Entry |
|
Name |
phenylalanine decarboxylase;
L-phenylalanine decarboxylase;
aromatic L-amino acid decarboxylase (ambiguous);
L-phenylalanine carboxy-lyase
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Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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Sysname |
L-phenylalanine carboxy-lyase (phenylethylamine-forming)
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Reaction(IUBMB) |
L-phenylalanine = phenylethylamine + CO2 [RN: R00699]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A pyridoxal-phosphate protein. Also acts on tyrosine and other aromatic amino acids.
|
History |
EC 4.1.1.53 created 1972
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Pathway |
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Orthology |
K22427 | phenylalanine decarboxylase |
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Genes |
SLY: | 101248029 101248320 101248599 101249664 101263045 101264847 101265155 101265461 101265757 101268488 544085(hdc) 778254(AADC1A) 778255(AADC1B) 778256(AADC2) |
SPEN: | 107026800 107026802 107027073 107027079 107027080 107027236 107027252 107027311 107027331 107027771 107027995 107028163 |
SOT: | 102579202 102579840 102580376 102581292 102581308 102581623 102581954 102582616 102591703 102591875 102592044 102594070 |
SSTN: | 125841513 125841932 125842126 125842127 125842196 125842197 125842198 125842565 125842956 125843006 125843167 125850891 125853081 |
SDUL: | 129888409 129889446 129889447 129890378 129890379 129890423 129890425 129890647 |
CANN: | 107845032 107848433 107854628 107879725 |
LBB: | 132609201 132609427 132609429 132638304 132638305 132638306 |
NTA: | 107760316(hdc) 107768931 107789682 107795329 107800126 107800924 107804556 107809914 107812155 |
NSY: | 104220279 104224399 104228428 104237302 |
NTO: | 104095303 104095606 104096073 104097046 104097306 104103394 104112462 104113710 108946339 |
NAU: | 109206779 109206798 109219573 109221082 109231394 109234461 109239718 |
» show all
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Reference |
|
Authors |
LOVENBERG W, WEISSBACH H, UDENFRIEND S. |
Title |
Aromatic L-amino acid decarboxylase. |
Journal |
J Biol Chem 237:89-93 (1962) |
Reference |
|
Authors |
Schulz AR, Oliner L. |
Title |
The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.53 |
ExPASy - ENZYME nomenclature database: | 4.1.1.53 |
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