Entry |
|
Name |
(-)-alpha-cuprenene synthase;
Cop6
|
Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
|
Sysname |
(-)-alpha-cuprenene hydrolase [cyclizing, (-)-alpha-cuprenene-forming]
|
Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate = (-)-alpha-cuprenene + diphosphate [RN: R09895]
|
Reaction(KEGG) |
|
Substrate |
(2E,6E)-farnesyl diphosphate [CPD: C00448]
|
Product |
|
Comment |
The enzyme from the fungus Coprinopsis cinerea produces (-)-alpha-cuprenene with high selectivity.
|
History |
EC 4.2.3.95 created 2012
|
Orthology |
K22060 | (-)-alpha-cuprenene synthase |
|
Genes |
|
Reference |
|
Authors |
Lopez-Gallego F, Agger SA, Abate-Pella D, Distefano MD, Schmidt-Dannert C |
Title |
Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 4.2.3.95 |
ExPASy - ENZYME nomenclature database: | 4.2.3.95 |
|