KEGG ENZYME: 5.1.1.16

ENZYME: 5.1.1.16

Entry

EC 5.1.1.16                 Enzyme

Name

protein-serine epimerase;
protein-serine racemase

Class

Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives

Sysname

[protein]-serine epimerase

Reaction(IUBMB)

[protein]-L-serine = [protein]-D-serine [RN:R05175]

Reaction(KEGG)

R05175

Substrate

[protein]-L-serine [CPD:C06395]

Product

[protein]-D-serine [CPD:C06396]

Comment

The enzyme specifically interconverts the configuration of Ser-46 of the peptide omega-agatoxin-KT, found in the venom of the funnel web spider, Agelenopsis aperta, but not that of the other serine residue, Ser-28.

History

EC 5.1.1.16 created 1999

Reference

1 [PMID:7622482]

Authors

Shikata Y, Watanabe T, Teramoto T, Inoue A, Kawakami Y, Nishizawa Y, Katayama K, Kuwada M.

Title

Isolation and characterization of a peptide isomerase from funnel web spider venom.

Journal

J Biol Chem 270:16719-23 (1995)
DOI:10.1074/jbc.270.28.16719

Other DBs

ExplorEnz - The Enzyme Database:

5.1.1.16

IUBMB Enzyme Nomenclature:

5.1.1.16

ExPASy - ENZYME nomenclature database:

5.1.1.16

BRENDA, the Enzyme Database:

5.1.1.16

CAS:	169592-52-3

All links

Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (1)   
   PDBSTR (1)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
All databases (17)   

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