KEGG   ENZYME: 4.2.1.169
Entry
EC 4.2.1.169                Enzyme                                 
Name
3-vinyl bacteriochlorophyllide d 31-hydratase;
bchV (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
3-vinylbacteriochlorophyllide-d 31-hydro-lyase
Reaction(IUBMB)
a 3-(1-hydroxyethyl) bacteriochlorophyllide d = a 3-vinyl bacteriochlorophyllide d + H2O [RN:R11506]
Reaction(KEGG)
R11506 > R11510 R11511 R11512 R11513
Substrate
3-(1-hydroxyethyl) bacteriochlorophyllide d
Product
3-vinyl bacteriochlorophyllide d [CPD:C21426];
H2O [CPD:C00001]
Comment
This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green flimentous bacteria (Chloroflexaceae), is involved in the biosynthesis of bacteriochlorophylls c, d and e. It acts in the direction of hydration, and the hydroxyl group that is formed is essential for the ability of the resulting bacteriochlorophylls to self-aggregate in the chlorosomes, unique light-harvesting antenna structures found in these organisms. The product is formed preferentially in the (R)-configuration.
History
EC 4.2.1.169 created 2016
Pathway
ec00860  Porphyrin metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K13603  3-vinyl bacteriochlorophyllide hydratase
Genes
CTE: CT1776
CPC: Cpar_0430
CLZ: BIU88_02085 BIU88_11020
CCH: Cag_1644
CPH: Cpha266_0198 Cpha266_2005
CPB: Cphamn1_0268
CLI: Clim_1974
PVI: Cvib_0370
PLT: Plut_0408
PPH: Ppha_2338 Ppha_2749
PAA: Paes_1805
PROC: Ptc2401_00214 Ptc2401_01902
PRS: B9H02_09070
PROS: CHL67_01210(bchF)
PROW: OO006_13045(bchF)
PROI: OO005_12015(bchF)
CTS: Ctha_2718
 » show all
Reference
1  [PMID:16245042]
  Authors
Frigaard NU, Chew AG, Li H, Maresca JA, Bryant DA
  Title
Chlorobium tepidum: insights into the structure, physiology, and metabolism of a green sulfur bacterium derived from the complete genome sequence.
  Journal
Photosynth Res 78:93-117 (2003)
DOI:10.1023/B:PRES.0000004310.96189.b4
  Sequence
[cte:CT1776]
Reference
2  [PMID:26331578]
  Authors
Harada J, Teramura M, Mizoguchi T, Tsukatani Y, Yamamoto K, Tamiaki H
  Title
Stereochemical conversion of C3-vinyl group to 1-hydroxyethyl group in bacteriochlorophyll c by the hydratases BchF and BchV: adaptation of green sulfur bacteria to limited-light environments.
  Journal
Mol Microbiol 98:1184-98 (2015)
DOI:10.1111/mmi.13208
  Sequence
[cte:CT1776]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.169
IUBMB Enzyme Nomenclature: 4.2.1.169
ExPASy - ENZYME nomenclature database: 4.2.1.169
BRENDA, the Enzyme Database: 4.2.1.169

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (6)   
   KEGG REACTION (5)   
   KEGG RCLASS (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (21)   
All databases (43)   

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