| Entry |
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| Name |
2-nitroimidazole nitrohydrolase;
NnhA;
2NI nitrohydrolase;
2NI denitrase
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| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In other compounds
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| Sysname |
2-nitroimidazole nitrohydrolase
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| Reaction(IUBMB) |
2-nitroimidazole + H2O = imidazol-2-one + nitrite [RN: R10133]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme catalyses the initial step in the biodegradation of 2-nitroimidazole by the soil bacterium Mycobacterium sp. JS330
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| History |
EC 3.5.99.9 created 2012
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| Orthology |
| K20764 | 2-nitroimidazole nitrohydrolase |
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| Genes |
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| Reference |
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| Authors |
Qu Y, Spain JC |
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| Title |
Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.5.99.9 |
| ExPASy - ENZYME nomenclature database: | 3.5.99.9 |
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