Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including 'nerve gases'). Inhibited by chelating agents; requires divalent cations. Related to EC 3.1.8.1 aryldialkylphosphatase.
History
EC 3.8.2.2 created 1961 as EC 3.8.2.1, transferred 1992 to EC 3.1.8.2, reinstated 2023 as EC 3.8.2.1
Reference
1
Authors
Augustinsson, K.-B. and Heimburger, G.
Title
Enzymatic hydrolysis of organophosphorus compounds. I. Occurrence of enzymes hydrolysing dimethyl-amido-ethoxy-phosphoryl cyanide (Tabun).
Journal
Acta Chem Scand 8:753-761 (1954)
Reference
2
Authors
Augustinsson, K.-B. and Heimburger, G.
Title
Enzymatic hydrolysis of organophosphorus compounds. II. Analysis of reaction products in experiments with Tabun and some properties of blood plasma tabunase.
Journal
Acta Chem Scand 8:762-767 (1954)
Reference
3
Authors
Augustinsson, K.-B. and Heimburger, G.
Title
Enzymatic hydrolysis of organophosphorus compounds. IV. Specificity studies.