KEGG ENZYME: 3.6.1.68

ENZYME: 3.6.1.68

Entry

EC 3.6.1.68                 Enzyme

Name

geranyl diphosphate phosphohydrolase;
NUDX1 (gene name)

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

geranyl-diphosphate phosphohydrolase

Reaction(IUBMB)

geranyl diphosphate + H2O = geranyl phosphate + phosphate [RN:R11551]

Reaction(KEGG)

R11551

Substrate

geranyl diphosphate [CPD:C00341];
H2O [CPD:C00001]

Product

geranyl phosphate [CPD:C21203];
phosphate [CPD:C00009]

Comment

The enzyme, characterized from roses, is involved in a cytosolic pathway for the biosynthesis of free monoterpene alcohols that contribute to fragrance. In vitro the enzyme also acts on (2E,6E)-farnesyl diphosphate.

History

EC 3.6.1.68 created 2015 as EC 3.1.3.98, transferred 2016 to EC 3.6.1.68

Pathway

ec00902

Monoterpenoid biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K20986

geranyl diphosphate phosphohydrolase

Genes

FVE:	101310019 101310310

RCN:	112189710 112189741 112190176 112190349

PPER:

18792770

PMUM:

103341413

PAVI:

110757771

PDUL:

117615591 117615929 117617377 117617387

MDM:	103402740 103451694

MSYL:

126594874 126606456 126608658

PXB:	103929214 103946941

CSAV:

115698545

SSPL:

121767850 121770971

SHIS:

125216272

» show all

Reference

1 [PMID:26138978]

Authors

Magnard JL, Roccia A, Caissard JC, Vergne P, Sun P, Hecquet R, Dubois A, Hibrand-Saint Oyant L, Jullien F, Nicole F, Raymond O, Huguet S, Baltenweck R, Meyer S, Claudel P, Jeauffre J, Rohmer M, Foucher F, Hugueney P, Bendahmane M, Baudino S

Title

PLANT VOLATILES. Biosynthesis of monoterpene scent compounds in roses.

Journal

Science 349:81-3 (2015)
DOI:10.1126/science.aab0696

Sequence

[ag:AFW17224]

Other DBs

ExplorEnz - The Enzyme Database:

3.6.1.68

IUBMB Enzyme Nomenclature:

3.6.1.68

ExPASy - ENZYME nomenclature database:

3.6.1.68

BRENDA, the Enzyme Database:

3.6.1.68

DBGET integrated database retrieval system