KEGG ENZYME: 5.1.3.41

ENZYME: 5.1.3.41

Entry

EC 5.1.3.41                 Enzyme

Name

fructoselysine 3-epimerase;
frlC (gene name)

Class

Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives

Sysname

D-fructosyl-L-lysine 3-epimerase

Reaction(IUBMB)

N6-(D-fructosyl)-L-lysine = N6-(D-psicosyl)-L-lysine [RN:R11720]

Reaction(KEGG)

R11720

Substrate

N6-(D-fructosyl)-L-lysine [CPD:C16488]

Product

N6-(D-psicosyl)-L-lysine [CPD:C21616]

Comment

The enzyme, characterized from the bacterium Escherichia coli, is involved in the catabolism of fructoseamines, amino acid sugar complexes that are formed non-enzymically.

History

EC 5.1.3.41 created 2017

Orthology

K10709

fructoselysine 3-epimerase

Genes

ECO:	b4474(frlC)

ECJ:	JW5699(frlC)

ECD:	ECDH10B_3548(frlC)

EBW:	BWG_3064(frlC)

ECOK:

ECMDS42_2819(frlC)

ECOC:

C3026_18310

ECE:

Z4733

ECS:	ECs_4223(frlC)

ECF:	ECH74115_4684

ETW:	ECSP_4330(frlC)

ELX:	CDCO157_3964

EOI:	ECO111_4182(frlC)

EOJ:	ECO26_4461(frlC)

EOH:	ECO103_4091(frlC)

ESL:

O3K_02205

ESO:

O3O_23445

ESM:

O3M_02250

ECK:	EC55989_3778(frlC)

EOK:	G2583_4078(frlC)

ELR:	ECO55CA74_19465

ELH:

ETEC_3623

ECW:	EcE24377A_3842

EUN:	UMNK88_4138

ECOA:

APECO78_20655

ECX:	EcHS_A3568

ECY:

ECSE_3634

ECR:	ECIAI1_3511(frlC)

EBR:	ECB_03223(frlC)

ECOB:

C3029_20870

EBL:	ECD_03223(frlC)

EBE:	B21_03175(frlC)

EBD:

ECBD_0376

ELO:	EC042_3634(frlC)

ECL:	EcolC_0340

EKO:	EKO11_0372

EKF:	KO11_05935(frlC)

EDH:	EcDH1_0340

EDJ:	ECDH1ME8569_3252(frlC)

ELW:	ECW_m3628(frlC)

ELL:	WFL_17720(frlC)

ELP:	P12B_c3471(frlC)

ECOL:

LY180_17295

ERUY:

OSH18_11020(frlC)

SFL:	SF3391(yhfP)

SFX:	S4371(yhfP)

SFV:	SFV_3378(yhfP)

SFE:	SFxv_3702(frlC)

SFN:

SFy_4818

SFS:

SFyv_4893

SFT:	NCTC1_03672

SSN:	SSON_3504(yhfP)

SBO:	SBO_3360(yhfP)

SBC:	SbBS512_E3750

SHQ:	A0259_20610

ESA:

ESA_04363

CSK:	ES15_0290(frlC)

CSZ:	CSSP291_20095

CSJ:	CSK29544_01248

CDM:	AFK67_19045

CSI:	P262_00433

CMJ:	AFK66_001495

CUI:	AFK65_18215

CMW:	AFK63_00185

CTU:	CTU_38890(frlC)

KQV:	B8P98_28520

CFAR:

CI104_01835

AHN:	NCTC12129_00402(frlC)

ASUB:

NLZ15_01650(frlC)

KIN:	AB182_27500

PDZ:	HHA33_04275(frlC)

METY:

MRY16398_04140(frlC)

EBC:	C2U52_10305

SFW:	WN53_23550

TSY:	THSYN_14985

MAM:	Mesau_02912

SMI:	BN406_03681

SMD:

Smed_5464

SAME:

SAMCFNEI73_pC1597

EAH:	FA04_29320

AGT:	EYD00_23535

RPUS:

CFBP5875_23590 CFBP5875_23745

REP:	IE4803_CH03660 IE4803_CH03683

ROY:	G3A56_16605

RBAN:

J2J98_24600

SSUM:

Q9314_25070

OPS:	A8A54_22960

BPSN:

NIK97_18415

OCH:	CES85_3120

OCR:	HGK82_23080

DEI:	C4375_04045

RSP:	RSP_3944(frlC)

RSQ:	Rsph17025_3648

RSK:	RSKD131_4344

CAZT:

LV780_17505

RCP:	RCAP_rcp00008(frlC)

PARS:

DRW48_05630

PAAK:

FIU66_17075

PSAP:

JHX88_17590

DAA:	AKL17_2270

GUR:

Gura_2524

DTI:	Desti_4344

BMYC:

DJ92_4753

BTRO:

FJR70_05965

BIF:	N288_22690

BSM:	BSM4216_1283

BACQ:

DOE78_09280 DOE78_19815 DOE78_24375

BCOH:

BC6307_07065

BCIR:

C2I06_15330 C2I06_21510

APAK:

AP3564_15365

BSJ:	UP17_08910

PFRI:

L8956_09415

NDT:	L1999_13760 L1999_28455

NCM:	QNK12_02350 QNK12_30185

MEKU:

HUW50_21690

GAJ:	MY490_01345

DOM:	RRU94_06235 RRU94_16930

BLR:	BRLA_c023130

BCHS:

JNE38_06930

BHUI:

LOK74_17980

PPM:	PPSC2_02760(frlC1) PPSC2_08145(frlC3)

PPO:	PPM_0493(frlC1) PPM_1543(frlC3)

PPQ:	PPSQR21_005260(iolE)

PPOY:

RE92_04035 RE92_09185

PMS:	KNP414_05706 KNP414_07068

PMQ:	PM3016_5048 PM3016_6660

PMW:	B2K_26165 B2K_33645

PGM:	PGRAT_32025

PRI:

PRIO_4889

PSON:

JI735_08250 JI735_32095

PIB:	BBD41_28600

PCHI:

PC41400_26480

PTRI:

KDC22_26600

PMAE:

LMZ02_11870 LMZ02_14730

PSPN:

L1F29_23085

PKP:	SK3146_04873

NTR:	B0W44_09930

EAV:	EH197_13545

VTE:	BHY08_05675

CCAA:

KQH81_14645

CMAH:

C1I91_18305

FPLA:

A4U99_15735 A4U99_15740

VCOP:

MM50RIKEN_01950 MM50RIKEN_01960

ACOL:

K5I23_06645

PETR:

QKW49_09090

CAPR:

EQM14_03785

CFEM:

HCR03_02555 HCR03_07460(frlC)

IBU:	IB211_00306 IB211_00950c

LACY:

A4V08_11235

CHYL:

CE91St63_25290

CSH:	Closa_1465 Closa_1473

CSO:	CLS_33510 CLS_33520

BPRL:

CL2_05420

ARF:	AR1Y2_0593

ACAC:

EYQ97_13965

ACHT:

bsdcttw_02070 bsdcttw_19460(frlC)

RGN:	RGna_06855 RGna_06930 RGna_06935

CBOL:

CGC65_02990 CGC65_03760 CGC65_24980 CGC65_24990

CASP:

NQ535_00775 NQ535_13775(frlC)

LBW:	C3V36_04475

GFE:	Gferi_09755

TEP:	TepRe1_1828

TAE:	TepiRe1_1969

HALS:

D7D81_15615

CSC:

Csac_0396

MHAP:

JFY71_04150

HOV:	EQF90_001445

ERH:

ERH_1397

ERS:	K210_05365

ERI:	EEI45_02875

LCG:	L3BBH23_18670

ERB:	A4V01_00500 A4V01_21185

CIU:	G4D55_00095 G4D55_18680 G4D55_19630

OLS:	Olsu_0468 Olsu_1404 Olsu_1413

TIO:	INP52_06235 INP52_06945

CGO:	Corgl_0705

CAER:

CSV91_06665

SGU:	SGLAU_31065

SHK:	J2N69_33310

MCW:	A8L33_05045

MAUR:

BOH66_14845

MNF:	JSY13_12360

LEU:	Leucomu_00620

LTN:	KVY00_09990

GMI:	NMP99_15465

GMY:

XH9_05265

NOA:	BKM31_09025

NOW:	GBF35_46610

NGN:	LCN96_32475

KBS:	EPA93_13640

AMOB:

HG15A2_04410

HBS:	IPV69_04005

SSM:	Spirs_0763

HALJ:

G9465_10360

HGI:	ABY42_16635

HALG:

HUG10_09075

HALU:

HUG12_20655

HALY:

HYG82_03575

HDA:	BB347_12065

NCT:

NMSP_0163

NIC:	DSQ20_00935

» show all

Reference

1 [PMID:14641112]

Authors

Wiame E, Van Schaftingen E

Title

Fructoselysine 3-epimerase, an enzyme involved in the metabolism of the unusual Amadori compound psicoselysine in Escherichia coli.

Journal

Biochem J 378:1047-52 (2004)
DOI:10.1042/BJ20031527

Sequence

[eco:b4474]

Other DBs

ExplorEnz - The Enzyme Database:

5.1.3.41

IUBMB Enzyme Nomenclature:

5.1.3.41

ExPASy - ENZYME nomenclature database:

5.1.3.41

BRENDA, the Enzyme Database:

5.1.3.41

DBGET integrated database retrieval system