Entry
Name
dolabella-3,7-dien-18-ol synthase;
TPS20 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranylgeranyl-diphosphate diphosphate-lyase [cyclizing, (3E,7E)-dolabella-3,7-dien-18-ol-forming]
Reaction(IUBMB)
geranylgeranyl diphosphate + H2O = (3E,7E)-dolabella-3,7-dien-18-ol + diphosphate [RN:
R11832 ]
Reaction(KEGG)
Substrate
Product
(3E,7E)-dolabella-3,7-dien-18-ol [CPD:
C21687 ];
diphosphate [CPD:
C00013 ]
Comment
Isolated from an ecotype of the plant Arabidopsis thaliana from Cape Verde Islands. The enzyme also gives (3E,7E)-dolathalia-3,7,11-triene and traces of other terpenoids. cf. EC
4.2.3.168 dolathalia-3,7,11-triene synthase.
History
EC 4.2.3.167 created 2017
Reference
Authors
Wang Q, Jia M, Huh JH, Muchlinski A, Peters RJ, Tholl D
Title
Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 4.2.3.167