KEGG   ENZYME: 4.2.2.26
Entry
EC 4.2.2.26                 Enzyme                                 
Name
oligo-alginate lyase;
aly (gene name) (ambiguous);
oalS17 (gene name);
oligoalginate lyase;
exo-oligoalginate lyase
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
Sysname
alginate oligosaccharide 4-deoxy-alpha-L-erythro-hex-4-enopyranuronate-(1->4)-hexananopyranuronate lyase
Reaction(IUBMB)
Cleavage of poly(4-deoxy-alpha-L-erythro-hexopyranuronoside) oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their non-reducing ends into 4-deoxy-alpha-L-erythro-hex-4-enopyranuronate monosaccharides.
Comment
The enzyme degrades unsaturated oligosaccharides produced by the action of alginate lyases (EC 4.2.2.3 and EC 4.2.2.11) on alginate, by repeatedly removing the unsaturated residue from the non-reducing end until only unsaturated monosaccharides are left. The enzyme catalyses a beta-elimination reaction, generating a new unsaturated non-reducing end after removal of the pre-existing one.
History
EC 4.2.2.26 created 2015
Orthology
K20525  oligo-alginate lyase
Genes
KGO: CEW81_15485
KLU: K7B04_14075
KCY: RIN60_14365
SFO: Z042_21520
RAH: Rahaq_2074
RACE: JHW33_06460
RAQ: Rahaq2_2212
RAA: Q7S_10515
RVC: J9880_19105
RIU: I2123_12390
EAME: GXP68_10025
XAR: XB05_00680
XHY: FZ025_04470
XEU: XSP_001205
XAG: HEP73_03146
XAS: HEP74_02963
SML: Smlt2602
SMT: Smal_2067
SRH: BAY15_0476
SLM: BIZ42_10915
STEM: CLM74_16325
STES: MG068_10895
SINC: DAIF1_32030
SPAQ: STNY_R22840
STEQ: ICJ04_13255
SGEN: RKE57_11200
PSUW: WQ53_03470
VAG: N646_4459 N646_4460
VHR: AL538_15535 AL538_15540
VOW: A9237_02440 A9237_02445
VSP: VS_1246 VS_1247
VEU: IXK98_14685 IXK98_14690
VBR: A6E01_15020 A6E01_15025
VAF: D1115_05485 D1115_05490
VNL: D3H41_17415 D3H41_17420
VCC: FAZ90_06435 FAZ90_06440
VAS: GT360_15085 GT360_15090
VSL: LTQ54_15605 LTQ54_15610
VPG: LZI70_17695 LZI70_17700
VCRA: IS519_00695 IS519_00700
VLE: ISX51_07850 ISX51_07855
VSY: K08M4_12390 K08M4_12400
AWD: AWOD_II_1150 AWOD_II_1151
PGB: H744_1c1644 H744_1c1645
AVN: Avin_46500
AVL: AvCA_46500
AVD: AvCA6_46500
ACX: Achr_5040
SFR: Sfri_3104
SJA: SJ2017_1079
SLJ: EGC82_17620
SMAI: EXU30_09955 EXU30_09960
SPOL: FH971_04070
SINV: K8B83_13145 K8B83_13150 K8B83_19175
COLW: A3Q33_13235
COLA: DBO93_13855 DBO93_13910
COV: EKO29_05460
CBER: B5D82_13235 B5D82_13295
THT: E2K93_04470
THAP: FNC98_00220
PHA: PSHAa1748(alyll)
PIA: PI2015_1887
PBW: D172_011660
PEA: PESP_a2549
PART: PARC_a2609
PAGA: PAGA_a1383
PCAR: PC2016_1119
PMAA: CPA52_10500
PDV: FFU37_09495
AMAC: MASE_04140
AMB: AMBAS45_04405
ALT: ambt_05125
AAL: EP13_15685
ASP: AOR13_1043
ASQ: AVL57_13410
AAW: AVL56_12520
ALE: AV939_12325
ALZ: AV940_12085
SALM: D0Y50_18865
GAG: Glaag_3645
PMES: FX988_03261
PAT: Patl_3651
CATE: C2869_02775
AGZ: M0C34_09010 M0C34_09015
AGQ: LQZ07_11285 LQZ07_11290
CATT: OLW01_17880
PMAW: MACH26_09680
CEB: B0D95_02120
SDE: Sde_3284(alg17A)
SAGA: M5M_10445
GIL: NHM04_04305
MTHD: A3224_00425
MAGA: Mag101_00420
MBRG: PVT68_15520
HALC: EY643_05725
MMAI: sS8_3472
GAI: IMCC3135_30035
HAF: C8233_00690 C8233_00695
CMAI: BFX80_07160 BFX80_07165
MARS: A8C75_02220 A8C75_02225
MRZ: KDW95_14115 KDW95_14120
CFH: C1707_09410
BSB: Bresu_2896
BDM: EQG53_08455
BND: KWG56_16500
MMR: Mmar10_0256
HBA: Hbal_2771
NRE: BES08_00050
NOV: TQ38_023940
SPHK: SKP52_04175
SPHP: LH20_00370
STER: AOA14_11265
SPHQ: BWQ93_09895
SPHX: E5675_06715
SPHU: SPPYR_0943
SKR: BRX40_02300
SPHC: CVN68_20060
SPAP: H3Z74_06340
SARI: H5J25_12810
SSUA: FPZ54_03250
SCAB: LZK98_13080
SDON: M9980_09000
SPHY: CHN51_02465
SPHL: LPB140_00300
PARP: HFP51_00430
PHAO: HF685_13560
AMX: AM2010_1736
PMAS: NCF86_09620
ADO: A6F68_01721
TFV: IDJ81_07185
CNA: AB433_04690
ERY: CP97_03810
ERF: FIU90_09070
TMK: QGN29_05695
GYM: GYMC10_3686
PSAB: PSAB_17950
PBJ: VN24_16145
POW: IJ21_37920
PDH: B9T62_12600
PVO: PVOR_18484
PLW: D5F53_11790
PCHI: PC41400_19575
ASOC: CB4_00526
CPY: Cphy_0489
CSH: Closa_0105
VPY: HZI73_21220
CSC: Csac_2721
SALA: ESZ53_09770
PSEY: GU243_13585
BCV: Bcav_3334 Bcav_3344
OBT: OPIT5_15555 OPIT5_17440 OPIT5_18925 OPIT5_27565
AAGG: ETAA8_58750
PND: Pla175_23860(hepC)
STQ: Spith_1748
SUS: Acid_4041
IPO: Ilyop_2136
GBA: J421_1193
BOA: Bovatus_00025 Bovatus_03848
BCEL: BcellWH2_03161 BcellWH2_04826
BIS: DXK01_006440 DXK01_008725
BUN: Bun01g_02180
BEG: INE88_01839
BFC: BacF7301_04405
BDO: EL88_16420
BDH: GV66_00670
PMUC: ING2E5A_0343
PSAC: PSM36_2063
TTZ: FHG85_04010
MBAS: ALGA_3305
NKO: Niako_5223
NSO: NIASO_03465 NIASO_04790
NIA: A8C56_19530
FGG: FSB75_07860
PSEG: D3H65_19220
PGO: FSB84_21275
PHE: Phep_0331
PEP: AQ505_11715
PCM: AY601_1649
PSTY: BFS30_00305
PEJ: FYC62_00980
PGJ: QG516_25180
PSN: Pedsa_1196
MMAB: HQ865_17725
EST: DN752_00830 DN752_22945
SPIK: EXU85_21470
SPIB: G8759_17385
ALS: DJ013_05545 DJ013_09505
RUP: DTQ70_08520
FPF: DCC35_17600
FLM: MY04_2549
FLL: EI427_11105
FYA: KMW28_03450
FKA: KM029_18335
CLIT: OQ292_34430
REK: N6H18_03930
RCG: N7E81_12945
PPSV: PEPS_32150 PEPS_32240
GFO: GFO_1151
FFA: FFWV33_03540
FKI: FK004_07155
FCR: HYN56_19355
FNK: E1750_01145
CAT: CA2559_11508
MARM: YQ22_05100
MART: BTR34_05385
MARE: EJ994_16720
CAO: Celal_4221
CLY: Celly_0295
CLH: IX49_01145
CBAL: M667_17460
CBAT: M666_17460
COMN: PBN93_01460
KDI: Krodi_0315
DOK: MED134_10670
DDO: I597_0903
DOD: DCS32_10570
LAN: Lacal_1748
LVN: BWR22_11825
ZGA: ZOBELLIA_2624(alyA3) ZOBELLIA_3452
NDO: DDD_0330(alyll)
NUL: R1T42_07200
POM: MED152_09820
POB: LPB03_09610
PRN: BW723_07355
POLA: BXQ17_10045
PHAL: H9I45_00595
PPEC: H9W90_14125
PUN: NQP51_08945
SZE: AW14_12520
AHZ: APS56_06060 APS56_15085
TJE: TJEJU_2494(alyA3)
WFU: AXE80_11225
FOP: FNB79_00985
OLL: CW732_00355
OAQ: DZC78_07845
FEK: C1H87_08185
TAJ: C1A40_05220
KAN: IMCC3317_38130
MARF: CJ739_3056
AQB: D1818_06345
AQA: D1815_01040
AQD: D1816_00480
PSYN: E9099_09530
PPON: MUN68_012555
MGEL: G5B37_00450
ASAG: FGM00_07275
FLG: LV716_03090
MAQI: LDL77_02525
FBE: FF125_19655
ALUT: O5O44_07265
LUY: QZH61_02195
EAO: BD94_3097
EMN: M876_12940
EEN: BBD30_10785
ELB: VO54_03461
EGO: BBD34_05300
EGM: AYC65_01410
ELZ: FCS00_15310
CSAL: NBC122_01621
CHRC: QGN23_13830
KFA: Q73A0000_08505
OHO: Oweho_2211
RMR: Rmar_1166
RLO: GQ464_011560
RBAR: AWN76_018385
MRO: MROS_1366
 » show all
Reference
1  [PMID:10913091]
  Authors
Hashimoto W, Miyake O, Momma K, Kawai S, Murata K
  Title
Molecular identification of oligoalginate lyase of Sphingomonas sp. strain A1 as  one of the enzymes required for complete depolymerization of alginate.
  Journal
J Bacteriol 182:4572-7 (2000)
DOI:10.1128/JB.182.16.4572-4577.2000
Reference
2  [PMID:22281843]
  Authors
Kim HT, Chung JH, Wang D, Lee J, Woo HC, Choi IG, Kim KH
  Title
Depolymerization of alginate into a monomeric sugar acid using Alg17C, an exo-oligoalginate lyase cloned from Saccharophagus degradans 2-40.
  Journal
Appl Microbiol Biotechnol 93:2233-9 (2012)
DOI:10.1007/s00253-012-3882-x
  Sequence
[sde:Sde_3284]
Reference
3  [PMID:24795372]
  Authors
Jagtap SS, Hehemann JH, Polz MF, Lee JK, Zhao H
  Title
Comparative biochemical characterization of three exolytic oligoalginate lyases from Vibrio splendidus reveals complementary substrate scope, temperature, and pH adaptations.
  Journal
Appl Environ Microbiol 80:4207-14 (2014)
DOI:10.1128/AEM.01285-14
Reference
4  [PMID:25335746]
  Authors
Wang L, Li S, Yu W, Gong Q
  Title
Cloning, overexpression and characterization of a new oligoalginate lyase from a  marine bacterium, Shewanella sp.
  Journal
Biotechnol Lett 37:665-71 (2015)
DOI:10.1007/s10529-014-1706-z
Other DBs
ExplorEnz - The Enzyme Database: 4.2.2.26
IUBMB Enzyme Nomenclature: 4.2.2.26
ExPASy - ENZYME nomenclature database: 4.2.2.26
BRENDA, the Enzyme Database: 4.2.2.26

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   KEGG ORTHOLOGY (1)   
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