| Entry |
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| Name |
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(2E,6E,10E,14E)-geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, ophiobolin-F-forming)
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| Reaction(IUBMB) |
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O = ophiobolin F + diphosphate [RN: R10762]
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| Reaction(KEGG) |
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| Substrate |
(2E,6E,10E,14E)-geranylfarnesyl diphosphate [CPD: C04217];
H2O [CPD: C00001]
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| Product |
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| Comment |
Isolated from the fungus Aspergillus clavatus. The product is a sesterterpenoid (C25 terpenoid).
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| History |
EC 4.2.3.145 created 2014
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| Orthology |
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| Genes |
» show all
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| Reference |
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| Authors |
Chiba R, Minami A, Gomi K, Oikawa H |
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| Title |
Identification of ophiobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.145 |
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