KEGG   ENZYME: 4.2.3.199
Entry
EC 4.2.3.199                Enzyme                                 
Name
(-)-5-epieremophilene synthase;
STPS1 (gene name);
STP2 (gene name);
STP3 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (-)-epieremophilene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (-)-5-epieremophilene + diphosphate [RN:R12261]
Reaction(KEGG)
R12261
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(-)-5-epieremophilene [CPD:C22045];
diphosphate [CPD:C00013]
Comment
The plant Salvia miltiorrhiza (danshen) produces three different forms of the enzyme, encoded by paralogous genes, that exhibit different spacial expression patterns and respond differently to hormone treatment.
History
EC 4.2.3.199 created 2018
Orthology
K23173  (-)-5-epieremophilene synthase
Genes
SSPL: 121793824 121793826 121793836 121799125 121799283
SMIL: 130991795 130991815 130991817 130991818
SHIS: 125196621 125197048 125197158 125197208 125199782 125216656
Reference
1  [PMID:28487717]
  Authors
Fang X, Li CY, Yang Y, Cui MY, Chen XY, Yang L
  Title
Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining.
  Journal
Front Plant Sci 8:627 (2017)
DOI:10.3389/fpls.2017.00627
  Sequence
[ag:ARM19967 ARM19968 ARM19969]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.199
IUBMB Enzyme Nomenclature: 4.2.3.199
ExPASy - ENZYME nomenclature database: 4.2.3.199
BRENDA, the Enzyme Database: 4.2.3.199

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (18)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (3)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   InterPro (7)   
All databases (38)   

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