Entry
Name
isoleucine 2-epimerase;
BCAA racemase
Class
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
BRITE hierarchy
Sysname
isoleucine 2-epimerase
Reaction(IUBMB)
L-isoleucine = D-allo-isoleucine [RN:
R11078 ]
Reaction(KEGG)
Substrate
Product
D-allo-isoleucine [CPD:
C21092 ]
Comment
A pyridoxal phosphate protein. The enzyme, characterized from the bacterium Lactobacillus buchneri, specifically catalyses racemization of nonpolar amino acids at the C-2 position.
History
EC 5.1.1.21 created 2015
Orthology
Genes
» show all
Taxonomy
Reference
Authors
Mutaguchi Y, Ohmori T, Wakamatsu T, Doi K, Ohshima T
Title
Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.1.1.21
ExPASy - ENZYME nomenclature database: 5.1.1.21