

SMX:	SM11_pD1187(eutE)

SMI:	BN406_06239

SMEG:

C770_GR4pD1176

SMEL:

SM2011_b20435(eutE)

SMER:

DU99_31135

SMD:

Smed_3692

RHI:	NGR_b23240

SFH:	SFHH103_04918

SFD:	USDA257_c31400

SIX:	BSY16_5543(eutE)

SAME:

SAMCFNEI73_pC1834

SINO:

SS05631_b62070

ESJ:	SJ05684_b43250

EAK:	EKH55_4171

EMX:	FKV68_31035(doeB) FKV68_31710(doeB)

ENU:	PYH37_000809(doeB)

EGI:	PZN02_004772(doeB)

SKM:	PZL22_001197(doeB)

STEG:

QA637_24530(doeB)

EAD:	OV14_b1417

EAH:	FA04_31175

ECAA:

J3R84_33410(doeB)

ENP:	JVX98_30215(doeB)

ATU:

Atu4756

ATA:	AWN88_05990

AGR:	AGROH133_09406

ATF:	Ach5_44880(doeB)

AGT:	EYD00_19135(doeB)

ASAL:

CFBP5507_15250(doeB)

RIR:	BN877_II1095

RPUS:

CFBP5875_19345(doeB)

ACUC:

KZ699_23815(doeB)

ALEG:

CFBP4996_25085(doeB)

RET:	RHE_PF00179

REC:	RHECIAT_PC0000373

REL:	REMIM1_PF00737(eutE)

REP:	IE4803_PC00198(eutE)

REI:	IE4771_PD00199(eutE)

RLE:

pRL120055

RLT:	Rleg2_5522

RLG:

Rleg_5243

RLB:	RLEG3_09345

RLU:	RLEG12_04780

RTR:	RTCIAT899_PC08135(eutE)

RHL:	LPU83_pLPU83d1325(eutE)

RGA:	RGR602_PC02174(eutE)

RHN:	AMJ98_PE00273(eutE)

RPHA:

AMC79_PD00406(eutE)

RHX:	AMK02_PD00139(eutE)

RHV:	BA939_21240

RHK:	Kim5_PC00183(eutE)

REZ:	AMJ99_PD00273(eutE)

RJG:	CCGE525_32195(doeB)

RHR:	CKA34_29660(doeB)

RAD:	CO657_26060(doeB)

ROY:	G3A56_16945(doeB)

RHID:

FFM81_023125(doeB)

RBQ:	J2J99_22095(doeB)

RLN:	J0663_22885(doeB)

RBAN:

J2J98_21080(doeB)

RRG:	J3P73_24740(doeB)

RAW:	NE851_32105(doeB)

RSUL:

N2599_20840(doeB)

RLW:	RlegWSM1455_24200(doeB)

ARO:	B0909_16550(doeB)

NGL:	RG1141_PA13030(eutE)

NGG:	RG540_PA14010(eutE)

NEO:	CYG48_20835(doeB)

NPM:	QEO92_06315 QEO92_19400(doeB)

RHT:

NT26_3905

RFV:	RFYW14_03939

SHZ:

shn_23135

SOJ:	K6301_18980(doeB)

SSUM:

Q9314_20905(doeB)

KAI:

K32_40600

BRJ:	BKD03_11985

OIN:	IAR37_18910(doeB)

BIO:	BR141012304_10757

OAN:

Oant_3466

OAH:	DR92_3020(eutE)

OPS:	A8A54_16020

BPSN:

NIK97_13590(doeB)

OCH:	CES85_4624(eutE)

OCR:	HGK82_19820(doeB)

OCL:	GTN27_18045(doeB)

BOP:	AXW83_21155 AXW83_23735

BOS:	BSY19_1299

BVV:	BHK69_00420 BHK69_14640

BOI:	BLM15_05200 BLM15_23235

BOF:	FQV39_12920 FQV39_16740 FQV39_31510

BVES:

QO058_09730(doeB) QO058_10195 QO058_27775

LNE:	FZC33_33980(doeB)

APOL:

K9D25_11760(doeB)

MOC:	BB934_24605

MIV:	C4E04_03555 C4E04_10100(doeB)

CHEL:

AL346_21855

CDQ:	BOQ54_17550

DEQ:	XM25_03290

YTI:	FNA67_07120

MHAR:

L1P08_13010

AALA:

IGS74_01710(doeB)

AALM:

LUX29_03030(doeB)

AUZ:	Sa4125_45400

JIE:	OH818_05825(doeB)

JAV:	OXU80_20415(doeB)

NOH:	G5V57_02545 G5V57_19980 G5V57_20165 G5V57_24780

LABP:

FJ695_10255(doeB)

PSTG:

E8M01_28135

ACUT:

MRB58_12635(doeB)

SIL:	SPO1139(doeB)

SIT:	TM1040_2694

JAN:

Jann_0849

RDE:

RD1_3475

RLI:	RLO149_c026720

RPON:

G3256_07565(doeB)

OAR:	OA238_c23680(eutE) OA238_c32660

LMD:	METH_14370

LEJ:	ETW24_15265(doeB)

LAQU:

R2C4_20345(doeB)

LEV:	ETW23_14590(doeB)

LCAE:

K3721_19450(doeB)

CON:	TQ29_09650

SUAM:

BOO69_15090

SULD:

B5M07_16370

SPOT:

G6548_05615(doeB)

SMED:

JNX03_02430(doeB)

SINL:

DSM14862_03216(doeB_2)

SFAV:

PL335_15430(doeB)

SDUB:

R1T39_10230(doeB)

HAT:	RC74_18040

PLCG:

RVY76_17955

RSQ:	Rsph17025_3178

CAZT:

LV780_15615(doeB)

PDE:

Pden_0288

PYE:	A6J80_21900(doeB)

PZH:	CX676_02850(doeB)

PARO:

CUV01_01760(doeB)

PARS:

DRW48_07120(doeB)

PARR:

EOJ32_08980(doeB)

PKD:	F8A10_17630(doeB)

PLIA:

E4191_06425(doeB)

PSAN:

HGN31_00600(doeB)

PMAU:

CP157_01849(doeB)

PMEH:

JWJ88_19990(doeB)

PSEW:

JHW44_09320(doeB)

PSAP:

JHX88_09810(doeB)

PFIS:

JHX87_00885(doeB)

PAEX:

JHW48_07960(doeB)

PSTL:

JHW45_05775(doeB)

PALP:

JHW40_22420(doeB)

PVER:

E3U25_10985 E3U25_19240(doeB)

PAEZ:

PAE61_16475(doeB)

PALS:

PAF20_08305(doeB)

PDIM:

PAF18_11430(doeB)

PFEO:

E3U26_07275(doeB)

RMB:	K529_013150

TSCO:

R1T40_11905(doeB)

DAA:	AKL17_0185

DON:	BSK21_09535

LVS:	LOKVESSMR4R_00539(doeB)

SEDI:

EBB79_11110(doeB)

PPSO:

QPJ95_16115(doeB)

HML:	HmaOT1_18510(doeB)

LIT:	FPZ52_11030(doeB)

PAED:

G5B38_20865

MON:	G8E03_07585(doeB)

HDH:	G5B40_08310(doeB) G5B40_08680

GCE:	KYE46_04385

SINR:

O5O51_08250(doeB)

AMAQ:

GO499_04030(doeB)

RBX:	I3V23_11205(doeB)

HBA:

Hbal_0924

PALG:

HFP57_02015

ATI:	AL072_17690

HTQ:	FRZ44_47060

TXI:

TH3_02585

THAC:

CSC3H3_02840(doeB)

TII:	DY252_18735(doeB)

THAI:

IT893_02685(doeB)

TLU:	R1T41_11170(doeB)

TTB:	MACH01_05460

VSU:	P3M64_10365(doeB)

ELIO:

KO353_13105

SNEA:

NBZ79_05530(doeB)

PARH:

I5S86_22795(doeB)

NNV:	QNH39_12000

PBK:	Back11_62870

PSPN:

L1F29_06310

PAUN:

MJA45_09640

PPAB:

KET34_17550

PFAA:

MM59RIKEN_04930

BPRS:

CK3_07620

ETM:	CE91St48_29650

AHQ:	NMU03_07595

SJN:	RI060_39605

SCYN:

N8I84_06045 N8I84_36885

SKG:	KJK29_36500

ARE:	AL755_13110

ARH:	AHiyo8_41630

NMAR:

HPC71_11370

SPIQ:

OHA34_08535

SLOM:

PXH66_15215 PXH66_17165

MTAR:

DF168_01750(doeB)

RML:	FF011L_02920

RUV:

EC9_26760

AAGG:

ETAA8_28000 ETAA8_68890

SNEP:

Enr13x_21910

PLS:	VT03_13335

PLH:	VT85_21860

FMR:	Fuma_03204

GMR:	GmarT_14770

GIM:	F1728_07575

GPN:	Pan110_14140

GFM:	Enr17x_16290

PLON:

Pla110_12290

TPOL:

Mal48_29410

PVAR:

SH412_004336

GES:	VT84_20975

GMS:	SOIL9_12590

TIM:	GMBLW1_22480

ULI:	ETAA1_22410

SACI:

Sinac_6138

PBOR:

BSF38_00443(doeB)

AGV:	OJF2_70140

PFER:

IRI77_06400

NSO:	NIASO_04230

CAMU:

CA2015_2382

ECHI:

FKX85_16955

TPEL:

P0M28_27860

MARM:

YQ22_07400

AQD:	D1816_23735

AQE:	NBT05_02390

FLG:	LV716_16405

HAAD:

MW046_05110

NAY:	HYG81_00800

MEAM:

MU439_04650

» show all

Reference

1 [PMID:20849449]

Authors

Schwibbert K, Marin-Sanguino A, Bagyan I, Heidrich G, Lentzen G, Seitz H, Rampp M, Schuster SC, Klenk HP, Pfeiffer F, Oesterhelt D, Kunte HJ

Title

A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.

Journal

Environ Microbiol 13:1973-94 (2011)
DOI:10.1111/j.1462-2920.2010.02336.x

Sequence

[hel:HELO_3664]

Other DBs

ExplorEnz - The Enzyme Database:

3.5.1.125

IUBMB Enzyme Nomenclature:

3.5.1.125

ExPASy - ENZYME nomenclature database:

3.5.1.125

BRENDA, the Enzyme Database:

3.5.1.125

DBGET integrated database retrieval system