KEGG ENZYME: 5.3.1.33

ENZYME: 5.3.1.33

Entry

EC 5.3.1.33                 Enzyme

Name

L-erythrulose-1-phosphate isomerase;
eryH (gene name)

Class

Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds

Sysname

L-erythrulose-1-phosphate isomerase

Reaction(IUBMB)

L-erythrulose 1-phosphate = D-erythrulose 4-phosphate [RN:R11332]

Reaction(KEGG)

R11332

Substrate

L-erythrulose 1-phosphate [CPD:C03394]

Product

D-erythrulose 4-phosphate [CPD:C03604]

Comment

The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.

History

EC 5.3.1.33 created 2016

Orthology

K21910

L-erythrulose 1-phosphate isomerase

Genes

KPU:

KP1_2114

KPP:

A79E_3110

KPZ:	KPNIH27_09450

KPV:	KPNIH29_09995

KPY:	KPNIH31_09900

KPT:	VK055_1343(tpiA)

KPO:	KPN2242_08665(tpiA)

KPR:

KPR_2161

KPI:	D364_05810

KPX:	PMK1_03459(pgk_tpi)

KPNK:

BN49_2207

KVA:

Kvar_3260

KPE:	KPK_3433(tpiB)

KVQ:	SP68_24140

KOX:	KOX_17440(tpiA)

KOE:

A225_2341

KOY:	J415_20100(tpiA)

KOM:	HR38_15975

KOK:	KONIH1_11460

KQU:	AVR78_14660

EAR:

CCG30620

KQV:	B8P98_17630

KLL:	BJF97_11730

KLW:	DA718_17070

KAR:	LGL98_15620

REE:	electrica_03133(pgk_tpi)

ROR:	RORB6_09060(tpiA)

RAO:	DSD31_15660

RTG:	NCTC13098_01631(tpiA_2)

KIN:	AB182_28820

IZH:	FEM41_05115

GQU:	AWC35_18695

PCT:

PC1_0752

PWA:	Pecwa_0988

PPAR:

A8F97_13995

PEC:

W5S_0880

PBRA:

B5S52_17805

PPOO:

LW347_04110

CED:	LH89_02200

DFN:	CVE23_10570

DDA:	Dd703_2155

BGJ:	AWC36_04285

EBI:	EbC_33100(tpiA)

EPE:	CI789_01890

PAO:	Pat9b_4286

KLN:	LH22_13025

PANT:

PSNIH1_13315

PANS:

FCN45_09500

PDIS:

D8B20_08315

MTHI:

C7M52_01833(lerI)

PRAG:

EKN56_14710

LRI:	NCTC12151_02838(tpiA_2)

BSUN:

A4G13_10285

ASU:

Asuc_1601

VEU:	IXK98_05195

VBR:	A6E01_08970

VSH:	BSZ05_16665

VAS:	GT360_10370

PGB:	H744_2c2411

SPIU:

SPICUR_04425

SROS:

BBH56_05225

HHU:	AR456_16155

HSV:	HNO53_17790

HBH:	E4T21_17635

HAA:	A5892_00760

KUY:	FY550_15065

MMW:	Mmwyl1_3113

MME:	Marme_1597

MPRI:

MP3633_1150(eryH)

MARD:

IBG28_06500

MFOI:

JSY38_15335

MPRF:

J8N69_12390

TAU:

Tola_3162

ZDF:	AN401_08035

ORB:	IPMB12_04735

BHG:	I6G56_00465

BUD:	AQ610_18770

BUL:

BW21_6134

MLO:

mlr7275

MLN:	A9174_29240

MCI:	Mesci_5319

MCIC:

A4R28_00515

MOP:	Mesop_5784

MAM:	Mesau_05278

MAMO:

A6B35_10955

MESW:

A9K65_029075

MESM:

EJ066_15445

MHUA:

MCHK_0794

MJR:	EB229_29820

MERD:

EB233_25865

MESR:

FGU64_19820

MOH:	IHQ72_30710

MMEI:

LRP31_30040

SME:	SMc01614(tpiB)

SMK:	Sinme_2206

SMQ:	SinmeB_2050

SMX:	SM11_chr1033(tpiB)

SMI:	BN406_02050(tpiA2)

SMEG:

C770_GR4Chr2284

SMEL:

SM2011_c01614(tpiB)

SMER:

DU99_12485

SMD:

Smed_2150

RHI:	NGR_b17390(tpiA) NGR_c06610(tpiA)

SFH:	SFHH103_05477(tpiA)

SFD:	USDA257_c12890(tpiA1)

SIX:	BSY16_3605(tpiA)

SAME:

SAMCFNEI73_pC1161(tpiA)

SINO:

SS05631_b56460

ESJ:	SJ05684_c12460

ENU:	PYH37_004697

SKM:	PZL22_002562

EAD:	OV14_3639(tpiA)

EAH:	FA04_11220

ECAA:

J3R84_11375

ENP:	JVX98_08465

ARUI:

G6M88_17480

ASAL:

CFBP5507_25050

RET:	RHE_PF00040(tpiAf)

REC:	RHECIAT_PC0000966(tpiAc)

REL:	REMIM1_PF00044(tpiA-2)

REI:	IE4771_PA00088(tpiA-2)

RLE:	pRL120209(tpiA2)

RLT:	Rleg2_4651

RLG:

Rleg_5328

RLB:	RLEG3_09655

RTR:	RTCIAT899_PC05545(tpiA2)

RHL:	LPU83_pLPU83c0537(tpiA1)

RGA:	RGR602_PA00072(tpiA-2) RGR602_PC00573(tpiA-3)

RHN:	AMJ98_PE00043(tpiA-2)

RPHA:

AMC79_PD00973(tpiA-2)

RHX:	AMK02_PD00046(tpiA-2)

REZ:	AMJ99_PD00043(tpiA-2)

RJG:	CCGE525_32080

RHR:	CKA34_19845

RGR:	FZ934_27755

RAD:	CO657_24135 CO657_28375

RII:	FFM53_025705

RBAN:

J2J98_21265 J2J98_22035

RRG:	J3P73_25005

RLS:	HB780_03490

RAW:	NE851_33215

RSUL:

N2599_32165

RLW:	RlegWSM1455_24530

RRHO:

PR018_27280

RTU:	PR017_26055

ARA:	Arad_7454(tpiA)

RBW:	RLCC275e_24295

SHZ:

shn_16450

SZO:	K8M09_21695

SOJ:	K6301_17625 K6301_18150

SSUM:

Q9314_21740 Q9314_22265

BME:

BMEII0425

BMEL:

DK63_2814

BMI:	BMEA_B0848(tpiA)

BMZ:	BM28_B0836

BMG:	BM590_B0833(tpiA)

BMW:	BMNI_II0809

BMEE:

DK62_2584

BMF:	BAB2_0367(tpiA-2)

BMB:	BruAb2_0363(tpiA-2)

BMC:	BAbS19_II03450

BAA:	BAA13334_II00814

BABO:

DK55_2357

BABR:

DO74_2777

BABT:

DK49_2875

BABB:

DK48_2334

BABU:

DK53_2367

BABS:

DK51_2946

BABC:

DO78_2693

BMS:	BRA0869(tpiA-2)

BSI:	BS1330_II0862(tpiA)

BSF:	BSS2_II0823(tpiA)

BSUI:

BSSP1_II0814(tpiA)

BSUP:

BSPT1_II0811

BSUV:

BSPT2_II0812(tpiA)

BSUC:

BSSP2_II0823(tpiA)

BMT:	BSUIS_B0862(tpiA)

BSZ:

DK67_2823

BSV:	BSVBI22_B0861(tpiA)

BSW:	IY71_15340

BSG:	IY72_15290

BOV:	BOV_A0816(tpiA-1)

BCS:	BCAN_B0887(tpiA)

BSK:	BCA52141_II1815

BOL:	BCOUA_II0869(tpiA-2)

BCAR:

DK60_2560

BCAS:

DA85_14630

BMR:	BMI_II863(tpiA-2)

BPP:	BPI_II925(tpiA-2)

BPV:

DK65_2780

BCET:

V910_200423

BCEE:

V568_200475

BVL:	BF3285c2_0393(tpiA)

BRU:	BFS01_12150

BRJ:	BKD03_02225

OIN:	IAR37_20590

BIO:	BR141012304_20147

OAN:

Oant_2906

OAH:	DR92_3599(tpiA)

OPS:	A8A54_12250

BPSN:

NIK97_15380

OCH:	CES85_5814

OCR:	HGK82_17625

OCL:	GTN27_20235

LNE:	FZC33_03445

MMED:

Mame_00691(tpiA_1)

AUA:	M673_19620

AALA:

IGS74_12655

AALM:

LUX29_14545

LABT:

FIU93_29520(tpiA2)

LAGG:

B0E33_29595

LIZ:	LGH83_10295

RDE:	RD1_3625(tpiA)

RLI:	RLO149_c008400(tpiA1)

OAR:	OA238_c42210(tpiA2)

CMAR:

IMCC12053_1879

MALG:

MALG_04500

TPRO:

Ga0080559_TMP2168

MALU:

KU6B_05350(tpiA)

PALX:

GQA70_00770

PARR:

EOJ32_06630

PAAK:

FIU66_09000

PLIA:

E4191_09965

PMAU:

CP157_02316(eryH)

PSEW:

JHW44_18105

PSAP:

JHX88_17235

PFIS:

JHX87_06735

DON:	BSK21_15605

RBZ:	B9057_14885

THW:	BMG03_00150

TEC:	AKL02_018105

GFU:	KM031_19920

PAMO:

BAR1_01155

PPAF:

I8N54_11365

PBAE:

P8S53_18480

RBX:	I3V23_01185

GOX:

GOX2217

GOH:	B932_2981 B932_3439

GOY:	GLS_c05720(tpiA1) GLS_c23660(tpiA2)

GAL:	A0U94_09565 A0U94_09870

GTI:	FXF46_10940 FXF46_12655

GSP:	IGS75_03145

GFA:	MKW11_10745

KNA:	B0W47_16005

ABG:	Asbog_01354(tim)

KBA:	A0U89_08600

NCH:	A0U93_09645

LCK:	HN018_21600

RRF:	F11_07015(tpiA)

THAC:

CSC3H3_22335 CSC3H3_24060

PSYB:

KD050_04800

PUK:	PU629_02850

ELM:

ELI_4298

EMT:	CPZ25_014530

ELIM:

B2M23_01955

AWO:	Awo_c08970(tpiA1)

AWI:	CHL1_002879

LACY:

A4V08_22365

CSCI:

HDCHBGLK_01733(pgk_tpi)

CBOL:

CGC65_25820

LBW:	C3V36_01870

TEP:	TepRe1_2217

TAE:	TepiRe1_2385(tpiA)

MSM:	MSMEG_6785(tpiA)

MSG:	MSMEI_6603

MSB:	LJ00_33530

MSN:	LI99_33535

MSH:	LI98_33540

MPHL:

MPHLCCUG_03580(tpiA_2)

MLL:	B1R94_28265

MAUU:

NCTC10437_05453(tpiA_2)

MTY:	MTOK_43880(lerI)

MARZ:

MARA_39720(lerI)

MSEI:

MSEDJ_10890(lerI)

MGO:	AFA91_05895

SALU:

DC74_6851

SALL:

SAZ_35580

SRIM:

CP984_05210

MCAW:

F6J84_13140

CUM:	NI26_00160

CUB:	BJK06_07755

PLAP:

EAO79_04815

AGG:	C1N71_10430

ART:

Arth_0889

ARR:	ARUE_c10600(tpiA1) ARUE_c18620(tpiA2)

ARM:

ART_3800

ARW:	MB46_01315

ARH:	AHiyo8_30960

ARZ:	AUT26_04910

ARQ:	BWQ92_05635 BWQ92_12030

ARN:	CGK93_05760 CGK93_09910

ARX:	ARZXY2_2896(tpiA)

ARTH:

C3B78_10690

AAGI:

NCTC2676_1_00196(tpiA_1)

ASUN:

KG104_17300

AZX:	N2K95_15890

AAU:

AAur_1109

PUE:	FV140_05695

PNV:	JMY29_05220

APN:	Asphe3_20000

PSUL:

AU252_20985

PSEY:

GU243_03915 GU243_05095

KRS:	EQG70_16770

BCV:

Bcav_1549

BFA:	Bfae_00520

BRX:	BH708_13625

BRV:	CFK39_08505

BGG:	CFK41_17165

BSAU:

DWV08_14405

BRR:	C1N80_02510

BKI:	M4486_14675

BRHA:

NLU66_02720

BHH:	Bra3105_11710

HMM:	R3I40_09160

PSEI:

GCE65_11515

PFR:	PFREUD_22460(tpi2)

PFRE:

RM25_2126

PACD:

EGX94_08875

MPH:

MLP_03240

RAIN:

Rai3103_05835

NEC:	KGD82_11785

SNAH:

OUQ99_21640

SVI:	Svir_28670

AAB:	A4R43_00445

PSEA:

WY02_03010

PAUT:

Pdca_32700

ACTI:

UA75_20480

ACAD:

UA74_19980

ATIM:

CYJ17_0001090

PSUB:

Pelsub_P1002

KBS:	EPA93_22790

OBT:	OPIT5_28230

» show all

Reference

1 [PMID:25453104]

Authors

Barbier T, Collard F, Zuniga-Ripa A, Moriyon I, Godard T, Becker J, Wittmann C, Van Schaftingen E, Letesson JJ

Title

Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella.

Journal

Proc Natl Acad Sci U S A 111:17815-20 (2014)
DOI:10.1073/pnas.1414622111

Sequence

[bmf:BAB2_0367]

Other DBs

ExplorEnz - The Enzyme Database:

5.3.1.33

IUBMB Enzyme Nomenclature:

5.3.1.33

ExPASy - ENZYME nomenclature database:

5.3.1.33

BRENDA, the Enzyme Database:

5.3.1.33

DBGET integrated database retrieval system