KEGG ENZYME: 3.9.1.3

ENZYME: 3.9.1.3

Entry

EC 3.9.1.3                  Enzyme

Name

phosphohistidine phosphatase;
PHPT1 (gene name);
protein histidine phosphatase;
PHP

Class

Hydrolases;
Acting on phosphorus-nitrogen bonds;
Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date)

Sysname

[protein]-N-phospho-L-histidine phosphohydrolase

Reaction(IUBMB)

a [protein]-N-phospho-L-histidine + H2O = a [protein]-L-histidine + phosphate [RN:R11258 R11259]

Reaction(KEGG)

R11258 R11259

Substrate

[protein]-N-pros-phospho-L-histidine [CPD:C04261];
[protein]-N-tele-phospho-L-histidine [CPD:C04262];
H2O [CPD:C00001]

Product

[protein]-L-histidine [CPD:C00615];
phosphate [CPD:C00009]

Comment

This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- and tele-nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most) [4]. The substrate specificity depends on the amino acid sequence or structural context of the phosphohistidine in a phosphoprotein. The enzyme is also active on free phosphoramidate [1,4] and peptide-bound phospholysine [5].

History

EC 3.9.1.3 created 2016

Orthology

K01112

phosphohistidine phosphatase

Genes

HSA:	29085(PHPT1)

PTR:	104008061(PHPT1)

PPS:	100981762(PHPT1)

GGO:	101127423(PHPT1)

PON:	100174576(PHPT1)

NLE:	100605190(PHPT1)

HMH:	116475888(PHPT1)

MCC:	721674(PHPT1)

MCF:	123566769(PHPT1)

MTHB:

126937104

MNI:

105471951

CSAB:

103239603(PHPT1)

CATY:

105580662(PHPT1) 105600972

PANU:

101017324

TGE:	112608090(PHPT1)

MLEU:

105543263(PHPT1)

RRO:	104659598 104669652(PHPT1)

RBB:	108542886(PHPT1)

TFN:	117099142(PHPT1)

PTEH:

111553032(PHPT1)

CANG:

105512467 105522702(PHPT1)

CJC:	100402534(PHPT1)

SBQ:	101036378(PHPT1)

CIMI:

108287279(PHPT1)

CSYR:

103255588(PHPT1)

MMUR:

105882291(PHPT1)

LCAT:

123645607(PHPT1)

PCOQ:

105818708(PHPT1)

OGA:	100967212(PHPT1)

MMU:	75454(Phpt1)

MCAL:

110289834(Phpt1)

MPAH:

110319198(Phpt1)

RNO:	296571(Phpt1)

MCOC:

116089832(Phpt1)

ANU:	117711256(Phpt1)

MUN:	110557001(Phpt1)

CGE:	100761523(Phpt1)

MAUA:

101822790(Phpt1)

PROB:

127222606(Phpt1)

PLEU:

114692801(Phpt1)

MORG:

121446561 121462478(Phpt1)

AAMP:

119818735(Phpt1) 119827474

NGI:	103741191(Phpt1)

HGL:	101705528(Phpt1)

CPOC:

100733710(Phpt1)

CCAN:

109699335(Phpt1)

DORD:

105984561(Phpt1)

DSP:	122099713(Phpt1)

PLOP:

125351487(Phpt1)

NCAR:

124964485

MMMA:

107159238(Phpt1)

OPI:	101528342(PHPT1)

TUP:	102485128(PHPT1)

GVR:	103583004 103610050(PHPT1)

CFA:	491245(PHPT1)

CLUD:

112677463(PHPT1)

VVP:	112906872(PHPT1)

VLG:	121472787(PHPT1)

NPO:	129517978(PHPT1)

AML:	100475360(PHPT1)

UMR:	103675296(PHPT1)

UAH:	113248562 113248616

UAR:	123796339(PHPT1)

ELK:

111146033

LLV:

125083823

MPUF:

101681624(PHPT1)

MNP:	132024230(PHPT1)

MLK:	131812690(PHPT1)

NVS:	122916817(PHPT1)

ORO:	101371338(PHPT1)

EJU:	114201741(PHPT1)

ZCA:	113934639(PHPT1)

MLX:	118018178(PHPT1)

NSU:	110581251(PHPT1)

LWW:	102735640(PHPT1)

FCA:	101098343(PHPT1)

PYU:	121020250(PHPT1)

PBG:	122474332(PHPT1)

PVIV:

125150906(PHPT1)

LRUF:

124522425

PTG:	102966231(PHPT1)

PPAD:

109258803(PHPT1)

PUC:

125923484

HHV:	120226446(PHPT1)

BTA:	618691(PHPT1)

BOM:	102281185(PHPT1)

BIU:	109566628(PHPT1)

BBUB:

112582691(PHPT1)

BBIS:

104998549(PHPT1)

CHX:	102185373(PHPT1)

OAS:	101109947(PHPT1)

BTAX:

128056315(PHPT1)

ODA:	120852207(PHPT1)

CCAD:

122442429(PHPT1)

MBEZ:

129539025(PHPT1)

CFR:	102511170(PHPT1)

CBAI:

105068591(PHPT1)

CDK:	105106201(PHPT1)

VPC:	102538318(PHPT1)

BACU:

103014630(PHPT1)

BMUS:

118896970(PHPT1)

LVE:	103089622(PHPT1)

OOR:	101282046(PHPT1)

DLE:	111177012(PHPT1)

PCAD:

102979869(PHPT1)

PSIU:

116755607(PHPT1)

NASI:

112411452(PHPT1)

EPZ:	103567827(PHPT1)

EAI:	106845536(PHPT1)

MYB:	106724000(PHPT1)

MYD:	102771209(PHPT1)

MMYO:

118655322(PHPT1)

PKL:	118707069(PHPT1)

EFUS:

103295967(PHPT1)

MNA:	107536210(PHPT1)

DRO:	112306585(PHPT1)

SHON:

118980380(PHPT1)

AJM:	119036153(PHPT1)

PDIC:

114504347(PHPT1)

PHAS:

123823503(PHPT1)

MMF:	118629879(PHPT1)

PPAM:

129079531(PHPT1)

HAI:	109381651(PHPT1)

RFQ:	117032053(PHPT1)

PALE:

102888846(PHPT1)

PGIG:

120599796(PHPT1)

PVP:

105298615

RAY:	107503115(PHPT1)

MJV:	108406830(PHPT1)

TOD:	119230970(PHPT1)

SARA:

101539699(PHPT1)

SETR:

126009316(PHPT1)

LAV:	100670682(PHPT1)

TMU:

101354410

ETF:	101652033(PHPT1)

MDO:	100017116(PHPT1)

GAS:	123235161(PHPT1)

SHR:	100934482(PHPT1)

AFZ:

127549128

PCW:	110205314(PHPT1)

OAA:	100085648(PHPT1) 114808686

GGA:	424401 770750(PHPT1)

PCOC:

116230481 116234441(PHPT1)

MGP:	100546004(PHPT1) 100548654

CJO:	107317233 107321627(PHPT1)

TPAI:

128072427 128079801(PHPT1)

LMUT:

125693539 125702620(PHPT1)

NMEL:

110402443 110406762(PHPT1)

APLA:

101795226 106015461(PHPT1)

ACYG:

106041604

CATA:

118243680 118257050(PHPT1)

AFUL:

116491937 116497040(PHPT1)

TGU:	100189978 100190052(PHPT1)

LSR:	110472220(PHPT1) 110478906

SCAN:

103823377 115484621(PHPT1)

PMOA:

120507369(PHPT1) 120512220

OTC:	121336916(PHPT1) 121344270

PRUF:

121357656(PHPT1) 121359785

FAB:	101807901(PHPT1) 101808988

OMA:	130256489 130260190(PHPT1)

PHI:	102106999(PHPT1) 102114133

PMAJ:

107208231 107212113(PHPT1)

CCAE:

111932649(PHPT1)

CCW:	104695463 120410902(PHPT1)

CBRC:

103612709(PHPT1)

ETL:	114063561 114064156(PHPT1)

ZAB:	102066033(PHPT1) 102075313

ACHL:

103804123(PHPT1)

SVG:	106852304 106856022(PHPT1)

MMEA:

130583562 130584586(PHPT1)

HRT:	120756677 120761790(PHPT1)

CLV:	102094516(PHPT1) 102095723

EGZ:	104135669(PHPT1)

NNI:

104010433

PCRI:

104026185 104035203

PLET:

104623371

EHS:	104504822(PHPT1)

PCAO:

104040487(PHPT1)

TALA:

104355632 122152753(PHPT1)

PADL:

103914107(PHPT1)

AFOR:

103894010(PHPT1)

ACHC:

115335467(PHPT1) 115348775

HALD:

104310519 104320326

HLE:	104830012(PHPT1) 104840576

AGEN:

126042351 126052121

GCL:

127018923

CCRI:

104156588(PHPT1)

CMAC:

104474968(PHPT1)

MUI:	104535893 104547957

BREG:

104632446(PHPT1)

FGA:

104069495

GSTE:

104250601 104251096

LDI:

104341936

MNB:	103778769(PHPT1)

OHA:

104333748

NNT:	104399348(PHPT1)

SHAB:

115611945 116915283(PHPT1)

DPUB:

104301607(PHPT1)

PGUU:

104457897 104469530

ACAR:

104517855(PHPT1)

CPEA:

104389000

AVIT:

104269813

CVF:	104293408(PHPT1)

RTD:	128914285 128917471(PHPT1)

CUCA:

104058374(PHPT1)

TEO:	104369861 104373787

AAM:	106493878 106494224(PHPT1)

AROW:

112969757(PHPT1) 112975101

NPD:	112951190 112956106(PHPT1)

TGT:	104574633(PHPT1)

DNE:	112986797(PHPT1) 112997426

SCAM:

104139805(PHPT1)

ASN:	102369468(PHPT1) 102376846

AMJ:	102563666(PHPT1) 102574934

CPOO:

109306952 109313786(PHPT1)

GGN:	109287010 109292721 109292827

PSS:	102447649 102448039(PHPT1)

CMY:	102944694(PHPT1) 119566950

CCAY:

125623461(PHPT1) 125640749

DCC:	119844291(PHPT1) 119860108

CPIC:

103305695(PHPT1)

TST:	117867216(PHPT1) 117882209

CABI:

116819230(PHPT1) 116839894

MRV:	120370658 120386561(PHPT1)

ACS:	100557188 100558315(phpt1)

ASAO:

132763629(PHPT1) 132772748

PVT:	110087442(PHPT1) 110090928

SUND:

121936591(PHPT1)

PBI:	103056567(PHPT1)

PMUR:

107302546(PHPT1) 107302839

CTIG:

120299319 120308624(PHPT1)

TSR:	106541992(PHPT1) 106543739

PGUT:

117661233 117676635(PHPT1)

APRI:

131196037

PTEX:

113438162 113443791(PHPT1)

NSS:	113421677(PHPT1)

VKO:	123028349(PHPT1)

PMUA:

114590103 114598606

PRAF:

128406344(PHPT1) 128415316

ZVI:	118084554(PHPT1) 118089152

HCG:	128325311 128338981(PHPT1)

GJA:	107106118 107115168(PHPT1)

STOW:

125433150 125442288(PHPT1)

EMC:	129326558 129329675 129342332(PHPT1)

XLA:	108714493 734838(phpt1.L)

XTR:	100494164 100497662(phpt1)

NPR:	108787256(PHPT1) 108797455

RTEM:

120914044(PHPT1) 120925483

BBUF:

120977682(PHPT1)

BGAR:

122946508(PHPT1)

MUO:	115472295 115472664(PHPT1)

GSH:	117346898 117358239 117359909 117367586(PHPT1) 117368386

DRE:	445172(phpt1) 558617

SRX:	107726439 107732399 107736930 107739750

SANH:

107661392 107692288 107696171 107698337

SGH:	107548800 107555634 107595677

CCAR:

109046032 109055981 109059078

CAUA:

113038789 113062817 113064113

CGIB:

127938883(si:dkey-51e6.1) 127942061 127986153

PTET:

122324277(si:dkey-51e6.1) 122326671(phpt1)

LROH:

127152962(phpt1) 127183412(si:dkey-51e6.1)

OMC:	131527591(si:dkey-51e6.1) 131529223(phpt1) 131535740

PPRM:

120490824(phpt1) 120493695(si:dkey-51e6.1)

RKG:	130078695(phpt1) 130103045(si:dkey-51e6.1)

MAMB:

125252538(phpt1) 125278195(si:dkey-51e6.1)

CIDE:

127504004

MASI:

127428733 127430614 127456670(si:dkey-51e6.1)

TROS:

130566323(si:dkey-51e6.1) 130569767(phpt1)

TDW:	130408391(phpt1) 130434101(si:dkey-51e6.1)

MANU:

129423653(phpt1) 129430166(si:dkey-51e6.1)

IPU:	100528926(phpt1) 108257519(si:dkey-51e6.1)

IFU:	128601472(si:dkey-51e6.1) 128622410(phpt1)

PHYP:

113535614(phpt1) 113546801

SMEO:

124376559(si:dkey-51e6.1) 124397986(phpt1)

TFD:	113647506(si:dkey-51e6.1) 113661745(phpt1)

TVC:	132842390 132859795(phpt1)

AMEX:

103037051 103043613(phpt1)

CMAO:

118815274(si:dkey-51e6.1) 118819680(phpt1)

EEE:	113573420(phpt1) 113585141

CHAR:

105902502(phpt1) 105907105(si:dkey-51e6.1)

TRU:	101073866(phpt1) 101075763

TFS:	130516796(phpt1) 130528737(si:dkey-51e6.1)

TNG:	GSTEN00008882G001 GSTEN00009029G001

LCO:	104918463 104936327

NCC:	104952282 104966792(phpt1)

TBEN:

117478724(phpt1) 117495229(si:dkey-51e6.1)

CGOB:

115017122(phpt1)

PGEO:

117445692(si:dkey-51e6.1) 117456167(phpt1)

GACU:

117539950(phpt1) 117550956(si:dkey-51e6.1)

EMAC:

134868807(phpt1) 134869796

ELY:	117254271(si:dkey-51e6.1) 117269410(phpt1)

EFO:	125896417(si:dkey-51e6.1) 125906258(phpt1)

PLEP:

121941185 121941186(si:dkey-51e6.1) 121960034(phpt1)

SLUC:

116034753(phpt1) 116063316(si:dkey-51e6.1)

ECRA:

117950545(si:dkey-51e6.1) 117959112(phpt1)

ESP:	116695705 116704255

PFLV:

114562027 114571134

GAT:	120824218(si:dkey-51e6.1) 120831892(phpt1)

PPUG:

119216305(si:dkey-51e6.1) 119226765(phpt1)

AFB:	129094847(si:dkey-51e6.1) 129102475(phpt1)

CLUM:

117730183(si:dkey-51e6.1) 117740392(phpt1)

PSWI:

130205311(phpt1)

MSAM:

119900793(si:dkey-51e6.1) 119914346(phpt1)

SCHU:

122865329(phpt1) 122877364(si:dkey-51e6.1)

CUD:	121512553(si:dkey-51e6.1) 121524772(phpt1)

ALAT:

119028554(si:dkey-51e6.1) 119030605(phpt1)

MZE:	101469098 101477977

ONL:	100707253 100711007

OAU:	116317335(si:dkey-51e6.1) 116319632(phpt1)

OLA:	101156809 101164173(phpt1)

OML:	112136128(phpt1) 112150210(si:dkey-51e6.1)

CSAI:

133454755(phpt1) 133457786

XMA:	102219858(phpt1) 102237406

XCO:	114149088(phpt1) 114150312

XHE:	116724600(phpt1) 116725848

PRET:

103463570(phpt1)

PFOR:

103132371 103142589 103154384

PLAI:

106937142(phpt1) 106963537

PMEI:

106905910(phpt1) 106916799

GAF:	122819188(phpt1) 122838805(si:dkey-51e6.1)

PPRL:

129366546(phpt1) 129374478(si:dkey-51e6.1)

CVG:	107098573 107105104(phpt1)

CTUL:

119772058(phpt1) 119797475(si:dkey-51e6.1)

GMU:	124872018(phpt1) 124874182(si:dkey-51e6.1)

NFU:	107375130(phpt1) 107393216

KMR:	108230593(si:dkey-51e6.1) 108241411(phpt1)

ALIM:

106513910 106536853

NWH:	119407869(si:dkey-51e6.1) 119424327(phpt1)

AOCE:

111571557(phpt1) 111573592

MCEP:

124996602(phpt1) 125009030(si:dkey-51e6.1)

CSEM:

103389195(phpt1) 103397941

POV:	109625906 109640317(phpt1)

SSEN:

122780480(si:dkey-51e6.1) 122787098(phpt1)

HHIP:

117760014(si:dkey-51e6.1) 117771825(phpt1)

HSP:	118125670(phpt1) 124854814(si:dkey-51e6.1)

SMAU:

118284840(phpt1) 118317702(si:dkey-51e6.1)

LCF:	108877419(si:dkey-51e6.1) 108894430(phpt1)

SDU:	111232112 111238479(phpt1)

SLAL:

111650119 111656307

XGL:	120790299(si:dkey-51e6.1) 120806635(phpt1)

HCQ:	109521666(phpt1) 109521667 109531910 109531911

SSCV:

125971576(si:dkey-51e6.1) 125979727

SBIA:

133491189(phpt1) 133503552

PEE:	133406160 133413798(phpt1)

PTAO:

133465139(phpt1) 133481336

BPEC:

110164001(phpt1) 110167832

MALB:

109964015 109970886(phpt1)

BSPL:

114854676(si:dkey-51e6.1) 114867375(phpt1)

SJO:	128361730(si:dkey-51e6.1) 128380323(phpt1)

SASA:

106560654(PHP14) 106563239(phpt1) 106565536(PHP14) 106591792

STRU:

115159513 115204128

OTW:	112219353 112231040(phpt1)

OMY:	100305331(si:dkey-51e6.1) 110509850(phpt1) 110523636

OGO:	123996557(si:dkey-51e6.1) 124006731(phpt1) 124048907

ONE:	115101215 115123406 115124338

OKI:	109868509 109874205 109883444

OKE:	118362319(si:dkey-51e6.1) 118385257 118387575

SALP:

111961565 111964070 112073273

SNH:	120021612(phpt1) 120025825 120055091(si:dkey-51e6.1)

CCLU:

121532864(si:dkey-51e6.1) 121541178(phpt1) 121583310

ELS:	105010032 105015090

SFM:	108935341 108938490(phpt1)

PKI:	111833403(phpt1) 111840127

AANG:

118207062 118213453 118224629(si:dkey-51e6.1)

LOC:	102685255 102688823(phpt1)

PSPA:

121310830(phpt1) 121330513(si:dkey-51e6.1)

ARUT:

117396799 117413291(si:dkey-51e6.1) 117417221 117962302

PSEX:

120515051(si:dkey-51e6.1) 120542165(phpt1)

LCM:	102349364 102354005(PHPT1)

CMK:	103183013(phpt1)

CPLA:

122547583 122554492(si:dkey-51e6.1)

HOC:	132819026(si:dkey-51e6.1) 132826009

LERI:

129701158(si:dkey-51e6.1) 129711805(phpt1)

PMRN:

116954435(PHPT1)

LRJ:	133357525 133357526

BFO:

118421611

BBEL:

109484605

SCLV:

120339634

SPU:

578308

LPIC:

129277608

APLC:

110976262

AJC:

117118906

SKO:

100366766

DME:	Dmel_CG18662(CG18662) Dmel_CG7929(ocn) Dmel_CG7931(janB) Dmel_CG7933(janA)

DER:	6541755 6554365 6554366 6554367

DSE:	6612802 6612803 6612804

DSI:	Dsimw501_GD17399(Dsim_janA) Dsimw501_GD17410(Dsim_janB) Dsimw501_GD17421(Dsim_ocn) Dsimw501_GD23579(Dsim_GD23579)

DYA:	Dyak_GE18815 Dyak_GE23419(Dyak_janA) Dyak_GE23420(Dyak_janB) Dyak_GE23422(Dyak_ocn)

DSR:	110181444 110186735 110186737 110186738

DPO:	4800255 4800256 4816257

DPE:	6593512 6594971 6594972

DMN:	108156373 108156374 108164053

DWI:	6642852 6651130 6651131

DGR:	6563047 6563048 6570080

DMO:	Dmoj_GI17452 Dmoj_GI23391 Dmoj_GI25917

DAZ:	108610590 108610598 108611997

DNV:	108649178 108649179 115564326

DHE:	111593762 111594466

CCAT:

101449770

BOD:

106622518

BDR:

105232070

RZE:	108357047 108358301

AOQ:

129248361

TDA:

119682140

MDE:

101895156

SCAC:

106086861

LCQ:

111675306

LSQ:

119609203

GFS:	119638083 119638116 119638139

ECOE:

129942586

CLON:

129613051

HIS:

119659619

AGA:

1281036

ACOZ:

120950552

AARA:

120896080

AMER:

121588007

ASTE:

118505705 118505722

AFUN:

125765186

AMOU:

128298886

AALI:

118461074

AAG:

5564632

AALB:

109411595 109421352

CQU:	CpipJ_CPIJ008917

CPII:

120419256

CNS:

116342337

BCOO:

119073423

AME:

100576467

ACER:

107995715 107997018

ALAB:

122716448

ADR:

102676473

AFLR:

105736956

BIM:	100744904 112211996

BBIF:

117206009

BVK:

117238069

BVAN:

117154092

BTER:

100651751

BAFF:

126916651

BPYO:

122565863

BPAS:

132904977

FVI:	122529587 122538095

CCAL:

108628614

OBB:

114873203

OLG:

117605249

MGEN:

117217963

NMEA:

116428856

CGIG:

122398408

SOC:

105201982

MPHA:

105834099

AEC:

105149025

PBAR:

105427733

VEM:

105565463

HST:

105191607

DQU:

106745497

CFO:

105254982

FEX:

115233218

LHU:

105667425

PGC:

109856667

OBO:

105283372

PCF:

106786194

VPS:

122633228

VCRB:

124429683

VVE:

124953978

NVI:

103316255

CSOL:

105369036

TPRE:

106650211

LHT:

122503404

LBD:

127276748

MDL:

103571115

CGLO:

123272555

FAS:

105266145

DAM:

107048261

AGIF:

122849149 122857560

CINS:

118074003

VCAN:

122410765

CCIN:

107272672 107273871

DSM:

124408235

NPT:

124216877

NFB:

124180288

NLO:

107225043

NVG:

124302814

AROA:

105693325

TCA:

662760

DPA:

109546278

AGRG:

126733991

ATD:

109593853

CSET:

123315555

AGB:

111692238

LDC:

111516748

NVL:

108558730

APLN:

108733430

PPYR:

116164355

OTU:

111413335

BMOR:

692960

BMAN:

114244039

MSEX:

115446598

DPL:	KGM_202223

BANY:

112050969

MJU:

123876956

NIQ:

126768446

VCD:

124530199

MCIX:

123665250

PMAC:

106707537 106710480

PPOT:

106111789

PXU:

106124081

PRAP:

110994993

PBX:

123714662

PNAP:

125059745

ZCE:

119829515

CCRC:

123696848

LSIN:

126976286

AAGE:

121730242

HAW:

110380765

HZE:

124630664

TNL:

113496671

SLIU:

111353553

OFU:

114353236

PXY:	105382204 105386807 105391318

PGW:

126374100

CFEL:

113373020 113386387

CCRN:

123299841

API:

100169489

DNX:

107173585

AGS:

114125221

RMD:

113557509

ACOO:

126838743

DVT:

126894265

BTAB:

109030869

CLEC:

106661103

HHAL:

106687771 106689582 112211694

NLU:

111057487

HVI:

124372446

MQU:

128991803

PHU:	Phum_PHUM448250

FOC:

113218271

TPAL:

117649042 117649947

ZNE:

110836614

CSEC:

111864719

SGRE:

126292023

FCD:

110861341

DPX:	DAPPUDRAFT_299626

DPZ:

124343356

PVM:

113821321

PJA:

122248936

PCHN:

125035265

HAME:

121873585

PCLA:

123756873

CQD:

128687272

PTRU:

123503191

ESN:

127006239

MNZ:

135207982

HAZT:

108670442

EAF:	111704055 111707739

TCF:

131879001

PPOI:

119101551

DSV:	119442547 119442548

RSAN:

119387420 119387421

VDE:	111247470 111254713

VJA:	111264455 111272614

TUT:

107359989

DPTE:

113788759

DFR:

124494664

CSCU:

111633646

PTEP:

107440439

ABRU:

129973080

SDM:

118196355

LPOL:

106468438 106475119

PMEO:

129592369 129592370

CEL:	CELE_F36A2.8(phip-1)

CBR:

CBG_12374

CRQ:	GCK72_002521

NAI:	NECAME_01690

BMY:	BM_BM17737(Bma-phip-1.1) BM_BM3860(Bma-phip-1.2)

LOA:	LOAG_00658 LOAG_00659

HRO:	HELRODRAFT_108413

LGI:	LOTGIDRAFT_150831

PCAN:

112564206 112575518

BGT:

106059796

GAE:	121384252 121388455 121392454

HRF:

124111368

HRJ:

124284336

CRG:

105328285

CVN:	111127240 111127241

CANU:

128155741

OED:

125680249

MYI:

110464427

PMAX:

117322012

MCAF:

127728266

MMER:

123548169

RPHI:

132745764

DPOL:

127840054

OBI:

106875271

OSN:

115230258

LAK:

106157674

NVE:

5506033

EPA:

110250310

ATEN:

116300319

ADF:

107343753

AMIL:

114961179

PDAM:

113682272

SPIS:

111339461

DGT:	114525596 114525699 114525700 114541810

XEN:

124453756

HMG:

100213884

HSY:

130613353

TAD:	TRIADDRAFT_53076

AQU:

100636166

SMO:	SELMODRAFT_107276

VCN:	VOLCADRAFT_37182

OLU:	OSTLU_30366

OTA:	OT_ostta03g00460

BPG:	Bathy14g00560

MIS:	MICPUN_60697

MPP:	MICPUCDRAFT_38336(JGI:MicpuC2_38336)

MBR:	MONBRDRAFT_22478

SRE:	PTSG_10862

DDI:	DDB_G0277367

DPP:	DICPUDRAFT_87363

BMIC:

BMR1_03g00735

TET:	TTHERM_01193520

PTM:	GSPATT00007713001 GSPATT00021487001

SMIN:

v1.2.015552.t1(symbB.v1.2.015552.t1) v1.2.024049.t1(symbB.v1.2.024049.t1)

PTI:	PHATRDRAFT_31870

FCY:	FRACYDRAFT_180190

AAF:	AURANDRAFT_21146

GTT:	GUITHDRAFT_104780

PFER:

IRI77_03835

» show all

Reference

1 [PMID:12383260]

Authors

Ek P, Pettersson G, Ek B, Gong F, Li JP, Zetterqvist O

Title

Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase.

Journal

Eur J Biochem 269:5016-23 (2002)
DOI:10.1046/j.1432-1033.2002.03206.x

Sequence

[hsa:29085]

Reference

2 [PMID:12468887]

Authors

Klumpp S, Hermesmeier J, Selke D, Baumeister R, Kellner R, Krieglstein J

Title

Protein histidine phosphatase: a novel enzyme with potency for neuronal signaling.

Journal

J Cereb Blood Flow Metab 22:1420-4 (2002)
DOI:10.1097/01.wcb.0000045041.03034.99

Reference

3 [PMID:17200567]

Authors

Baumer N, Maurer A, Krieglstein J, Klumpp S

Title

Expression of protein histidine phosphatase in Escherichia coli, purification, and determination of enzyme activity.

Journal

Methods Mol Biol 365:247-60 (2007)
DOI:10.1385/1-59745-267-X:247

Reference

4 [PMID:19836471]

Authors

Attwood PV, Ludwig K, Bergander K, Besant PG, Adina-Zada A, Krieglstein J, Klumpp S

Title

Chemical phosphorylation of histidine-containing peptides based on the sequence of histone H4 and their dephosphorylation by protein histidine phosphatase.

Journal

Biochim Biophys Acta 1804:199-205 (2010)
DOI:10.1016/j.bbapap.2009.10.007

Reference

5 [PMID:25574816]

Authors

Ek P, Ek B, Zetterqvist O

Title

Phosphohistidine phosphatase 1 (PHPT1) also dephosphorylates phospholysine of chemically phosphorylated histone H1 and polylysine.

Journal

Ups J Med Sci 120:20-7 (2015)
DOI:10.3109/03009734.2014.996720

Sequence

[hsa:29085]