Entry |
|
Name |
(-)-alpha-amorphene synthase
|
Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
|
Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-alpha-amorphene-forming]
|
Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = (-)-alpha-amorphene + diphosphate [RN: R11827]
|
Reaction(KEGG) |
|
Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
|
Product |
|
Comment |
The enzyme, found in the bacterium Streptomyces viridochromogenes, is specific for (2E,6E)-farnesyl diphosphate and produces only (-)-alpha-amorphene.
|
History |
EC 4.2.3.162 created 2017
|
Reference |
|
Authors |
Rabe P, Dickschat JS |
Title |
Rapid chemical characterization of bacterial terpene synthases. |
Journal |
|
Reference |
|
Authors |
Rinkel J, Rabe P, Garbeva P, Dickschat JS |
Title |
Lessons from 1,3-Hydride Shifts in Sesquiterpene Cyclizations. |
Journal |
|
Reference |
|
Authors |
Rabe P, Schmitz T, Dickschat JS |
Title |
Mechanistic investigations on six bacterial terpene cyclases. |
Journal |
|
Other DBs |
ExPASy - ENZYME nomenclature database: | 4.2.3.162 |
|