Entry
Name
dihydroneopterin triphosphate 2'-epimerase;
D-erythro-7,8-dihydroneopterin triphosphate epimerase;
folX (gene name)
Class
Isomerases;
Racemases and epimerases;
Acting on other compounds
BRITE hierarchy
Sysname
7,8-dihydroneopterin 3'-triphosphate 2'-epimerase
Reaction(IUBMB)
7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate [RN:
R11082 ]
Reaction(KEGG)
Substrate
7,8-dihydroneopterin 3'-triphosphate [CPD:
C04895 ]
Product
7,8-dihydromonapterin 3'-triphosphate [CPD:
C21094 ]
Comment
The enzyme, found in gammaproteobacteria, has almost no activity with 7,8-dihydroneopterin [2].
History
EC 5.1.99.7 created 2015
Pathway
Orthology
K07589 D-erythro-7,8-dihydroneopterin triphosphate epimerase
Genes
ECOO : ECRM13514_3060(folX)
ECOH : ECRM13516_3004(folX)
ELR : ECO55CA74_14075(folX)
ECW : EcE24377A_2597(folX)
EDJ : ECDH1ME8569_2241(folX)
ECOI : ECOPMV1_02462(folX)
REE : electrica_01448(folX)
RTG : NCTC13098_01955(folX)
CLAP : NCTC11466_01285(folX)
KIE : NCTC12125_00374(folX)
AHN : NCTC12129_01509(folX)
METY : MRY16398_16010(folX)
PSHI : SAMEA2665130_1054(folX)
SMW : SMWW4_v1c34360(folX)
SERS : SERRSCBI_16670(folX)
SFJ : SAMEA4384070_3446(folX)
SOF : NCTC11214_03350(folX)
PAQU : DMB82_0007360(folX)
PAEB : NCGM1900_2832(folX)
PRE : PCA10_27810(folX) PCA10_47630(folX)
PNT : G5B91_26470(folX) G5B91_27610(folX)
PSAV : PSA3335_08855(folX)
PPRC : PFLCHA0_c09630(folX)
PFC : PflA506_4451(folB_1)
PMUD : NCTC8068_00953(folX)
PFW : PF1751_v1c46080(folX)
PFF : PFLUOLIPICF712975(folX)
PPUU : PputUW4_00809(folX)
PTRT : HU722_0024545(folX)
PTW : TUM18999_50760(folX)
PTAE : NCTC10697_03608(folX)
PPHN : HU825_09675(folX) HU825_13755(folX)
PSZ : PSTAB_1039(folB) PSTAB_1870(folB)
PSR : PSTAA_1096(folX-1) PSTAA_2002(folX-2)
PSC : A458_10945(folX) A458_16080(folX)
PSH : Psest_2387 Psest_3205
PSTU : UIB01_12130(folX) UIB01_16485(folX)
PCHL : LLJ08_11405(folX) LLJ08_15515(folX)
PBM : CL52_09880(folX) CL52_15725(folX)
PKG : LW136_11070(folX) LW136_16610(folX)
SDEG : GOM96_00755(folX) GOM96_15015(folX)
PZD : KQ248_15405(folX) KQ248_21115(folX)
MSHE : MAALD49_37620(folX)
SLJ : EGC82_05115 EGC82_08340
SPOL : FH971_03490(folX) FH971_07045(folX)
SAES : HBH39_03535(folX) HBH39_10425(folX)
SCAA : TUM17387_16170(folX)
SGLA : FJ709_03530(folX) FJ709_11680(folX)
SINV : K8B83_06090(folX) K8B83_15855(folX)
SVM : KDH10_000395(folX) KDH10_002310(folX)
SPSJ : K0I62_00225(folX) K0I62_07190(folX)
SPSR : EGC80_00795 EGC80_13155
PLZ : S4054249_20265(folX)
SALH : HMF8227_01222(folX)
ASEM : NNL22_01170(folX) NNL22_17280(folX)
SYP : SYNPCC7002_A0307(folB)
SYNN : NIES970_08670(folB)
» show all
Taxonomy
Reference
Authors
Ahn C, Byun J, Yim J
Title
Purification, cloning, and functional expression of dihydroneopterin triphosphate 2'-epimerase from Escherichia coli.
Journal
Sequence
Reference
Authors
Haussmann C, Rohdich F, Schmidt E, Bacher A, Richter G
Title
Biosynthesis of pteridines in Escherichia coli. Structural and mechanistic similarity of dihydroneopterin-triphosphate epimerase and dihydroneopterin aldolase.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.1.99.7
ExPASy - ENZYME nomenclature database: 5.1.99.7