KEGG ENZYME: 4.1.2.34

ENZYME: 4.1.2.34

Entry

EC 4.1.2.34                 Enzyme

Name

4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase;
2'-carboxybenzalpyruvate aldolase;
(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase;
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase

Class

Lyases;
Carbon-carbon lyases;
Aldehyde-lyases

Sysname

(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming)

Reaction(IUBMB)

(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate + pyruvate [RN:R07713]

Reaction(KEGG)

R07713;
(other) R03465

Substrate

(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [CPD:C16149];
H2O [CPD:C00001]

Product

2-formylbenzoate [CPD:C03057];
pyruvate [CPD:C00022]

Comment

Involved, with EC 1.13.11.38 (1-hydroxy-2-naphthoate 1,2-dioxygenase), in the metabolism of phenanthrene in bacteria.

History

EC 4.1.2.34 created 1989

Pathway

ec00624

Polycyclic aromatic hydrocarbon degradation

ec01120

Microbial metabolism in diverse environments

Orthology

K11949

4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase

Genes

HYI:	K2M58_04770

MMC:

Mmcs_1629

MKM:

Mkms_1655

MJL:

Mjls_1602

MYE:	AB431_15660

MVA:

Mvan_0469

MGI:	Mflv_0588 Mflv_0676

MSP:	Mspyr1_01480

MRH:	MycrhN_3149

MGAD:

MGAD_32260

MMON:

EWR22_08310

MPAE:

K0O64_27595

MCRO:

MI149_00635

ROZ:	CBI38_30580

APN:	Asphe3_22010

AACD:

LWP59_27075

ARHD:

VSH64_07420

PPEL:

H6H00_18660

SBAE:

DSM104329_02540(phdJ)

MEMJ:

MJ1HA_1412

» show all

Reference

1 [PMID:6833175]

Authors

Barnsley EA.

Title

Phthalate pathway of phenanthrene metabolism: formation of 2'-carboxybenzalpyruvate.

Journal

J Bacteriol 154:113-7 (1983)
DOI:10.1128/JB.154.1.113-117.1983

Other DBs

ExplorEnz - The Enzyme Database:

4.1.2.34

IUBMB Enzyme Nomenclature:

4.1.2.34

ExPASy - ENZYME nomenclature database:

4.1.2.34

UM-BBD (Biocatalysis/Biodegradation Database):

4.1.2.34

BRENDA, the Enzyme Database:

4.1.2.34

CAS:	86611-90-7

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