KEGG   ENZYME: 4.2.3.46
Entry
EC 4.2.3.46                 Enzyme                                 
Name
alpha-farnesene synthase;
(E,E)-alpha-farnesene synthase;
AFS1;
MdAFS1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate lyase [(3E,6E)-alpha-farnesene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate [RN:R08696]
Reaction(KEGG)
R08696
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(3E,6E)-alpha-farnesene [CPD:C09665];
diphosphate [CPD:C00013]
History
EC 4.2.3.46 created 2010
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K14173  alpha-farnesene synthase
Genes
CPAP110812202
CIT102618658 102625123
CICCICLE_v10014790mg CICLE_v10018045mg
PVY116105216 116107515
MINC123218733 123218734
TCC18597031
GRA105775103
GHI107925033 107941108
GAB108451362
HSYR120174784 120191020
DZI111275141 111278493 111278668 111318785
EGR104429922 104441154 104441155 104442740 104442741 104442742 104442748 104442750 120292434 120292508 120292515 120292516
GMX100805428(TPS27) 100812119(TPS21)
GSJ114374943
PVUPHAVU_011G013600g
VRA106778111
VAR108339494
VUN114170633
VUM124843652
CCAJ109798516 109816863
APRC113865769
MTR11422412
TPRA123924643
CAM101497499
PSAT127106806
VVO131606613
LJALj3g3v3653420.2(Lj3g3v3653420.2)
LANG109353649
PCIN129315248
QSAO6P43_032258 O6P43_032264 O6P43_032265 O6P43_032375
FVE101301453
RCN112202294 112203530
PPER18779527 18780802 18781109
PMUM103324592 103325568 103325630 103325632
PAVI110746466 110760301 110760313 110768757
PDUL117624979 117625783 117625956
MDM103446592
MSYL126586068
ZJU107421480
MNT21397955
CSAV115707439
RCU8267421
JCU105650120
HBR110646158
POP7495294
PEU105107359
PALZ118031650 118031653
JRE109006431 109006432 109006436 109006437 109011554
CILL122278293 122278773 122279849
CAVE132171894 132171897
QSU111988842 111988854 111988873 111989179 111989188
QLO115974000 115992038 115992039
TWL120005010
VVI100240859
VRI117923379
SLY101258440 101260508
SPEN107010686 107010846 107013096
SOT102600675 102604608
SSTN125846823 125848662 125848698
SDUL129872308 129872311 129875112 129895341
CANN107857095 107858222 107859528 107866137
LBB132611312 132612326 132622302 132624614 132625094
NTA107765628 107779472 107800233 107814194
NSY104217013 104242876
NTO104107440 104116491
INI109167313
ITR116030598
SIND105175393
OEU111368535 111368536
EGT105968665
SSPL121746043
SMIL130985658 130985718
LSV111897134
DCR108198720 108199225
CSIN114257853 114266406 114288844
BVG104883054
CQI110687266 110693457
ATRI130815790
MOF131153290
MING122059084 122060221 122067625 122084919
TSS122643319 122672262
 » show all
Reference
1  [PMID:14740213]
  Authors
Pechous SW, Whitaker BD
  Title
Cloning and functional expression of an ( E, E)-alpha-farnesene synthase cDNA from peel tissue of apple fruit.
  Journal
Planta 219:84-94 (2004)
DOI:10.1007/s00425-003-1191-4
  Sequence
[mdm:103446592]
Reference
2  [PMID:19181671]
  Authors
Green S, Squire CJ, Nieuwenhuizen NJ, Baker EN, Laing W
  Title
Defining the potassium binding region in an apple terpene synthase.
  Journal
J Biol Chem 284:8661-9 (2009)
DOI:10.1074/jbc.M807140200
  Sequence
[mdm:103446592]
Reference
3  [PMID:19516075]
  Authors
Nieuwenhuizen NJ, Wang MY, Matich AJ, Green SA, Chen X, Yauk YK, Beuning LL, Nagegowda DA, Dudareva N, Atkinson RG
  Title
Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa).
  Journal
J Exp Bot 60:3203-19 (2009)
DOI:10.1093/jxb/erp162
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.46
IUBMB Enzyme Nomenclature: 4.2.3.46
ExPASy - ENZYME nomenclature database: 4.2.3.46
BRENDA, the Enzyme Database: 4.2.3.46

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