| Entry |
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| Name |
(+)-eremophilene synthase;
STC3 (gene name);
geoA (gene name)
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-eremophilene-forming]
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| Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = (+)-eremophilene + diphosphate [RN: R11829]
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| Reaction(KEGG) |
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| Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
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| Product |
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| Comment |
The enzyme has been identified in the myxobacterium Sorangium cellulosum and in the fungus Fusarium fujikuroi.
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| History |
EC 4.2.3.164 created 2017
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| Orthology |
| K22978 | (+)-eremophilene synthase |
| K22979 | (+)-eremophilene synthase |
|
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| Genes |
| FPOA: | FPOAC1_007502 FPOAC1_012967 FPOAC1_013813 |
| FVN: | FVRRES_10751 FVRRES_13838 |
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| Reference |
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| Authors |
Schifrin A, Ly TT, Gunnewich N, Zapp J, Thiel V, Schulz S, Hannemann F, Khatri Y, Bernhardt R |
|---|
| Title |
Characterization of the gene cluster CYP264B1-geoA from Sorangium cellulosum So ce56: biosynthesis of (+)-eremophilene and its hydroxylation. |
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| Journal |
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| Sequence |
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| Reference |
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|---|
| Authors |
Burkhardt I, Siemon T, Henrot M, Studt L, Rosler S, Tudzynski B, Christmann M, Dickschat JS |
|---|
| Title |
Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.164 |
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