KEGG   ENZYME: 4.8.1.7
Entry
EC 4.8.1.7                  Enzyme                                 
Name
phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase;
TFP (gene name) (ambiguous);
thiocyanate-forming protein (ambiguous)
Class
Lyases;
Nitrogen-oxygen lyases;
Hydro-lyases
Sysname
phenyl-N-(sulfonatooxy)methanimidothioate sulfate-lyase (benzylthiocyanate-forming)
Reaction(IUBMB)
phenyl-N-(sulfonatooxy)methanimidothioate = benzylthiocyanate + sulfate [RN:R13132]
Reaction(KEGG)
R13132
Substrate
phenyl-N-(sulfonatooxy)methanimidothioate [CPD:C22640]
Product
benzylthiocyanate;
sulfate [CPD:C00059]
Comment
The enzyme, characterized from the plant Lepidium sativum, is involved in the breakdown of the glucosinolate glucotropaeolin. Depending on the substrate, it can also form simple nitrile- and epithionitrile-containing products. cf. EC 4.8.1.5, thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming), and EC 4.8.1.6, N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming).
History
EC 4.8.1.7 created 2022
Orthology
K26382  phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase
Reference
1  [PMID:17139450]
  Authors
Burow M, Bergner A, Gershenzon J, Wittstock U.
  Title
Glucosinolate hydrolysis in Lepidium sativum--identification of the thiocyanate-forming protein.
  Journal
Plant Mol Biol 63:49-61 (2007)
DOI:10.1007/s11103-006-9071-5
  Sequence
[ag:ABD73013]
Other DBs
ExplorEnz - The Enzyme Database: 4.8.1.7
IUBMB Enzyme Nomenclature: 4.8.1.7
ExPASy - ENZYME nomenclature database: 4.8.1.7
BRENDA, the Enzyme Database: 4.8.1.7

  All links  
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   InterPro (2)   
All databases (10)   

Download RDF
DBGET integrated database retrieval system