Entry
Name
N,N-dimethylformamidase;
dimethylformamidase;
DMFase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N,N-dimethylformamide amidohydrolase
Reaction(IUBMB)
N,N-dimethylformamide + H2O = dimethylamine + formate [RN:
R02509 ]
Reaction(KEGG)
Substrate
Product
Comment
An iron protein. Also acts on N-ethylformamide and N-methyl-formamide and, more slowly, on N,N-diethylformamide, N,N-dimethylacetamide and unsubstituted acyl amides.
History
EC 3.5.1.56 created 1989
Pathway
ec00630 Glyoxylate and dicarboxylate metabolism
Orthology
K03418 N,N-dimethylformamidase large subunit
K25305 N,N-dimethylformamidase small subunit
Genes
PAMN : JCM7685_0286(dmfA1)
Taxonomy
Reference
Authors
Schar HP, Holzmann W, Ramos Tombo GM, Ghisalba O.
Title
Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.56
ExPASy - ENZYME nomenclature database: 3.5.1.56