| Entry |
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| Name |
(-)-spiroviolene synthase
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, (-)-spiroviolene-forming]
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| Reaction(IUBMB) |
geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate [RN: R11823]
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| Reaction(KEGG) |
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| Substrate |
geranylgeranyl diphosphate [CPD: C00353]
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| Product |
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| Comment |
The enzyme, which forms the diterpene (-)-spiroviolene, has been characterized from the bacterium Streptomyces violens.
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| History |
EC 4.2.3.158 created 2017
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| Reference |
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| Authors |
Rabe P, Rinkel J, Dolja E, Schmitz T, Nubbemeyer B, Luu TH, Dickschat JS |
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| Title |
Mechanistic Investigations of Two Bacterial Diterpene Cyclases: Spiroviolene Synthase and Tsukubadiene Synthase. |
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| Journal |
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| Reference |
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| Authors |
Xu H, Dickschat JS. |
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| Title |
Revision of the Cyclisation Mechanism for the Diterpene Spiroviolene and Investigations of Its Mass Spectrometric Fragmentation. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.158 |
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