KEGG ENZYME: 4.3.1.27

ENZYME: 4.3.1.27

Entry

EC 4.3.1.27                 Enzyme

Name

threo-3-hydroxy-D-aspartate ammonia-lyase;
D-threo-3-hydroxyaspartate dehydratase

Class

Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases

Sysname

threo-3-hydroxy-D-aspartate ammonia-lyase (oxaloacetate-forming)

Reaction(IUBMB)

threo-3-hydroxy-D-aspartate = oxaloacetate + NH3 [RN:R09683]

Reaction(KEGG)

R09683

Substrate

threo-3-hydroxy-D-aspartate [CPD:C19813]

Product

oxaloacetate [CPD:C00036];
NH3 [CPD:C00014]

Comment

A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Delftia sp. HT23, also has activity against L-threo-3-hydroxyaspartate, L-erythro-3-hydroxyaspartate, and D-serine. Different from EC 4.3.1.20, erythro-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.16, threo-3-hydroxy-L-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Co2+ or Ni2+.

History

EC 4.3.1.27 created 2011

Orthology

K20757

threo-3-hydroxy-D-aspartate ammonia-lyase

Genes

DAC:

Daci_0971