KEGG   ENZYME: 4.2.3.109
Entry
EC 4.2.3.109                Enzyme                                 
Name
(-)-sabinene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-sabinene-forming]
Reaction(IUBMB)
geranyl diphosphate = (-)-sabinene + diphosphate [RN:R09965]
Reaction(KEGG)
R09965
Substrate
geranyl diphosphate [CPD:C00341]
Product
(-)-sabinene [CPD:C20242];
diphosphate [CPD:C00013]
Comment
Requires Mg2+. Isolated from Pinus contorta (lodgepole pine) as cyclase I [1] and from Conocephalum conicum (liverwort) [2].
History
EC 4.2.3.109 created 2012
Reference
1  [PMID:8307957]
  Authors
Savage TJ, Hatch MW, Croteau R
  Title
Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase.
  Journal
J Biol Chem 269:4012-20 (1994)
Reference
2  [PMID:12941302]
  Authors
Peters RJ, Croteau RB
  Title
Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases.
  Journal
Arch Biochem Biophys 417:203-11 (2003)
DOI:10.1016/S0003-9861(03)00347-3
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.109
IUBMB Enzyme Nomenclature: 4.2.3.109
ExPASy - ENZYME nomenclature database: 4.2.3.109
BRENDA, the Enzyme Database: 4.2.3.109

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (8)   
   InterPro (8)   
All databases (15)   

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