KEGG   ENZYME: 4.2.3.169
Entry
EC 4.2.3.169                Enzyme                                 
Name
7-epi-alpha-eudesmol synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 7-epi-alpha-eudesmol-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = 7-epi-alpha-eudesmol + diphosphate [RN:R11834]
Reaction(KEGG)
R11834
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
7-epi-alpha-eudesmol [CPD:C21689];
diphosphate [CPD:C00013]
Comment
The enzyme, found in the bacterium Streptomyces viridochromogenes, is specific for (2E,6E)-farnesyl diphosphate.
History
EC 4.2.3.169 created 2017
Reference
1  [PMID:27829890]
  Authors
Rabe P, Schmitz T, Dickschat JS
  Title
Mechanistic investigations on six bacterial terpene cyclases.
  Journal
Beilstein J Org Chem 12:1839-1850 (2016)
DOI:10.3762/bjoc.12.173
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.169
IUBMB Enzyme Nomenclature: 4.2.3.169
ExPASy - ENZYME nomenclature database: 4.2.3.169
BRENDA, the Enzyme Database: 4.2.3.169

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Protein sequence (220)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (218)   
DNA sequence (467)   
   RefSeq(nuc) (434)   
   GenBank (19)   
   EMBL (14)   
Protein domain (4)   
   InterPro (4)   
All databases (696)   

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