KEGG   ENZYME: 4.1.1.118
Entry
EC 4.1.1.118                Enzyme                                 
Name
isophthalyl-CoA decarboxylase;
IPCD
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
isophthalyl-CoA carboxy-lyase
Reaction(IUBMB)
isophthalyl-CoA = benzoyl-CoA + CO2 [RN:R12486]
Reaction(KEGG)
R12486
Substrate
isophthalyl-CoA [CPD:C22204]
Product
benzoyl-CoA [CPD:C00512];
CO2 [CPD:C00011]
Comment
The enzyme, characterized from the bacterium Syntrophorhabdus aromaticivorans, participates in an anaerobic isophthalate degradation pathway. The enzyme requires a prenylated flavin mononucleotide cofactor.
History
EC 4.1.1.118 created 2019
Reference
1  [PMID:30647456]
  Authors
Junghare M, Spiteller D, Schink B
  Title
Anaerobic degradation of xenobiotic isophthalate by the fermenting bacterium Syntrophorhabdus aromaticivorans.
  Journal
ISME J 13:1252-1268 (2019)
DOI:10.1038/s41396-019-0348-5
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.118
IUBMB Enzyme Nomenclature: 4.1.1.118
ExPASy - ENZYME nomenclature database: 4.1.1.118
BRENDA, the Enzyme Database: 4.1.1.118

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