KEGG ENZYME: 3.6.1.69

ENZYME: 3.6.1.69

Entry

EC 3.6.1.69                 Enzyme

Name

8-oxo-(d)GTP phosphatase;
mutT1 (gene name)

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

8-oxo-dGTP diphosphohydrolase

Reaction(IUBMB)

(1) 8-oxo-GTP + H2O = 8-oxo-GDP + phosphate [RN:R12532];
(2) 8-oxo-dGTP + H2O = 8-oxo-dGDP + phosphate [RN:R12533]

Reaction(KEGG)

R12532 R12533

Substrate

8-oxo-GTP [CPD:C22234];
H2O [CPD:C00001];
8-oxo-dGTP [CPD:C19967]

Product

8-oxo-GDP [CPD:C22235];
phosphate [CPD:C00009];
8-oxo-dGDP [CPD:C20176]

Comment

The enzyme, characterized from the bacterium Mycobacterium tuberculosis, catalyses the hydrolysis of both 8-oxo-GTP and 8-oxo-dGTP, thereby preventing transcriptional and translational errors caused by oxidative damage. The enzyme is highly specific. Unlike EC 3.6.1.55, 8-oxo-dGTP diphosphatase, it removes only a single phosphate group. The nucleoside diphosphate products are hydrolysed further by EC 3.6.1.58, 8-oxo-dGDP phosphatase.

History

EC 3.6.1.69 created 2019

Orthology

K23258

8-oxo-(d)GTP phosphatase

Genes

MSX:	AU14_09890

MPQ:	ABA45_04625

MSQ:	BKP64_09945

HMI:	soil367_13815

MICC:

AUP74_00379

STHM:

IS481_08525

MASW:

AM586_14985

MTIM:

DIR46_02805

TBD:

Tbd_2635

CFH:	C1707_20065

BDQ:	CIK05_11385

CLS:	CXIVA_06770

RUJ:	E5Z56_04050

THEP:

DYI95_006230

MTU:	Rv2985(mutT1)

MTV:

RVBD_2985

MTC:

MT3063

MRA:	MRA_3014(mutT1)

MTF:	TBFG_13000

MTB:	TBMG_00984

MTK:	TBSG_00991

MTZ:	TBXG_000975

MTI:	MRGA423_18555

MTE:	CCDC5079_2741

MTUR:

CFBS_3148(mutT1)

MTL:	CCDC5180_2706

MTO:	MTCTRI2_3044(mutT1)

MTD:	UDA_2985(mutT1)

MTN:	ERDMAN_3271(mutT1)

MTJ:	J112_15980

MTUB:

MT7199_3021(mutT1)

MTUC:

J113_20805

MTUE:

J114_15945

MTX:	M943_15375

MTUH:

I917_20960

MTUL:

TBHG_02915

MTUT:

HKBT1_3135(mutT1)

MTUU:

HKBT2_3140(mutT1)

MTQ:	HKBS1_3142(mutT1)

MBO:	BQ2027_MB3009(mutT1)

MBB:	BCG_3006(mutT1)

MBT:	JTY_3001(mutT1)

MBM:	BCGMEX_3002(mutT1)

MBK:	K60_030950

MBX:

BCGT_2825

MAF:	MAF_29900(mutT1)

MMIC:

RN08_3294

MCE:	MCAN_30071(mutT1)

MCQ:	BN44_60468(mutT)

MCV:	BN43_40693(mutT)

MCX:	BN42_40989(mutT)

MCZ:	BN45_51399(mutT)

MORY:

MO_003121

MLE:

ML1682

MLB:

MLBr01682

MPA:	MAP_3023(mutT1)

MAO:

MAP4_0777

MAVI:

RC58_03810

MAVU:

RE97_03815

MAV:

MAV_3835

MIT:

OCO_36550

MIA:

OCU_36590

MID:

MIP_05529

MYO:

OEM_37190

MCHI:

AN480_19310

MIR:

OCQ_37750

MMAL:

CKJ54_17305

MLP:

MLM_3045

MMAN:

MMAN_01280(mutT1)

MSA:	Mycsm_02260

MUL:	MUL_1971(mutT1)

MMI:	MMAR_1729(mutT1)

MMAE:

MMARE11_16480(mutT1)

MLI:	MULP_01885(mutT1)

MPSE:

MPSD_41110(mutT1)

MSHO:

MSHO_55160(mutT1)

MMC:

Mmcs_1924

MKM:

Mkms_1970

MJL:

Mjls_1904

MMM:

W7S_18285

MKN:	MKAN_23635

MYV:	G155_11500

MYE:	AB431_10475

MHAD:

B586_15615

MDX:	BTO20_23395

MSHG:

MSG_01588(mutT1)

MFJ:	MFLOJ_17170(mutT1)

MSTO:

MSTO_18830(mutT1)

MSIM:

MSIM_08160(mutT1)

MSAK:

MSAS_53350(mutT1)

MKU:	I2456_08805

MLW:	MJO58_08605

MXE:	MYXE_33810(mutT1)

MNV:	MNVI_31470(mutT1)

MPAG:

C0J29_10090

MNM:	MNVM_33620(mutT1)

MGOR:

H0P51_09485

MCOO:

MCOO_49480(mutT1)

MBAI:

MB901379_01542(mutT4_1)

MSEO:

MSEO_03990(mutT1)

MHEK:

JMUB5695_03351(mutT1)

MGAU:

MGALJ_05830(mutT1)

MLJ:	MLAC_29180(mutT1)

MBRD:

MBRA_48350(mutT1)

MSHJ:

MSHI_06930(mutT1)

MMAM:

K3U93_07635

MSPG:

F6B93_06990

MOT:	LTS72_16485

MPAA:

MKK62_16430

MMEH:

M5I08_05445

MKY:	IWGMT90018_18700(mutT1)

MADI:

A7U43_20345

MWU:	PT015_01535

MSM:	MSMEG_2390

MSG:	MSMEI_2330(mutT1)

MSB:	LJ00_11885

MSN:	LI99_11885

MSH:	LI98_11890

MVA:

Mvan_2138

MGI:

Mflv_4224

MSP:	Mspyr1_35670

MCB:	Mycch_1856

MNE:	D174_10715

MYN:	MyAD_10505

MFT:	XA26_23690

MPHL:

MPHLCCUG_02062(mutT4_1)

MVQ:

MYVA_2027

MLL:	B1R94_18660

MRH:	MycrhN_5893

MTHN:

4412656_01562

MHAS:

MHAS_00953(mutT1)

MDU:	MDUV_23880(mutT1)

MCHT:

MCHIJ_45860

MDR:	MDOR_13110(mutT1)

MAUU:

NCTC10437_01991

MMAG:

MMAD_21050(mutT1)

MMOR:

MMOR_43480(mutT1)

MFX:	MFAL_02180(mutT1)

MAIC:

MAIC_18040

MIJ:	MINS_20000

MALV:

MALV_15660

MTY:	MTOK_39580(mutT1)

MPSC:

MPSYJ_45260(mutT1)

MARZ:

MARA_19290(mutT1)

MGAD:

MGAD_18200(mutT1)

MHEV:

MHEL_42670(mutT1)

MSAR:

MSAR_48610(mutT1)

MANY:

MANY_03980

MAUB:

MAUB_54080(mutT1)

MPOF:

MPOR_24720

MPHU:

MPHO_15110(mutT1)

MMUC:

C1S78_010740

MMAT:

MMAGJ_53730

MBOK:

MBOE_51540

MFG:	K6L26_20835

MSEI:

MSEDJ_33450(mutT1)

MFLV:

NCTC10271_03401

MCEE:

MCEL_16330

MBRM:

L2Z93_001098

MMON:

EWR22_09770

MGO:	AFA91_27580

MHOL:

K3U96_17190

MSEN:

K3U95_18275

MPAE:

K0O64_10110

MRF:	MJO55_09645

MDF:	K0O62_10735

MCRO:

MI149_11000

MGRO:

FZ046_15800

MKR:	MKOR_17470(mutT1)

MPAK:

MIU77_12710

MAB:

MAB_3291

MMV:	MYCMA_1810

MABB:

MASS_3236

MABL:

MMASJCM_3298

MCHE:

BB28_16605

MIZ:	BAB75_17570

MSTE:

MSTE_03268

MSAO:

MYCSP_14995

MSAL:

DSM43276_03086(mutT4_1)

MJD:	JDM601_2688(mutT1)

MTER:

4434518_02634(mutT1)

MMIN:

MMIN_03880(mutT1)

MHIB:

MHIB_21200(mutT1)

MHER:

K3U94_15375

MVM:	MJO54_15325

ASD:

AS9A_3182

CGL:	Cgl1318(Cgl1318)

CGB:

cg1490

CGU:

WA5_1264

CGT:

cgR_1392

CGS:	C624_07395

CGG:	C629_07395

CGM:

cgp_1490

CGJ:

AR0_07100

CGQ:	CGLAR1_06965

CGX:	SB89_06810

CEF:

CE1429

CDI:

DIP1129

CDP:	CD241_1040

CDH:	CDB402_1004

CDT:	CDHC01_1040

CDE:	CDHC02_1039

CDR:	CDHC03_1034

CDA:	CDHC04_1045

CDZ:	CD31A_1141

CDB:	CDBH8_1112

CDS:	CDC7B_1051

CDD:	CDCE8392_1031

CDW:	CDPW8_1107

CDV:	CDVA01_1002

CDIP:

ERS451417_01044(mutT2)

CJK:

jk1219

CUR:

cu0776

CUA:	CU7111_0763

CAR:	cauri_1158

CKP:	ckrop_3002

CPU:	CPFRC_04590

CPL:	Cp3995_0927(mutT2)

CPG:	CP316_04730

CPP:	CpP54B96_0923(mutT2)

CPK:	CP1002_08555

CPQ:	CPC231_04590

CPX:	CPI19_06930

CPZ:	CpPAT10_0909(mutT2)

COR:	Cp267_0950(mutT2)

COP:	CP31_04960

COD:	Cp106_0896(mutT2)

COS:	Cp4202_0901(mutT2)

COI:	CPCIP5297_04750

COE:	CP258_04745

COU:	CP162_06525

CPSE:

CPTA_01476

CPSU:

CPTB_00056

CPSF:

CPTC_01468

CRD:

CRES_1313

CUL:	CULC22_00982

CUC:	CULC809_00967

CUE:	CULC0102_1087

CUN:	Cul210932_1015(mutT2)

CUQ:	Cul210931_0973(mutT2)

CUZ:	Cul05146_1040(mutT2)

CUJ:	CUL131002_0997c(mutT2)

CUS:	CulFRC11_0985(mutT2)

CVA:

CVAR_1748

CHN:	A605_06625

CCN:	H924_06100

CTER:

A606_07055

CMD:	B841_06145

CAZ:	CARG_04165

CFN:	CFAL_06755

CCG:	CCASEI_08045

CVT:	B843_06285

CGY:	CGLY_07130

CAX:	CATYP_05950

CII:	CIMIT_05440

CUV:	CUREI_05490

COA:

DR71_1960

CDO:	CDOO_06645

CHM:	B842_05875

CSX:	CSING_06435

CMQ:	B840_05500(mutT1)

CKU:	UL82_04345

CCJ:	UL81_05395

CMV:	CMUST_07265

CEI:	CEPID_05555

CTED:

CTEST_05860

CUT:	CUTER_04845

CLW:	CLAC_04990

CDX:	CDES_06375

CSP:

WM42_0197

CSTA:

CSTAT_07390

CCJZ:

ccrud_06435

CFK:	CFRA_06485

CPHO:

CPHO_06650

CFC:	CFLV_05620

CGV:	CGLAU_05800(mutT1)

CSTR:

CBE89_07720

CAQU:

CAQU_05665

CSPH:

CSPHI_04770

CAMG:

CAMM_07590

CMIN:

NCTC10288_01367

CPEG:

CPELA_06240(mutT1)

CXE:	FOB82_10340

CEE:	CENDO_05195(mutT1)

CSAN:

E3227_09935

CGK:	CGERO_04960(mutT1)

CRF:	FRC0190_01099

CRL:	NCTC7448_01800

CCHO:

CCHOA_05000(mutX)

CPRE:

Csp1_11160(mutT1)

CPSO:

CPPEL_06460(mutT1)

CSUR:

N24_1423

CCYS:

SAMEA4530656_1240

CMAT:

HBA49_12545

CYZ:	C3B44_06450

CKF:	I6I12_07395

CANS:

GP473_05645

CLIA:

C3E79_04905

CPRP:

I6I69_10360

CAMC:

I6I65_01215

CGLU:

I6J20_04395

CUO:	CUROG_06265(mutT1)

CLIZ:

G7Y31_05200

CSIL:

CBE74_05525

CTUB:

I6I74_10450

CLUJ:

IAU68_05310

CQN:	G7Y29_04835

CKW:	CKALI_04940(mutT1)

CCOE:

CETAM_05915(mutT1)

COK:	COCCU_06315(mutT1)

CZO:	IAU67_05585

CCYC:

SCMU_30510

CORY:

FQV43_04525

CMF:	GWO64_006820

CWK:	IA203_05885

CUW:	LH390_05170

CPOY:

GP475_05315

CACC:

CACC_05715(mutT2)

CFY:	I6L56_01170

CPSL:

KBP54_05260

CHIN:

J5O04_08965

CJH:	CJEDD_05900(mutT1)

CPSP:

L9H27_04705

CMAS:

CMASS_04735(mutT1)

CHEI:

CHEID_06370(nudG)

CIHU:

CIHUM_05100(mutT1)

CCOY:

CCOY_05830(mutT1)

CHAD:

CHAD_05625(mutT1)

CFG:	CFREI_05905(mutT2)

CAQM:

CAQUA_06495(mutT1)

CCAW:

CCANI_06230(mutT1)

CAUI:

CAURIS_05105(mutT1)

CFAC:

CFAEC_06285(mutT1)

CFOU:

CFOUR_05140(mutT1)

CFEU:

CFELI_05930

CAUS:

CAURIC_06645

CATR:

CATRI_05730(mutT1)

CDUR:

CDUR_05800(mutT1)

CCOU:

CCONF_05420(mutT1)

CHAN:

CHAN_05320(mutT1)

CAFE:

CAFEL_05020(mutT1)

CGF:	CGUA_06015(mutT1)

CGOI:

CGOTT_05325(mutT1)

CAPP:

CAPP_05335(mutT1)

CBOV:

CBOVI_04300(mutT1)

CSUE:

QP029_10240

CBRE:

QP027_04860

CPYR:

CYJ47_07070

CRIE:

AK829_04125

BFV:	C628_07240

NFA:

NFA_42090

NFR:	ERS450000_05706

NCY:	NOCYR_3928

NBR:	O3I_031690

NNO:	NONO_c56710

NSL:	BOX37_21885

NSR:	NS506_06552

NTP:	CRH09_28320

NOZ:	DMB37_10565

NOD:	FOH10_21715

NAH:	F5544_34245

NAD:	NCTC11293_05428

NWL:	NWFMUON74_20600

NIE:	KV110_30595

NTC:	KHQ06_34085

NHU:	H0264_33020

NYA:	LTV02_00975

NGP:	LTT66_22910

NSPU:

IFM12276_14370

NYU:	D7D52_16255

RHA:	RHA1_ro06502

RER:	RER_24110(mutT)

REY:

O5Y_11320

REB:	XU06_11530

RQI:	C1M55_12585

ROP:	ROP_02400 ROP_65530(mutT)

ROA:	Pd630_LPD03170

RPY:	Y013_06650

RBY:	CEJ39_17570

RHB:

NY08_1488

RAV:	AAT18_16280

RFA:	A3L23_04718(mutT1)

RHS:	A3Q41_03552(mutT1)

RHW:	BFN03_05420

RRZ:	CS378_05870

RHU:	A3Q40_01317(mutT1)

RHQ:	IM25_20670

RHOD:

AOT96_22795

RRT:	4535765_03148(nudG_2)

RCR:	NCTC10994_04098(nudG_2)

RTM:	G4H71_18830

RKO:	JWS14_35255

RGO:	KYT97_00005

ROZ:	CBI38_18270

RPSK:

JWS13_08670

RGOR:

NMQ04_13510

RANT:

RHODO2019_04260

RHOP:

D8W71_14795

REQ:

REQ_31330

PDEF:

P9209_13165

WHR:	OG579_05400

GBR:

Gbro_3212

GPO:	GPOL_c29910

GOR:

KTR9_3251

GOQ:	ACH46_14045

GTA:	BCM27_16545

GOC:	CXX93_08960

GIT:	C6V83_14110

GRU:	GCWB2_16730

GOM:	D7316_00060(mutT1)

GAV:	C5O27_11420

GOD:	GKZ92_15660

GAM:	GII34_15440

GPD:	GII33_14605

GJI:	H1R19_15595

GOI:	LK459_18345

GHN:	MVF96_16020

GAMI:

IHQ52_19530

GMG:	NWF22_01070

GSI:	P5P27_13290

SPIN:

KV203_12380

TPR:

Tpau_2845

TSM:	ASU32_15855

TPUL:

TPB0596_16340

SRT:

Srot_0986

DTM:	BJL86_1923

DIT:	C3V38_15195

DIZ:	CT688_09320

DPC:	A6048_09540

DLU:	A6035_09070

DKN:	NHB83_08900

CBQ:	AL705_01300

TOY:	FO059_10870

SFIC:

EIZ62_17520

LXL:	KDY119_03075

PSIC:

J4E96_01195

LEIF:

HF024_14065

LSE:	F1C12_20255

CMI:

CMM_2504

CMH:	VO01_12850

CMS:

CMS2728

CMC:

CMN_02457

CCAP:

AES38_12075

CZH:	H9X71_12460

CPHA:

FGI33_00775

CCAF:

FGD68_14815

MTS:

MTES_2719

MIM:	AKG07_07895

MIO:	AOA12_06760

MIX:	AB663_003386

MIP:	AXH82_01685

MCW:	A8L33_13660

MPAL:

BO218_00580

MIH:	BJP65_13930

MICR:

BMW26_12410

MAUR:

BOH66_05525

MHOS:

CXR34_05505

MFOL:

DXT68_12525

MOO:	BWL13_00859(mutT1)

MLV:	CVS47_02255(mutT1)

MWA:	E4K62_13300

MPRT:

ET475_01285

MSED:

E3O41_10310

MOY:	CVS54_02820(mutT1)

MSF:	IT882_12055

MCAW:

F6J84_03995

MLZ:	F6J85_12650

MCHN:

HCR76_11100

MRN:	K8F61_18780

MICS:

C1N74_10680

MBIN:

LXM64_04850

MLIQ:

NMQ05_13755

MTEC:

OAU46_04495

MPAO:

IZR02_12340

MAZA:

NFX31_12655

MELY:

L2X98_00035

MNF:	JSY13_09720

MSUW:

GCM10025863_01190

MARK:

QUC20_10585

MRG:	SM116_13945

MINV:

T9R20_06065

MEST:

PTQ19_11570

RLA:	Rhola_00003580

RPLA:

A4Z71_01530

AQG:	HRU87_01525

AQK:	AKACHI_10230

RTX:	TI83_03230

RTC:	APU90_03245

RTN:	A6122_0720

RRY:	C1O28_02470

RIA:	C7V51_08680

RFS:	C1I64_01425

RTE:	GSU10_11455

CUM:	NI26_14290

CUB:	BJK06_10165

CUG:	C1N91_14645

CCIT:

QPK07_14905

MVD:	AWU67_11045

FRP:	AX769_06755

FSB:	GCM10025867_14750

AGY:	ATC03_06165

AGM:	DCE93_10860

AGF:	ET445_07970

AARC:

G127AT_11725

AMAU:

DSM26151_22080(mutT1)

ASOI:

MTP13_10005

AMAV:

GCM10025877_06580

ALAV:

MTO99_09770

CART:

PA27867_2822

CRY:	B7495_13660

CPHY:

B5808_05280

AMIN:

AUMI_110590

AUM:	AURMO_01446

AUW:	AURUGA1_00278(mutT4)

PSAI:

C3B54_111712

MALK:

MalAC0309_2415

CHRE:

IE160_10560

MHUM:

NNL39_03245

MDB:	OVN18_02830

MYL:	C3E77_10900

MSPO:

KXZ72_12515

SALC:

C2138_01535

SALA:

ESZ53_06485

SALD:

FVA74_12025

HUM:	DVJ78_15610

HUW:	FPZ11_08500

GRY:	D7I44_04505

LYD:	D7I47_03655

LYK:	FLP23_04575

PLAP:

EAO79_09960

LEU:	Leucomu_02630

LTR:	EVS81_12415

LEB:	G7066_12705

LDN:	H9L06_09610

LVI:	G7068_06565

LINS:

G7067_00125

LLUT:

K1X41_12025

LALL:

MUN78_11720

LRP:	MUN76_13295

LTN:	KVY00_12415

AGG:	C1N71_11215

AGRO:

JSQ78_06350

MANT:

BHD05_05400

HEA:	HL652_01735

FRN:	F1C15_06620

GLN:	F1C58_13600

AGX:	AGREI_2323

SUBT:

KPL76_00355

SUBA:

LQ955_01540

PSEV:

USB125703_00322(mutT1)

GSD:	M3M28_09230

NAEI:

GCM126_07800

LYH:	FrondiHNR_04130

AOG:	LH407_04815

ART:

Arth_3015

ARR:	ARUE_c31360(mutT)

ARM:

ART_2165

ARL:	AFL94_12265

ARE:	AL755_18945

AAQ:	AOC05_12995

ARW:	MB46_13655

ARH:	AHiyo8_50150

ARY:	ATC04_05945

ARZ:	AUT26_14695

ARU:	ASPU41_01045

ARQ:	BWQ92_16325

ARN:	CGK93_17020

ARX:	ARZXY2_686

ACRY:

AC20117_01800

ARTH:

C3B78_14430

ARTP:

E5206_06860

AAGI:

NCTC2676_1_02370

AJG:	KKR91_13690

ASUN:

KG104_14585

ASUF:

MNQ99_04965

ARTY:

AHiyo4_37200

APOA:

J0916_12410

AWW:	G8758_10225

ACAO:

NF551_13015

AZH:	MUK71_12960

AGEG:

MUG94_13980

AOD:	Q8Z05_01955

AKO:	N9A08_12560

AZX:	N2K95_12900

AJR:	N2K98_13610

ARI:	UM93_10045

AAU:

AAur_2989

PUE:	FV140_16290

PNV:	JMY29_14400

ACH:

Achl_2727

APN:	Asphe3_28580

PSUL:

AU252_16630

PSNI:

NIBR502771_10655

PSEY:

GU243_09800

PDEL:

JCQ34_13745

POK:	SMD14_14710

AAI:	AARI_23830

GAR:	AOZ07_12265

GCR:	GcLGCM259_2119

GLU:	F0M17_11720

GPR:	JQN66_12215

GMI:	NMP99_12265

GMY:

XH9_13725

GNC:	QQS42_12000

RSA:	RSal33209_0964

KRH:	KRH_05700(mutT)

KPL:	KPaMU14_10095

KFV:	AS188_14235

KII:	KocCE7_02925

KOD:	HBK84_03125

KVR:	CIB50_0000119(mutT1)

MLU:	Mlut_17440

MICK:

B1A86_00008705

MYU:	M8233_08340

MLY:	CJ228_006330

MPOR:

KW076_05315

MTEU:

R3I42_07625

RMU:	RMDY18_04140

RDN:	HMPREF0733_10357

RAJ:	RA11412_2640

RTER:

IDM49_02960

RAMA:

IDM48_02865

RKR:	I6G21_01585

SATK:

SA2016_3069

NAE:	BHE16_11285

AUL:	DCC27_000190

AIG:	QDX25_12155

CMUA:

P8192_10920

PAEY:

KUF55_12510

PALU:

CJ193_007130

BCV:

Bcav_3427

BFA:	Bfae_25640

BRX:	BH708_09425

BRV:	CFK39_05365

BGG:	CFK41_03585

BRZ:	CFK38_05720

BSAU:

DWV08_10605

BRR:	C1N80_05820

BRHA:

NLU66_06625

DVA:	DAD186_18530

DJJ:	COP05_01790

DHM:	CYJ49_007425

HMM:	R3I40_00480

JDE:

Jden_2236

KSE:	Ksed_03520

DNI:	HX89_11905

DAY:	FV141_11125

DERM:

H7F30_06095

LMOI:

VV02_07145

YIM:	J5M86_12545

ALX:	LVQ62_06140

BEI:	GCM100_31600

XCE:	Xcel_0301 Xcel_1389

XYL:	ET495_14585

XYA:	ET471_07015

IVA:	Isova_0378

IDO:	I598_1984(ndx1)

CET:	B8281_00390

CCEU:

CBR64_11650

CPRT:

FIC82_018345

SKE:	Sked_33510

SANW:

G7063_13235

CFL:

Cfla_2816

CGA:	Celgi_2641

CEZ:	CBP52_10330

CELZ:

E5225_03665

CEJ:	GC089_03910

CELH:

GXP71_12290

CIRA:

LFM56_04010

CPAL:

F1D97_17140

CWN:	NP075_14620

CCHE:

NP064_14490

CXIE:

NP048_14255

OEK:	FFI11_006605

PSEI:

GCE65_14390

PSEK:

GCM125_08190

ICA:	Intca_2952

ARS:	ADJ73_01345

JTE:	ASJ30_01475

JLI:	EXU32_13900

JME:	EEW87_013615

JAY:	H7A72_01420

JCR:	O9K63_13980

TEH:	GKE56_14660

PHW:	G7075_13995

PEI:	H9L10_00050

TED:	U5C87_00375

SERJ:

SGUI_2592

SERW:

FY030_13325

ORZ:	FNH13_04135

ORD:	L0A91_09820

OCP:	NF557_02615

BLY:	A2T55_15185

BLIN:

BLSMQ_3337

BRI:	FDF13_05870

BLUT:

EW640_08275

BCAU:

I6G59_01090

BSPO:

L1F31_15720

DCO:	SAMEA4475696_0872

AUS:	IPK37_11145

GEZ:	FE251_14135

GYU:	FE374_16750

HALT:

IM660_16350

RHAL:

LQF10_16100

RSUA:

LQF12_14080

DEM:	LGT36_009850

DSS:	GCM25873_18940

PAC:

PPA0342

PAK:	HMPREF0675_3384

PAV:	TIA2EST22_01720

PAX:	TIA2EST36_01705

PAZ:	TIA2EST2_01640

PAW:	PAZ_c03600(mutT)

PAD:	TIIST44_06420

PCN:	TIB1ST10_01750

PACC:

PAC1_01760

PACH:

PAGK_0363

PACN:

TIA1EST1_01710

CACN:

RN83_02185

PRA:	PALO_08850

PRL:	BCB70_04785

CGRN:

4412665_00180

CEQU:

O6R08_01535

PFR:	PFREUD_19940

PFRE:

RM25_1902

PACD:

EGX94_08590

PAUS:

NCTC13651_02137

PPC:	HMPREF9154_0457

ARUB:

J5A65_02700

PBO:	PACID_27590

AACI:

ASQ49_08275

ACIJ:

JS278_00737(mutT1)

AJI:	C0Z10_02305

MPH:	MLP_47710(mutT)

MIK:	FOE78_22105

MICG:

GJV80_14290

TFA:	BW733_04510

TES:	BW730_00145

TEZ:	BKM78_11150

TDF:	H9L22_00095

TLA:	TLA_TLA_02245(mutT1)

RAIN:

Rai3103_10100

PRV:	G7070_04975

BRT:	J4N02_14055

PROP:

QQ658_10855

BROO:

brsh051_08180

NCA:

Noca_4264

NDK:	I601_1704(ndx1)

NOY:	EXE57_14545

NOI:	FCL41_01945

NOO:	FE634_18270

NDP:	E2C04_02550

NSN:	EXE58_10365

NBE:	Back2_14410

NANO:

G5V58_19680

NMES:

H9L09_06680

NARO:

CFH99_20830

NPI:	G7071_06915

NAQU:

ENKNEFLB_00723(mutT1_1)

NRO:	K8W59_15615

NOQ:	LN652_10660

NCQ:	K6T13_15415

NPC:	KUV85_16530

NMAR:

HPC71_18550

NFC:	KG111_15800

PSIM:

KR76_22975

AER:	AERYTH_14340

AEZ:	C3E78_02495

AEB:	C6I20_13390

AEF:	GEV26_02635

ASEZ:

H9L21_01325

ADB:	NP095_01350

AWN:	NQV15_02310

MGG:	MPLG2_3702

MUZ:	H4N58_02550

SGRG:

L0C25_13805

NBT:	KLP28_09340

KFL:

Kfla_0965

KQI:	F1D05_24870

KSL:	OG809_16405

TFU:

Tfu_0324

THAO:

NI17_022160

TALX:

FOF52_19330

NDA:

Ndas_5221

NAL:

B005_2821

NGV:	CDO52_05735

NEX:	NE857_06075

NAKE:

KGD83_25625

NCG:	KGD84_27570

STRR:

EKD16_02655

SNAH:

OUQ99_27130

TCU:

Tcur_0260

ACTW:

F7P10_22755

AGRA:

AGRA3207_003820

AMAZ:

LUW76_23660

ACIR:

OG979_16280

SPIQ:

OHA34_25305

ACTQ:

OG417_06705

SRO:

Sros_8612

NOA:	BKM31_50815

NOW:	GBF35_45275

NCX:	Nocox_37585(ndx1)

NGN:	LCN96_50565

NFS:	OIE67_53905

MHAI:

OHB01_05490

FRA:	Francci3_4501

FRI:	FraEuI1c_3693

NML:

Namu_1481

NAK:	EH165_10300

NAKA:

H7F38_21620

GOB:

Gobs_4051

BSD:	BLASA_3832

BLAP:

MVA48_21530

MMAR:

MODMU_4460

KRA:

Krad_0876

SEN:

SACE_6141

SACG:

FDZ84_05715

SVI:	Svir_09090

SACC:

EYD13_04950(mutT1)

AMD:

AMED_1727

AMN:

RAM_08770

AMM:

AMES_1714

AMZ:

B737_1715

AOI:

AORI_6143

AJA:	AJAP_08695(mutT1)

AMQ:	AMETH_1529

AMYC:

CU254_07035

AMYB:

BKN51_24240

AAB:	A4R43_19575

AMYY:

YIM_10170

AORI:

SD37_30115

AACD:

LWP59_07740

APRT:

MUY14_27820

AROO:

NQK81_35950

ATHM:

L1857_10295

ARHD:

VSH64_46705

PDX:

Psed_1835

PSEA:

WY02_10140

PSEE:

FRP1_04105

PSEH:

XF36_18730

PSEQ:

AD006_11765

PECQ:

AD017_19590

PHH:	AFB00_04050

PAUT:

Pdca_53320

PBRO:

HOP40_15235

PPEL:

H6H00_14745

APRE:

CNX65_29520

AMI:

Amir_6003

SESP:

BN6_71860(mutT1)

SSYI:

EKG83_40205

KAL:

KALB_7398

KUT:	JJ691_91960

KPHY:

AOZ06_45235

LED:	BBK82_21540

AHM:	TL08_22635

ACTI:

UA75_26415

ACAD:

UA74_25830

AHG:	AHOG_23730(mutT1)

ACTA:

C1701_06380

ALO:

CRK58731

PMAD:

BAY61_06405

SACE:

GIY23_17580

ACTU:

Actkin_04956(mutT4_1)

CROS:

N8J89_34265

ACTY:

OG774_11040

UME:	RM788_17245

STP:	Strop_1261

SAQ:

Sare_1152

MAU:	Micau_1333

MIL:

ML5_1579

MICB:

MicB006_1356

MTUA:

CSH63_17555

MICH:

FJK98_07035

MTEM:

GCE86_00790

MCAB:

HXZ27_07890

MSAG:

GCM10017556_39110

VMA:	VAB18032_11335

MCRA:

ID554_05265

VER:	HUT12_07675

MENO:

Jiend_14230

MCHL:

PVK74_27865

MFEU:

H1D33_13445

MPRN:

Q3V37_00420

MHAW:

RMN56_04795

ASE:

ACPL_7343

AMS:	AMIS_70920

ACTN:

L083_6934

AFS:

AFR_36675

ACTS:

ACWT_7213

AIH:	Aiant_31810(mutT1)

ACTR:

Asp14428_61160

ACTL:

L3i22_096670

ASIC:

Q0Z83_099200(mutT1) Q0Z83_108820

AOU:	ACTOB_007624

PLK:	CIK06_06900

PLAB:

C6361_25230

PLAT:

C6W10_13625

PFLA:

Pflav_085480

PSUU:

Psuf_048420

ATL:	Athai_22280 Athai_59040

ASER:

Asera_52650

PRY:	Prubr_39440

DVC:	Dvina_08095

DFU:	Dfulv_07510

DROS:

Drose_07820

DAUR:

Daura_07490

DMAT:

Dmats_07605

NHY:	JQS43_18705

CCAZ:

COUCH_07810

CAI:

Caci_8260

SNA:

Snas_4995

NAV:	JQS30_04095

GLY:	K3N28_11460 K3N28_13175 K3N28_20920

AWL:	P8A24_07655

ACAS:

P7079_07140

MCU:	HMPREF0573_10436

TPY:	CQ11_08945

TPYO:

X956_09250

TBW:	NCTC13354_01324

TPEC:

HLG82_08430

TBER:

QPC17_07660

ASG:	FB03_05700

ATIM:

CYJ17_0001325

ACTT:

DDD63_10150

AMY:	ADJ76_08645

SOO:	FBF35_09455

STUC:

G5S47_00695

ACQ:	AM609_11910

AOS:	AXE84_06720

ARD:	AXF14_06500

ACTO:

C3V41_12305

ANE:	ATCC27039_00060

AHW:	NCTC11636_01283

ACTZ:

CWT12_01655

AIR:	NCTC12972_01562

ASLA:

NCTC11923_00932

AVC:	NCTC10951_02741

AWE:	JG540_01685

AREP:

ID810_10480

AMAS:

QU670_02435

ACAP:

MANAM107_15110

AUO:	R3I39_01055

ALIL:

D5R93_02370

AVU:	BK816_08605

FSL:	EJO69_06920

FLH:	EJ997_07860

WIK:	H8R18_07945

GEU:	CJ185_008190

GHM:	CJ187_005955

VCB:	CYK25_000455

PHON:

BH719_05455

BLO:	BL1258(mutT1)

BLJ:	BLD_1592(mutT3)

BLN:

Blon_2329

BLON:

BLIJ_2405

BLF:

BLIF_1852

BLL:

BLJ_1856

BLB:	BBMN68_1517(mutT3)

BLM:

BLLJ_1771

BLK:	BLNIAS_00132

BLG:

BIL_05520

BLZ:	BLGT_09565

BLX:	GS08_09635

BAD:	BAD_0126(mutT1)

BADL:

BADO_0136

BADO:

BBMN23_0145

BLA:	BLA_0191(mutT)

BLC:	Balac_0202

BLT:	Balat_0202

BBB:

BIF_01427

BBC:

BLC1_0193

BNM:	BALAC2494_00920

BLV:

BalV_0197

BLW:

W7Y_0198

BLS:

W91_0202

BANI:

Bl12_0187

BANL:

BLAC_01050

BNI:	BANAN_01060

BANM:

EN10_01035

BDE:

BDP_0204

BDN:

BBDE_0192

BBP:

BBPR_1764

BBI:

BBIF_1706

BBF:	BBB_1762(mutT)

BBV:	HMPREF9228_1854

BBRU:

Bbr_1771

BBRE:

B12L_1704

BBRV:

B689b_1802

BBRJ:

B7017_1968

BBRC:

B7019_1941

BBRN:

B2258_1794

BBRS:

BS27_1767

BBRD:

BBBR_1776

BAST:

BAST_1554

BTP:

D805_0215

BCOR:

BCOR_1341

BKA:	AH68_00740

BKS:

BBKW_0139

BCAT:

BBCT_0120

BPSP:

AH67_01000

BII:	BINDI_1271

BANG:

BBAG_1380

BPSC:

BBPC_0135

BSCA:

BBSC_2348

BACT:

AB656_05220

BCHO:

BcFMB_03345

BGX:	ESN35_10015

BLEM:

BL8807_05460

BEU:	BE0216_06260

BSUE:

BS3272_09045

BFJ:	B19861_01210

GVG:	HMPREF0421_20086

GVA:	HMPREF0424_0081

GVH:	HMPREF9231_1366

GPT:	K9E43_03410

GSW:	K9E37_03525

SIJ:

SCIP_1325

PDO:

PSDT_0098

BAPK:

KIMH_14660

BNK:	KIM372_16920(mutT1)

AEY:	CDG81_06965

PLAN:

A1s21148_00575

PLAK:

A1s21155_01915

PLIM:

PHILAsVB114_00735

PSUF:

A1sIA56_01805

PVS:	A1sIA79_01625

PVN:	A7sIIA15_06350

ABAM:

B1s21122_05735

NHI:	B1s21160_05540

NAB:	B1sIIB91_05285

EKE:	EK0264_16935

JTL:	M6D93_08110

AFO:

Afer_1187

ATQ:	GH723_05130

AQZ:	KSP35_21990

RRS:	RoseRS_4563

MICA:

P0L94_01505

BBD:	Belba_2288

EVI:	Echvi_2215

EST:	DN752_16720

ECHI:

FKX85_10530

LBY:

Lbys_0044

HSW:

Hsw_2908

HYM:	N008_14860

HYD:	PK28_12680

HYE:	AM218_03775

HYG:	AUC43_12045

HYP:	A0257_02275

HYZ:	AXW84_14140

HNV:	DDQ68_08665

HYH:	D3Y59_01775

HYJ:	FHG12_15140

HQI:	H9L05_13510

HRS:	HER32_04360

HBN:	GUY19_00085

HTS:	HMJ29_00255

HMT:	MTP16_21190

HTB:	MTX78_15655

HYK:	O9Z63_10545

HSK:	H4317_07120

HCW:	O3303_08725

HSB:	MWH26_11625

HAEI:

MUN82_03465

HVL:	MUN86_15455

HCF:	MUN80_22265

RUF:	TH63_06180

RUD:	TH61_14005

NIB:	GU926_01490

MTT:	Ftrac_3481

RMR:

Rmar_0037

RMG:	Rhom172_0037

RBAR:

AWN76_012925

SRU:

SRU_2238

SRM:

SRM_02466

» show all

Reference

1 [PMID:23463507]

Authors

Patil AG, Sang PB, Govindan A, Varshney U

Title

Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance.

Journal

J Biol Chem 288:11252-62 (2013)
DOI:10.1074/jbc.M112.442566

Sequence

[mtu:Rv2985]

Other DBs

ExplorEnz - The Enzyme Database:

3.6.1.69

IUBMB Enzyme Nomenclature:

3.6.1.69

ExPASy - ENZYME nomenclature database:

3.6.1.69

BRENDA, the Enzyme Database:

3.6.1.69

DBGET integrated database retrieval system