KEGG   ENZYME: 4.2.99.22
Entry
EC 4.2.99.22                Enzyme                                 
Name
tuliposide A-converting enzyme;
tuliposide-converting enzyme;
6-O-(4'-hydroxy-2'-methylenebutyryl)-D-glucose acyltransferase (lactone-forming);
TCA;
TCEA
Class
Lyases;
Carbon-oxygen lyases;
Other carbon-oxygen lyases
Sysname
6-tuliposide A D-glucose-lyase (tulipalin-A-forming)
Reaction(IUBMB)
6-tuliposide A = tulipalin A + D-glucose [RN:R10494]
Reaction(KEGG)
R10494
Substrate
6-tuliposide A [CPD:C20577]
Product
tulipalin A [CPD:C20578];
D-glucose [CPD:C00031]
Comment
Isolated from the plant Tulipa gesneriana (tulip). The reaction is an intramolecular transesterification producing the lactone. The enzyme also has a weak activity with 6-tuliposide B and 6-O-benzoyl-D-glucose.
History
EC 4.2.99.22 created 2013
Orthology
K20506  tuliposide A-converting enzyme
Reference
1  [PMID:19661715]
  Authors
Kato Y, Shoji K, Ubukata M, Shigetomi K, Sato Y, Nakajima N, Ogita S
  Title
Purification and characterization of a tuliposide-converting enzyme from bulbs of Tulipa gesneriana.
  Journal
Biosci Biotechnol Biochem 73:1895-7 (2009)
DOI:10.1271/bbb.90226
Reference
2  [PMID:22474185]
  Authors
Nomura T, Ogita S, Kato Y
  Title
A novel lactone-forming carboxylesterase: molecular identification of a tuliposide A-converting enzyme in tulip.
  Journal
Plant Physiol 159:565-78 (2012)
DOI:10.1104/pp.112.195388
  Sequence
[ag:BAM20978 BAM20979]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.99.22
IUBMB Enzyme Nomenclature: 4.2.99.22
ExPASy - ENZYME nomenclature database: 4.2.99.22
BRENDA, the Enzyme Database: 4.2.99.22

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
Protein sequence (210)   
   UniProt (204)   
   SWISS-PROT (6)   
Protein domain (3)   
   InterPro (3)   
All databases (222)   

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