Entry
Name
prenyl-diphosphate phosphatase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
prenyl diphosphate/3-methylbut-3-en-1-yl diphosphate phosphohydrolase
Reaction(IUBMB)
(1) prenyl diphosphate + H2O = prenyl phosphate + phosphate [RN:
R12896 ];
(2) 3-methylbut-3-en-1-yl diphosphate + H2O = 3-methylbut-3-en-1-yl phosphate + phosphate [RN:
R13127 ]
Reaction(KEGG)
Substrate
prenyl diphosphate [CPD:
C00235 ];
H2O [CPD:
C00001 ];
3-methylbut-3-en-1-yl diphosphate [CPD:
C00129 ]
Product
prenyl phosphate [CPD:
C21214 ];
phosphate [CPD:
C00009 ];
3-methylbut-3-en-1-yl phosphate [CPD:
C20345 ]
Comment
The enzyme, characterized from the methanogenic archaeon Methanosarcina mazei, belongs to the Nudix hydrolase family (a superfamily of hydrolytic enzymes capable of cleaving nucleoside diphosphates linked to a moiety). Its main purpose is to provide the substrate for EC
2.5.1.129 , flavin prenyltransferase.
History
EC 3.6.1.76 created 2022
Pathway
Orthology
K25520 prenyl-diphosphate phosphatase
Genes
» show all
Taxonomy
Reference
Authors
Ishibashi Y, Matsushima N, Ito T, Hemmi H.
Title
Isopentenyl diphosphate/dimethylallyl diphosphate-specific Nudix hydrolase from the methanogenic archaeon Methanosarcina mazei.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.76
ExPASy - ENZYME nomenclature database: 3.6.1.76