KEGG ENZYME: 4.99.1.10

ENZYME: 4.99.1.10

Entry

EC 4.99.1.10                Enzyme

Name

magnesium dechelatase;
SGR (gene name);
SGRL (gene name);
Mg-dechelatase

Class

Lyases;
Other lyases;
Sole sub-subclass for lyases that do not belong in the other subclasses

Sysname

chlorophyll a magnesium lyase

Reaction(IUBMB)

(1) chlorophyll a + 2 H+ = pheophytin a + Mg2+ [RN:R08584];
(2) chlorophyllide a + 2 H+ = pheophorbide a + Mg2+ [RN:R09033]

Reaction(KEGG)

R08584 R09033

Substrate

chlorophyll a [CPD:C05306];
H+ [CPD:C00080];
chlorophyllide a [CPD:C02139]

Product

pheophytin a [CPD:C05797];
Mg2+ [CPD:C00305];
pheophorbide a [CPD:C18021]

Comment

Inhibited by Ca2+, Mg2+ and especially Hg2+. SGR has very low activity with chlorophyllide a and none with chlorophyll b. It acts on chlorophyll a both in its free form and in protein complex. SGRL, on the other hand, is more active with chlorophyllide a than with chlorophyll a. The magnesium formed is scavenged by MCS (metal-chelating substance).

History

EC 4.99.1.10 created 2017

Pathway

ec00860

Porphyrin metabolism

ec01110

Biosynthesis of secondary metabolites

Orthology

K22013

magnesium dechelatase

Genes

ATH:	AT1G44000 AT4G11910 AT4G11911 AT4G22920(NYE1)

ALY:	110227542 9303816 9310800 9330036

CRB:	17880941 17882664 17898091

CSAT:

104707485 104707486 104718013 104718062 104718066 104722741 104731201 104737198 104737199 104742156 104757939 104777551

EUS:	EUTSA_v10011724mg EUTSA_v10025991mg EUTSA_v10028881mg EUTSA_v10029210mg

BRP:	103834271 103847714 103858612 103860469(NYE1) 103861346

BNA:	106368456 106375753 106375754 106379154 106388569 106405908 106411225 106416069 106438786 106440469 111197916

BOE:	106296745 106306852 106311628 106325928 106332354 106332703

RSZ:	108810996 108820491 108820492 108820494 108843007 108844784 108846175 108849663 108849678

THJ:	104801615 104813011 104814157

CPAP:

110817458 110818153

CIT:	102607042 102625350

CIC:	CICLE_v10002160mg CICLE_v10021651mg

PVY:	116135361 116138000

MINC:

123203048 123204564 123211317 123229230

TCC:	18592454 18606423

GRA:	105789173 105792158 105797117

GHI:	107910395 107915295 107926912 107929203 107929996 107951459 107963689

GAB:	108468973 108475537 108482352

HSYR:

120117375 120139976 120142869 120163535 120166864 120191113 120203617 120218561

DZI:	111277574 111290791 111305955 111311217

EGR:	104443756 104449661

GMX:	100780387 100783248 100792871 100795181 732541(SGR2) 732647(SGR1)

GSJ:	114377595 114391897 114393255 114410371 114415466 114424266

PVU:	PHAVU_002G153100g PHAVU_009G132100g

VRA:	106776916 106778818

VAR:	108330991 108335192

VUN:	114162819 114173885

VUM:	124835055 124835056 124836970

CCAJ:

109800609 109804690

APRC:

113851144 113853161 113869257

MTR:	11441009 25489732

TPRA:

123908863 123909368

CAM:	101506979 101509366

PSAT:

127082731

VVO:	131632585 131652420 131655683

LJA:	Lj1g3v0900940.1(Lj1g3v0900940.1) Lj2g3v2003030.1(Lj2g3v2003030.1) Lj4g3v1287250.1(Lj4g3v1287250.1) Lj4g3v1327600.1(Lj4g3v1327600.1)

ADU:	107460607 107488169 107489309

AIP:	107605991 107618299 107642980

AHF:	112706005 112722274 112749554 112764929 112800846 112805413

LANG:

109331955 109331956 109332267 109344325 109348932 109362567

PCIN:

129294262 129311495

QSA:	O6P43_015101 O6P43_024250

FVE:	101291680 101309347

RCN:	112173708 112176610

PPER:

18768837 18778046

PMUM:

103337376 103342717

PAVI:

110747541 110763612 110769037

PDUL:

117628671 117637760

MDM:	103444765 114823090 114824730

MSYL:

126619455 126620934 126625108

PXB:	103938096 103938102 103952867 103956540

ZJU:

107423441

MNT:	21395814 21405919

CSAV:

115716985 115723236

CSV:	101206296 101219336

CMO:	103482692 103485669

BHJ:	120068030 120075133

MCHA:

111011794 111023234

CMAX:

111486879 111489764 111491161

CMOS:

111445411 111459528 111461394

CPEP:

111795404 111805902 111809060

RCU:	8270942 8272496

JCU:	105639018 105645904

HBR:	110640007 110646425 110649907 110669045

MESC:

110603639 110606316 110621067

POP:	18099608 7465829 7466435 7478087

PEU:	105112324 105128975 105132188

PALZ:

118028540 118029299 118033782 118033793

JRE:	108980093 108990686 108990827 109010899

CILL:

122280494 122290255 122296301 122298593

CAVE:

132175288 132184735

QSU:	111989332 112030813

QLO:	115962097 115962147

TWL:	119980726 119996870 119997914 120017095

VVI:	100252353 100265112

VRI:	117905826 117906021 117927199

SLY:	101252980 101258237 778212(SGR1)

SPEN:

107006840 107018015 107027953

SOT:	102586926 102597935 102599319

SSTN:

125842119 125854231 125863168

SDUL:

129889350 129889956 129904044

CANN:

107849956 107866321 107867750

LBB:	132603860 132627192 132634993

NTA:	107763781 107780670 107804241 107817134 107818616 107819767 107824323

NSY:	104224916 104245095 104248440

NTO:	104097631 104101412 104101414 104117176

NAU:	109222385 109229634 109235637 109238401 109240001

INI:	109151097 109153247 109183467

ITR:	116018990 116026596 116027337

SIND:

105157242 105159434 105180060

OEU:	111368827 111379051 111397487 111407518

EGT:	105958581 105963408

SSPL:

121769405 121772425 121779761 121785958 121788883 121793744 121800140 121810882

SMIL:

130994634 130994644 131011797 131026493

SHIS:

125193596 125205617 125217062 125222570

APAN:

127243656 127246701 127250678

HAN:	110864360 110864361 110921816 110941208

ECAD:

122578174 122578492 122582843

LSV:	111901931 111920775

CCAV:

112502612 112521276 112527422

DCR:	108192640 108205944 108206688 108216602

CSIN:

114262638 114274922 114288037 114288212 114303382 114303859

RVL:	131331846 131331847

AEW:	130753041 130758024 130758687 130765283 130776665 130793708

BVG:	104892367 104894688

SOE:	110782028 110784352

CQI:	110685908 110702530 110719427 110725760

ATRI:

130800522 130803937 130811507

MOF:	131161650 131164648

NNU:	104596219 104599529 104608345

MING:

122062554 122094258

TSS:	122665171 122667503 122668442

PSOM:

113272243 113275025 113302415 113305294 113346460 113356451

OSA:

4347672

DOSA:

Os04t0692600-01(Os04g0692600) Os09t0532000-01(Os09g0532000)

OBR:

102711183

OGL:	127759582 127783900

BDI:	100822302 100837300

ATS:	109750543 109757653

TDC:	119302596 119311272 119357340 119366651

TAES:

123055433 123104541 123112817 123122300 123175465 123191256

TUA:	125510103 125540489

LPER:

127302582 127345910

LRD:	124654598 124661652 124665453

SBI:	8054896 8073690

ZMA:	100192013 606425 606426

SITA:

101765893 106804238

SVS:	117843798 117848460

PVIR:

120642225 120661350 120683068 120685287

PHAI:

112881901 112901722

PDA:	103716073 103718704

EGU:	105034133 105034966

MUS:	103971055 103973357 103979345 103993530

ZOF:	121983394 121983395 122039859 122042644 122047150 122049295

DCT:	110099840 110102081

PEQ:	110019890 110025696

AOF:

109821600

MSIN:

131233398 131236561 131249054

NCOL:

116248984 116260051

ATR:	18424250 18436871

SMO:	SELMODRAFT_15573 SELMODRAFT_15575

PPP:	112273408 112279759 112286188 112294044

CSL:	COCSUDRAFT_61770

CVR:	CHLNCDRAFT_142305

APRO:

F751_5480

OLU:	OSTLU_27130 OSTLU_29779

OTA:	OT_ostta13g01560

BPG:	Bathy17g02020

MIS:	MICPUN_101002

MPP:	MICPUCDRAFT_48109(JGI:MicpuC2_48109)

» show all

Reference

1 [PMID:11204197]

Authors

Tang L, Okazawa A, Fukusaki E, Kobayashi A

Title

Removal of magnesium by Mg-dechelatase is a major step in the chlorophyll-degrading pathway in Ginkgo biloba in the process of autumnal tints.

Journal

Z Naturforsch C 55:923-6 (2000)
DOI:10.1515/znc-2000-11-1213

Reference

Authors

Costa, M.A., Civello, P.M., Chaves, A.R. and Martinez, G.A.

Title

Characterization of Mg-dechelatase activity obtained from Fragaria x ananassa fruit.

Journal

Plant Physiol Biochem 40:111-118 (2002)

Reference

3 [PMID:15154496]

Authors

Wang T, Quisenberry SS, Ni X, Tolmay V

Title

Enzymatic chlorophyll degradation in wheat near-isogenic lines elicited by cereal aphid (Homoptera: Aphididae) feeding.

Journal

J Econ Entomol 97:661-7 (2004)
DOI:10.1603/0022-0493-97.2.661

Reference

4 [PMID:15890522]

Authors

Suzuki T, Kunieda T, Murai F, Morioka S, Shioi Y

Title

Mg-dechelation activity in radish cotyledons with artificial and native substrates, Mg-chlorophyllin a and chlorophyllide a.

Journal

Plant Physiol Biochem 43:459-64 (2005)
DOI:10.1016/j.plaphy.2005.03.009

Reference

Authors

Kunieda, T., Amano, T. and Shioi, Y.

Title

Search for chlorophyll degradation enzyme, Mg-dechelatase, from extracts of Chenopodium album with native and artificial substrates.

Journal

Plant Sci 169:177-183 (2005)

Reference

6 [PMID:27604697]

Authors

Shimoda Y, Ito H, Tanaka A

Title

Arabidopsis STAY-GREEN, Mendel's Green Cotyledon Gene, Encodes Magnesium-Dechelatase.

Journal

Plant Cell tpc.00428.2016 (2016)
DOI:10.1105/tpc.16.00428

Sequence

[ath:AT4G22920 AT4G11910 AT1G44000]

Other DBs

ExplorEnz - The Enzyme Database:

4.99.1.10

IUBMB Enzyme Nomenclature:

4.99.1.10

ExPASy - ENZYME nomenclature database:

4.99.1.10

BRENDA, the Enzyme Database:

4.99.1.10

DBGET integrated database retrieval system