KEGG ENZYME: 4.2.3.75

ENZYME: 4.2.3.75

Entry

EC 4.2.3.75                 Enzyme

Name

(-)-germacrene D synthase

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(-)-germacrene-D-forming]

Reaction(IUBMB)

(2E,6E)-farnesyl diphosphate = (-)-germacrene D + diphosphate [RN:R07648]

Reaction(KEGG)

R07648

Substrate

(2E,6E)-farnesyl diphosphate [CPD:C00448]

Product

(-)-germacrene D [CPD:C16142];
diphosphate [CPD:C00013]

Comment

In Solidago canadensis the biosynthesis results in the pro-R hydrogen at C-1 of the farnesy diphosphate ending up at C-11 of the (-)-germacrene D [1]. With Streptomyces coelicolor the pro-S hydrogen at C-1 ends up at C-11 of the (-)-germacrene D [2].

History

EC 4.2.3.75 created 2011

Pathway

ec00909

Sesquiterpenoid and triterpenoid biosynthesis

Orthology

K10187

germacradienol/geosmin synthase

K15803

(-)-germacrene D synthase

Genes

CRB:

17895797

CSAT:

104723556

BRP:	103842000 108870167

BNA:

106348970

CPAP:

110817191 110819947 110820697 110825305

CIT:	102577959(TPS1) 102606641 102606948 102610978 102613731 102614035 102614827 102616874 102622256 102627944 102631432

PVY:	116105518 116108254 116114296 116114297 116122629 116122670 116123875 116123919 116128727 116129547 116129645 116139294 116139296 116141520 116142915 116142928 116144138

MINC:

123214941 123217276 123218944 123219032 123219039 123219083 123219099 123219113 123226772 123226781 123226790 123226799

TCC:	18593679 18593703 18593710 18593711

GRA:	105776241 105786735 105801286

GHI:	107916720 107925056 107925058 107929750 107929751 107929756 107940014

GAB:	108471338 108472067 108472334 108472792 108472971 108473109 108480662 108488612 108488744 108489065

HSYR:

120127805 120154684 120160262 120163398 120178222

DZI:	111276463 111276468 111276470 111276473 111276474 111288018 111288045 111288053 111288160 111297740 111302305

EGR:

104417793 104422073 104423654 104423657 104426794 104431307 104431518 104434741 104434742 104435118 104438521 104438522 104438524 104439699 104439741 104442836 104443666 104443676 104443681 104445174 104447221 104448991 104450191 104450193 104450195 104452103 108956993 108957023 108957191 108958990 120289312 120293350 120293361 120296133

GMX:	100781367(TPS19) 100794444(TPS16) 100802427

GSJ:	114375760 114378070 114378163 114379503 114379554 114379670

PVU:	PHAVU_011G142600g PHAVU_011G142700g PHAVU_011G142900g PHAVU_011G143100g PHAVU_011G143500g PHAVU_011G143600g PHAVU_011G143700g PHAVU_011G143900g PHAVU_011G144200g

VRA:	106753038 106753988 106755584 106761535 106778564 106778567 106778768 106778773

VAR:	108319866 108322104 108333550 108333638 108339051 108339263

VUN:	114170246 114170247 114170254 114170534 114170536 114170648 114181668 114183647 114185022 114185023

VUM:	124835823 124842047

CCAJ:

109790254 109791106 109792064 109792455 109793071 109793809 109794211 109807319 109809806 109810292 109818105

APRC:

113854954 113855470 113864462 113864625 113864676 113865170 113865523 113865933 113865939

MTR:	11407907 11411115 11416693 11426332 11432484 120575864 120575865 120575943 120575944 120576871 120576874 120576876 120576878 120576881 120576884 120580864 25491517 25492939 25496253 25498399

TPRA:

123882931 123912955 123915196 123918126 123918870 123919508

CAM:	101490280 101490596 101492126 101492760 101494014 101513674

PSAT:

127104189 127106453 127106455 127106717

VVO:	131602444 131607291 131607295 131607302 131611133 131617338 131631667

LJA:	Lj0g3v0102559.1(Lj0g3v0102559.1) Lj0g3v0221889.1(Lj0g3v0221889.1)

ADU:	107462299 107462309 107462311 107462316 107462321 107463346 107478240 107489181 107495385 127741258

AIP:	107610590 107610595 107610600 107610605 107610614 107610617 107610622 107610668 107611639 107611935 107612684 107613526 107614173 107614528 107641830 110265247

AHF:

112697507 112705327 112705328 112705428 112705430 112707273 112707277 112707844 112708424 112708425 112708427 112737713 112750199 112755731 112769094 112769113 112769656 112769662 112770513 112770650 112770960 112770961 112771646 112771648 112771671 112771908 112772214 112773068 112773080 112773092 112773156 112773332 112789842 112804125 114924357

PCIN:

129286409 129286410 129286412 129296640 129299333 129300307 129312473 129316829 129317414 129317727

QSA:	O6P43_000871 O6P43_000872 O6P43_000878 O6P43_000879 O6P43_000882 O6P43_000883 O6P43_001572 O6P43_028974 O6P43_028975

FVE:	101290764 101291476 101295187 101295554 101298810(FVPINS) 101302282 101302497 101303103 101306242 101307161 101310304 101310428 101310591 101311088 101311104 101312536 101312825 101314066 105351835

RCN:

112164470 112166504 112167094 112167493 112167522 112167657 112168229 112169075 112169351 112169746 112169799 112170354 112171168 112177729 112178110 112180170 112181985 112182152 112182576 112182805 112187154 112191281 112191374 112192946 112193616 112194272 112194996 112199362 112201756 112202444 112202768 112203648

PPER:

109946381 109948434 109948455 109948513 109948613 109948626 109948856 109948858 109948872 109948893 109948901 109948960 109949028 18779209 18779436 18779487

PMUM:

103326302 103326362 103326366 103326370 103326375 103326584 103331330 103339449 103342479 103342737 103343924

PAVI:

110745631 110745929 110746130 110752195 110752199 110754995 110757058 110763937 110768307 110772942

PDUL:

117612877 117624233 117624732 117625162 117625373 117625380 117625391 117625394 117625865 117625883 117625886

MDM:	103410286 103416516 103429783 103429813 103448570(PIN/CAM) 103450609 103450622 114819100

MSYL:

126589806 126589807 126590900 126592357 126592358 126592855 126594209 126594210 126594211 126594212 126616057 126616070 126628927

PXB:	103927426 103931167 103931173 103931174 103931185 103934435 103936608 103936614 103938208 103941312 103941383 103946649 103949467

ZJU:	107416144 107416156 107421982 107430474 107431218 107431225 107431236 107431377 107435184 112490604 125418759 125421109 125422115 125422118 125422177 125423950

MNT:	21384665 21392126 21395542 21404011 21404017

CSAV:

115694741 115695419 115695567 115695575 115707304 115724563 115725506

CSV:	101202882 101203434 101207046 101207286 101209789 101210313 101211452 101211540 101211697 101219443

CMO:	103490898 103490985 103491130 103491131 103491132 103493386(TPS) 103493390 103493391(TPS) 103501122 107990967 127150038

BHJ:	120069970 120089925 120090131 120090154 120090543 120090544 120091699 120091719

MCHA:

111012779 111013331 111013399 111013401 111013402 111013811 111021373 111021377 111021378

CMAX:

111483232 111483269 111483273

CMOS:

111435879 111438481 111440345 111449935

CPEP:

111783836 111800136 111809865 111809866

RCU:

8282483

JCU:	105629034 105633233 105633241 105634372 105635753 105640128

HBR:	110640909 110643120 110643161 110645764 110651556 110657408 110657854 110662165 110670038

MESC:

110601592 110602218 110602220 110603527 110603551 110603788 110603796 110607983 110607984 110608853 110609961 110618172 122721908

POP:	18105590 18108164 7454979 7457783 7480434

PEU:	105111852 105111854 105111856 105115913 105119083 105123975 105130095 105133294 105142363

PALZ:

118037045 118037046 118045274 118048703 118049485 118050597 118051015 118051346 118054074 118057068 118057069 118057419 118057420 118058199 118058202 118058367 118058646 118063017 118063018

JRE:	108992229 108999402 109010554 109012609 109013556 109013565 109013659 109013675 109013682 109013691 109013694 109014299 109018572 109021034 118344170

CILL:

122278833 122280511 122280555 122280578 122280632 122281942 122281950 122281968 122282515 122289164 122289401 122301969 122309364 122309390 122309462 122310297 122311326 122311477 122311497 122311621

CAVE:

132161853 132161868 132173750 132174525 132174528 132175956 132176104

QSU:	111985113 111989641 111997266 111997267 111999375 112008800 112011621 112012919 112015023 112016932 112016934 112020915 112020917 112020918 112020927 112031747 112031753 112039852 112040020

QLO:	115954963 115957445 115957462 115957520 115957757 115957857 115958014 115958046 115958093 115964182 115966472 115968176 115968547 115968552 115972803 115989132

TWL:	119985450 119988676 119990402 120002543 120002686 120002687 120003135 120003763 120004609 120011814 120012671

VVI:	100232954 100241381 100241480 100241877 100243606 100252140 100255553 100257265 100258596 100260629 100260714 100261959 100261963 100264159 100267551

VRI:	117905779 117906290 117907643 117908513 117908514 117908693 117908702 117908705 117908721 117908731 117909329 117909404 117909418 117909420 117909463 117909516 117909603

SLY:	100820702(TPS17) 100820703(TPS16) 101245838 101257190 101258081 104648118 104648119

SPEN:

107005350 107017446 107025225 107025236 107025497 107026541

SOT:	102580832 102583484 102590669 102594847 102597519 102598796 102599254 102603252 107059086

SSTN:

125849957 125850664 125856297 125863111 125866312 125875946 125877063 125877065

SDUL:

129871513 129871595 129887112 129892373 129899397 129899657 129900321 129901532

CANN:

107841877 107846955 107848672 107851706 107861170 107863283 107878220

LBB:	132615476 132615560 132620353 132625200 132636736 132641672

NTA:	107787471 107803155 107803193 107805520 107812685 107817699 107819330 107821449 107822502 107828058

NSY:	104210535 104211489 104217721 104219427 104228270 104231187 104233427 104233429 104233433 104240367 104241247 104248559 104249323

NTO:	104087276 104088582 104091009 104103043 104110062 104112006 104115014 104120197

NAU:	109209614 109216542 109222280 109227187 109228645 109229925 109241639 109241781 109243139 109243156 109244294

INI:	109147636 109168993 109175352 109175365 109176145 109176147 109176148 109176149 109176150 109184694 109184695 109184757 109188040

ITR:	115997391 116001494 116001595 116001596 116001597 116002466 116002613 116002793 116003034 116003176 116003177 116003179 116005891 116011349 116019445 116020288 116020289 116021233 116029930

SIND:

105163620 105163683 105171201 105174803 105175135 105175138 105180301

OEU:	111371938 111379384 111379520 111395024 111395052 111395070 111395074 111395633 111395675

EGT:	105948712 105970559

SSPL:

121741308 121743928 121754351 121755182 121755258 121757275 121757277 121757303 121758279 121758409 121775128 121775717 121775718 121804437

SMIL:

130999951 130999952 131009350 131009351 131009352 131020593

SHIS:

125188628 125188692 125192260 125195278 125196686 125196895 125207428 125207881 125219623 125223724

APAN:

127255342 127265926 127266054 127266188

HAN:	110864314 110864605 110864635 110882043 110885547 110890026 110891932 110912423 110914415 110916903 110917082 110917103 110917200 110921325 110922989 110925663 110925783 110929769 110936945 110937991 110943018

ECAD:

122581610

LSV:	111876002 111879199 111881062 111882369 111891777 111897586 111899251 111899252 111899253 111911440 111917144 111921435 111921883

CCAV:

112504089 112505103 112505327 112517783 112517997 112518419 112527555 112527588 112527994 112528199

DCR:	108192917 108194958 108200646 108200937 108202782 108202783 108202786 108205231 108208403 108210657 108211322 108211910 108213517 108216912 108217562

CSIN:

114256887 114266949 114269604 114277960 114294446 114295984 114300069 114309638 114311276 114321578 114321586

RVL:	131307431 131311909 131312061 131323517 131324753 131325996 131327934 131328723 131328740 131328741 131330400 131330401 131330402 131330404 131330556 131330899 131330900 131330901 131330902 131330903 131330904 131330927 131330928 131330930 131330940 131331521

AEW:	130750997 130751352 130751698 130789465 130790210 130792838

BVG:	104896149 104907100 104907120

SOE:	110795055 110797872 110802256

CQI:	110684438 110690773 110690774 110693149 110693172 110693173 110693174 110693176 110696082 110712950 110720079 110720102 110720187 110722126 110729050 110733209

ATRI:

130805421 130807259 130807280 130808267 130817590 130825389 130825527 130828955

MOF:	131143510 131143519 131143525 131153999 131157294 131157857 131157860 131157867

NNU:	104585729 104586487 104590893 104590986 104599064

MING:

122059710 122063872 122078115 122089650

TSS:	122640585 122640965 122652020

OBR:

102717612

BDI:

100842044

ATS:	109777990 109785129 109785753

TDC:	119266613 119279416 119332759 119345243 119358730 119366677

SITA:

101753142 101755633 101777640

PVIR:

120662396 120663935 120663952 120667092 120693440 120700500 120700550 120711729

PDA:

103714132

EGU:	105032396 105035625

MUS:	103974971 103992313

ZOF:

121976856 121989430 121989444 121989994 121990030 121990055 121990068 121990205 121992250 121992308 121992309 121992471 121992474 121992478 121992479 121993824 121993830 121993850 121993885 121993999 121996195 122000228 122001961 122013680 122013691 122013701 122015451 122018980 122033361 122036371 122036690 122038822

DCT:	110093810 110094034 110094036 110094071 110098562 110098584 110100221 110105573 110109817 110110315 110110317 110110327 110110328

PEQ:	110023080 110027151 110027154 110036369 110037117 110038042

AOF:

109837481

MSIN:

131221661 131221662 131221669 131221670 131221692 131229709 131235067 131235377 131235502 131235511 131236080 131238839 131238854 131238893 131240408 131241040 131245475 131245483 131246392 131248564

ATR:

18448295

MXA:

MXAN_6247

MSD:	MYSTI_06763

MYM:	A176_000650

MYX:	QEG98_34370

CCX:	COCOR_07379(cyc2)

MFU:	LILAB_15255

MMAS:

MYMAC_005982

SUR:	STAUR_1114(geoA2)

AGE:	AA314_02305 AA314_08732

AVM:	JQX13_43635

MBD:	MEBOL_001975

CFUS:

CYFUS_002616

SCL:

sce1440

SCU:	SCE1572_16350

CCRO:

CMC5_068260

MRM:	A7982_08001

HOH:

Hoch_1257

NANN:

O0S08_24410 O0S08_35550

NBR:	O3I_014240

NOZ:	DMB37_34650

NAH:	F5544_16725

NTC:	KHQ06_14685

NHU:	H0264_13605

NYA:	LTV02_19175

SPIN:

KV203_07525

SCO:	SCO6073(SC9B1.20)

SALB:

XNR_1297

SMA:	SAVERM_2163(geoA)

SGR:	SGR_6839(geoA)

SGB:

WQO_01005

SFI:

SFUL_319

SANL:

KZO11_00565

SGRF:

SGFS_033720

SCYE:

R2B67_35190

SCB:	SCAB_20121(geoA)

SSX:	SACTE_0245

SVL:	Strvi_9069

SHY:

SHJG_7148

SHO:	SHJGH_6908

SRC:	M271_26075

SMAL:

SMALA_3748

SSOI:

I1A49_22455

SFA:

Sfla_6028

SBH:

SBI_02068

SVE:	SVEN_0269 SVEN_0552

SDV:	BN159_2274(cyc2)

SALS:

SLNWT_0774

STRP:

F750_0540

SCI:	B446_28510

SLV:	SLIV_07775(cyc2)

SGU:	SGLAU_26100

SVT:	SVTN_02895

STRE:

GZL_04447

SCW:	TU94_25990

SLD:

T261_3872

SLC:	SL103_34365

SXI:	SXIM_51240

STRM:

M444_26920

STRC:

AA958_01915

SAMB:

SAM23877_5788(cyc)

SPRI:

SPRI_6965

SCZ:	ABE83_34050

SCX:	AS200_11935

SRW:	TUE45_06695(cyc2)

STRF:

ASR50_27725

SLE:	sle_16070(sle_16070)

SRN:	A4G23_00120(cyc2)

SPAV:

Spa2297_25605

STRT:

A8713_25265

SCLF:

BB341_26965

SGS:	AVL59_11955

STSI:

A4E84_31220

SKY:	D0C37_08035

SALW:

CP975_28380 CP975_33095

SGM:	GCM10017557_17550(cyc2)

SCAD:

DN051_10555

SPHW:

NFX46_09915

SLS:	SLINC_6548

SNR:	SNOUR_19870

SALU:

DC74_4443

SALL:

SAZ_23610

SPLU:

LK06_026700

STRD:

NI25_09000

SNW:	BBN63_17575

SAUO:

BV401_22145

SSIA:

A7J05_08620

SVU:	B1H20_00605

SPUN:

BFF78_10710

SGV:	B1H19_22450

SLAU:

SLA_0172

SALF:

SMD44_07198(cyc2)

SALJ:

SMD11_6421(cyc2)

SLX:	SLAV_09415(cyc1)

STRO:

STRMOE7_21145

SFK:

KY5_6300

SNZ:	DC008_27320

SGE:	DWG14_02009(cyc2)

SRJ:

SRO_1735

SLK:	SLUN_03000

SDX:	C4B68_09160

SGD:	ELQ87_08740

SQZ:	FQU76_00840

SCYA:

EJ357_36215

SAST:

CD934_06110

SNQ:	CP978_26325

STIR:

DDW44_29705

SKA:	CP970_09515

SGZ:	C0216_09490

SVN:	CP980_07125

SNK:	CP967_32685

SHAW:

CEB94_31845

SRK:	FGW37_30680

SFIC:

EIZ62_31190

SGAL:

CP966_28425

SSPO:

DDQ41_30295

SVR:	CP971_17330

SPAD:

DVK44_16910

SAQU:

EJC51_36445

SGF:	HEP81_01918

SCAV:

CVT27_00465

SSEO:

D0Z67_23170

SBY:	H7H31_13965

SRIM:

CP984_29865

SSUB:

CP968_07850

SPHV:

F9278_38075

SCIN:

CP977_03065

SFUG:

CNQ36_25980

SPAC:

B1H29_08340

STSU:

B7R87_32680

SCHA:

CP983_09805

SGX:	H4W23_03680

SCOE:

CP976_33675

SBAT:

G4Z16_14665

SSPB:

CP982_33700

SNF:	JYK04_06546(cyc2)

SPLA:

CP981_20875

SBRO:

GQF42_32880

STUI:

GCM10017668_55740(cyc2)

SATA:

C5746_02905

SCHF:

IPT68_28555

SHUN:

DWB77_03759(cyc2)

SHAR:

HUT13_25895

SCYG:

S1361_30400(cyc2)

SFEU:

IM697_32630

SLIA:

HA039_17755

SDW:	K7C20_20210

SVD:	CP969_29395

SCAL:

I6J39_00730

SAUH:

SU9_018255

SFB:	CP974_00685

SPRA:

CP972_28320

SPEU:

CGZ69_02405

SROI:

IAG44_08725

SGJ:	IAG43_02220

SHK:	J2N69_29585

SANU:

K7396_16690

STRY:

EQG64_00720

SDD:	D9753_07640

SACT:

DMT42_29860

SMAO:

CAG99_12820

SGOB:

test1122_08905 test1122_25330

SINE:

KI385_24560

SLF:	JEQ17_12070

SDEC:

L3078_35570

SAOV:

G3H79_05130

SDUR:

M4V62_08365

SYAN:

NRK68_27210

SRUG:

F0345_21565

SAKB:

K1J60_10395

STAA:

LDH80_05320

SNIG:

HEK616_67550(cyc2)

SVIO:

HWN34_07160

SCAE:

IHE65_09900

STUB:

MMF93_09085

SSPN:

LXH13_30640

SCIR:

STRCI_006311

SXT:	KPP03845_105794(cyc2_1)

SLON:

LGI35_33135

SDRZ:

NEH16_29520

STUD:

STRTU_003254

STEE:

F3L20_12610

SGK:	PET44_25485

SANT:

QR300_22810

SYUN:

MOV08_19910

SARG:

HKX69_07350

SJN:	RI060_08975

SCYN:

N8I84_30570

SOV:	QZH56_33735

SFIY:

F0344_33695

SHAU:

K9S39_12905

SKG:	KJK29_07040

SCOA:

QU709_08660

SLAI:

P8A22_36895

SFP:	QUY26_06250

SCHG:

NRO40_01380

STTN:

BSL84_26640

SINN:

ABB07_08020

STRZ:

OYE22_13780

SCT:	SCAT_2953(cyc)

SCY:	SCATT_29440

KSK:	KSE_46080(geoA)

KAB:	B7C62_00490

KAU:	B6264_12330

KIT:	CFP65_0675 CFP65_6829

KIS:	HUT16_21240

STRI:

C7M71_007765

YIA:	LO772_26615

STRH:

GXP74_15410

AGLA:

OIE69_19960

KFL:

Kfla_4247

NGV:	CDO52_17055

STRR:

EKD16_02015(cyc2)

ACTW:

F7P10_28090

AGRA:

AGRA3207_002480

AMAZ:

LUW76_35960

ACIR:

OG979_26335

SPIQ:

OHA34_15550 OHA34_15730

ACTQ:

OG417_01085

SRO:

Sros_0075

NOA:	BKM31_47430

NOW:	GBF35_49900

NCX:	Nocox_40695(cyc2)

NGN:	LCN96_09125 LCN96_54695

NFS:	OIE67_45720

MHAI:

OHB01_00735

FRA:	Francci3_4231

FRE:	Franean1_5559

FAL:

FRAAL6507

FRI:	FraEuI1c_3502

SEN:	SACE_3187 SACE_3977 SACE_4907

SACG:

FDZ84_36100

AMD:

AMED_1325

AMN:

RAM_06720

AMM:

AMES_1317

AMZ:

B737_1318

AOI:

AORI_7417

AJA:	AJAP_38785

AMYC:

CU254_05185

AMYB:

BKN51_30485

AAB:	A4R43_38405

AMYY:

YIM_39645(cyc2)

AORI:

SD37_03385

AACD:

LWP59_11790

APRT:

MUY14_30005

AROO:

NQK81_28485

ATHM:

L1857_15985

ARHD:

VSH64_44360

APRE:

CNX65_04920

AMI:

Amir_0977

SESP:

BN6_11180(geoA)

SSYI:

EKG83_05700

KAL:	KALB_676 KALB_677

KUT:	JJ691_71460

KBU:	Q4V64_40395

KPHY:

AOZ06_40930

LED:	BBK82_06540

ALO:

CRK56063

PMAD:

BAY61_21455

ACTU:

Actkin_00570(cyc2)

CROS:

N8J89_23320

PSUU:

Psuf_085020(cyc2)

CATI:

CS0771_03970(cyc2)

DVC:	Dvina_35855

DMAT:

Dmats_30680

CAI:

Caci_6200

SNA:

Snas_1127

GLY:	K3N28_04695

AEY:	CDG81_12895

NPU:	Npun_R2756

NED:	HUN01_24355

CSG:	Cylst_4391

CALO:

Cal7507_2995

DHT:	NG743_19380

ALAX:

NIES50_53430

KBS:	EPA93_38090

» show all

Reference

Authors

Schmidt, C.O., Bouwmeester, H.J., Franke, S. and Konig, W.A.

Title

Mechanisms of the biosynthesis of sesquiterpene enantiomers (+)- and (-)-germacrene D in Solidago canadensis.

Journal

Chirality 11:353-362 (1999)

Reference

2 [PMID:14995166]

Authors

He X, Cane DE.

Title

Mechanism and stereochemistry of the germacradienol/germacrene D synthase of Streptomyces coelicolor A3(2).

Journal

J Am Chem Soc 126:2678-9 (2004)
DOI:10.1021/ja039929k

Sequence

[sco:SCO6073]

Reference

3 [PMID:15464152]

Authors

Lucker J, Bowen P, Bohlmann J

Title

Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries.

Journal

Phytochemistry 65:2649-59 (2004)
DOI:10.1016/j.phytochem.2004.08.017

Sequence

[vvi:100232954]

Reference

4 [PMID:15542052]

Authors

Prosser I, Altug IG, Phillips AL, Konig WA, Bouwmeester HJ, Beale MH

Title

Enantiospecific (+)- and (-)-germacrene D synthases, cloned from goldenrod, reveal a functionally active variant of the universal isoprenoid-biosynthesis aspartate-rich motif.

Journal

Arch Biochem Biophys 432:136-44 (2004)
DOI:10.1016/j.abb.2004.06.030

Other DBs

ExplorEnz - The Enzyme Database:

4.2.3.75

IUBMB Enzyme Nomenclature:

4.2.3.75

ExPASy - ENZYME nomenclature database:

4.2.3.75

BRENDA, the Enzyme Database:

4.2.3.75

DBGET integrated database retrieval system